Functional analysis of ATP binding cassette (ABC) transporters in Caenorhabditis Elegans (2005)
Thesis (Ph.D.) - Department of Molecular Biology and Biochemistry - Simon Fraser University
Sheps, Jonathan A, Ralph, Steven, Zhao, Zhongying, Baillie, David L, Ling, Victor
Abstract Background Many drugs of natural origin are hydrophobic and can pass through cell membranes. Hydrophobic molecules must be susceptible to active efflux systems if they are to be maintained...
Sheps, Jonathan A, Ralph, Steven, Zhao, Zhongying, Baillie, David L, Ling, Victor
The ABC transporters in the Caenorhabditis elegans genome have been identified and characterized. Phylogenetic analysis shows a large amount of gene loss and duplication, which is unusual for such a...
Identification of a nematode chemosensory gene family
Chen, Nansheng, Pai, Shraddha, Zhao, Zhongying, Mah, Allan, Newbury, Rebecca, Johnsen, Robert C., ...
Taking advantage of the recent availability of the whole genome sequence of Caenorhabditis briggsae, a closely related nematode to Caenorhabditis elegans, we have examined the chemosensory gene...
Sheps, Jonathan A, Ralph, Steven, Zhao, Zhongying, Baillie, David L, Ling, Victor
The ABC transporters in the Caenorhabditis elegans genome have been identified and characterized. Phylogenetic analysis shows a large amount of gene loss and duplication, which is unusual for such a...
Identification of a nematode chemosensory gene family
Chen, Nansheng, Pai, Shraddha, Zhao, Zhongying, Mah, Allan, Newbury, Rebecca, Johnsen, Robert C., ...
Taking advantage of the recent availability of the whole genome sequence of Caenorhabditis briggsae, a closely related nematode to Caenorhabditis elegans, we have examined the chemosensory gene...
Zhao, Zhongying, Thomas, James H., Chen, Nansheng, Sheps, Jonathan A., Baillie, David L.
ABC transporters constitute one of the largest gene families in all species. They are mostly involved in transport of substrates across membranes. We have previously demonstrated that the...