Extensive phosphorylation of Smoothened in Hedgehog pathway activation
Zhang, Chi, Williams, Elizabeth H., Guo, Yurong, Lum, Lawrence, Beachy, Philip A.
The transmembrane protein Smoothened (Smo) is activated in response to the extracellular protein signal, Hedgehog (Hh), and transmits this state of pathway activity into the cell. Previous studies in...
Nuclear Import of TFIIB Is Mediated by Kap114p, a Karyopherin with Multiple Cargo-binding DomainsD⃞
Hodges, Jennifer L., Leslie, Jennifer H., Mosammaparast, Nima, Guo, Yurong, Shabanowitz, Jeffrey, Hunt, Donald F., ...
Nuclear import and export is mediated by an evolutionarily conserved family of soluble transport factors, the karyopherins (referred to as importins and exportins). The yeast karyopherin Kap114p has...
Extensive phosphorylation of Smoothened in Hedgehog pathway activation
Zhang, Chi, Williams, Elizabeth H., Guo, Yurong, Lum, Lawrence, Beachy, Philip A.
The transmembrane protein Smoothened (Smo) is activated in response to the extracellular protein signal, Hedgehog (Hh), and transmits this state of pathway activity into the cell. Previous studies in...
Nuclear Import of TFIIB Is Mediated by Kap114p, a Karyopherin with Multiple Cargo-binding DomainsD⃞
Hodges, Jennifer L., Leslie, Jennifer H., Mosammaparast, Nima, Guo, Yurong, Shabanowitz, Jeffrey, Hunt, Donald F., ...
Nuclear import and export is mediated by an evolutionarily conserved family of soluble transport factors, the karyopherins (referred to as importins and exportins). The yeast karyopherin Kap114p has...
Zhang, Jingyu, Harnpicharnchai, Piyanun, Jakovljevic, Jelena, Tang, Lan, Guo, Yurong, Oeffinger, Marlene, ...
More than 170 proteins are necessary for assembly of ribosomes in eukaryotes. However, cofactors that function with each of these proteins, substrates on which they act, and the precise functions of...
Nuclear Import of Histone H2a and H2b Is Mediated by a Network of Karyopherins
Mosammaparast, Nima, Jackson, Kelley R., Guo, Yurong, Brame, Cynthia J., Shabanowitz, Jeffrey, Hunt, Donald F., ...
The first step in the assembly of new chromatin is the cell cycle–regulated synthesis and nuclear import of core histones. The core histones include H2A and H2B, which are assembled into...