Zemin Zhang

Publication List Details

Period

1988 - 2008

Number

11

Co-Authors

Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective (2008)

Liu, Jinfeng, Zhang, Yan, Lei, Xingye, Zhang, Zemin

Abstract Background The rates of molecular evolution for protein-coding genes depend on the stringency of functional or structural constraints. The Ka/Ks ratio has been commonly used as an indicator...

The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression (2007)

Hon, Lawrence S, Zhang, Zemin

Abstract Background MicroRNAs (miRNAs) are small noncoding RNAs that bind mRNA target transcripts and repress gene expression. They have been implicated in multiple diseases, such as cancer, but the...

Sequences in the Aγ–δ intergenic region are not required for stage-specific regulation of the human β-globin gene locus

Gaensler, Karin M. L., Zhang, Zemin, Lin, Chin, Yang, Suya, Hardt, Karin, Flebbe-Rehwaldt, Linda

The human β-globin locus has been extensively studied as a model of tissue and developmental stage-specific gene expression. Structural mapping of naturally occurring mutations, including...

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Clark, Hilary F., Gurney, Austin L., Abaya, Evangeline, Baker, Kevin, Baldwin, Daryl, Brush, Jennifer, ...

A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological...

Sequences in the Aγ–δ intergenic region are not required for stage-specific regulation of the human β-globin gene locus

Gaensler, Karin M. L., Zhang, Zemin, Lin, Chin, Yang, Suya, Hardt, Karin, Flebbe-Rehwaldt, Linda

The human β-globin locus has been extensively studied as a model of tissue and developmental stage-specific gene expression. Structural mapping of naturally occurring mutations, including...

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Clark, Hilary F., Gurney, Austin L., Abaya, Evangeline, Baker, Kevin, Baldwin, Daryl, Brush, Jennifer, ...

A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological...

CanPredict: a computational tool for predicting cancer-associated missense mutations

Kaminker, Joshua S., Zhang, Yan, Watanabe, Colin, Zhang, Zemin

Various cancer genome projects are underway to identify novel mutations that drive tumorigenesis. While these screens will generate large data sets, the majority of identified missense changes are...

GeneHub-GEPIS: digital expression profiling for normal and cancer tissues based on an integrated gene database

Zhang, Yan, Luoh, Shiuh-Ming, Hon, Lawrence S., Baertsch, Robert, Wood, William I., Zhang, Zemin

GeneHub-GEPIS is a web application that performs digital expression analysis in human and mouse tissues based on an integrated gene database. Using aggregated expressed sequence tag (EST) library...

Signal peptide prediction based on analysis of experimentally verified cleavage sites

Zhang, Zemin, Henzel, William J.

A number of computational tools are available for detecting signal peptides, but their abilities to locate the signal peptide cleavage sites vary significantly and are often less than satisfactory....

The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression

Hon, Lawrence S, Zhang, Zemin

A genome wide analysis of factors affecting repression of mRNAs by microRNAs reveals roles for 3'UTR length, the number of target sites on the mRNA and the distance between pairs of binding sites.