Yun-Liang Yang

Serum repressing efflux pump CDR1in Candida albicans (2006)

Yang, Yun-Liang, Lin, Yi-Hsuan, Tsao, Ming-Yang, Chen, Chia-Geun, Shih, Hsin-I, Fan, Jen-Chung, ...

Abstract Background In the past decades, the prevalence of candidemia has increased significantly and drug resistance has also become a pressing problem. Overexpression of CDR1 , an efflux pump, has...

Effect of prolonged HAART on oral colonization with Candidaand candidiasis (2006)

Yang, Yun-Liang, Lo, Hsiu-Jung, Hung, Chien-Ching, Li, Yichun

Abstract Background Progressive cell-mediated immunodeficiency with decrease of CD4+ lymphocyte count to less than or equal to 200 cells/mm 3 is a major risk factor for colonization with Candida...

The trend of susceptibilities to amphotericin B and fluconazole of Candidaspecies from 1999 to 2002 in Taiwan (2005)

Yang, Yun-Liang, Li, Shu-Ying, Cheng, Hsiao-Hsu, Lo, Hsiu-Jung, TSARY Hospitals

Abstract Background Candida species have various degrees of susceptibility to common antifungal drugs. The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing...

Risk factors for fatal candidemia caused by Candida albicansand non-albicans Candidaspecies (2005)

Cheng, Ming-Fang, Yang, Yun-Liang, Yao, Tzy-Jyun, Lin, Chin-Yu, Liu, Jih-Shin, Tang, Ran-Bin, ...

Abstract Background Invasive fungal infections, such as candidemia, caused by Candida species have been increasing. Candidemia is not only associated with a high mortality (30% to 40%) but also...

Comparing Lanes in the Pulsed-Field Gel Electrophoresis (PFGE) Images (2003)

Cheng, Wei-Zen, Yen, Kue-Sai, Lin, Chih-Yang, Ching, Yu-Tai, Yang, Yun-Liang

Pulsed-field Gel Electrophoresis (PFGE) is an important tool in genomic analysis. The result of PFGE is presented in an image. Each image contains several lanes. And each lane consists of bands. Two...

CaNdt80 Is Involved in Drug Resistance in Candida albicans by Regulating CDR1

Chen, Chia-Geun, Yang, Yun-Liang, Shih, Hsin-I, Su, Chia-Li, Lo, Hsiu-Jung

Overexpression of CDR1, an efflux pump, is one of the major mechanisms contributing to drug resistance in Candida albicans. CDR1 p-lacZ was constructed and transformed into a Saccharomyces cerevisiae...

Efg1 Involved in Drug Resistance by Regulating the Expression of ERG3 in Candida albicans

Lo, Hsiu-Jung, Wang, Jang-Shiun, Lin, Chih-Yang, Chen, Chia-Geun, Hsiao, Ting-Yin, Hsu, Chia-Tung, ...

The ERG3 gene in Candida albicans was identified as a gene whose mRNA level was higher in the cph1/cph1 efg1/efg1 double mutant than in the wild-type cells. Further study showed that Efg1, but not...

Colonization of Human Immunodeficiency Virus-Infected Outpatients in Taiwan with Candida Species

Hung, Chien-Ching, Yang, Yun-Liang, Lauderdale, Tsai-Ling, McDonald, L. Clifford, Hsiao, Chin-Fu, Cheng, Hsiao-Hsu, ...

To understand the Candida colonization of human immunodeficiency virus (HIV)-infected outpatients in Taiwan, we have conducted a prospective cohort study of Candida colonization and its risk factors...

CaNdt80 Is Involved in Drug Resistance in Candida albicans by Regulating CDR1

Chen, Chia-Geun, Yang, Yun-Liang, Shih, Hsin-I, Su, Chia-Li, Lo, Hsiu-Jung

Overexpression of CDR1, an efflux pump, is one of the major mechanisms contributing to drug resistance in Candida albicans. CDR1 p-lacZ was constructed and transformed into a Saccharomyces cerevisiae...

Efg1 Involved in Drug Resistance by Regulating the Expression of ERG3 in Candida albicans

Lo, Hsiu-Jung, Wang, Jang-Shiun, Lin, Chih-Yang, Chen, Chia-Geun, Hsiao, Ting-Yin, Hsu, Chia-Tung, ...

The ERG3 gene in Candida albicans was identified as a gene whose mRNA level was higher in the cph1/cph1 efg1/efg1 double mutant than in the wild-type cells. Further study showed that Efg1, but not...

Colonization of Human Immunodeficiency Virus-Infected Outpatients in Taiwan with Candida Species

Hung, Chien-Ching, Yang, Yun-Liang, Lauderdale, Tsai-Ling, McDonald, L. Clifford, Hsiao, Chin-Fu, Cheng, Hsiao-Hsu, ...

To understand the Candida colonization of human immunodeficiency virus (HIV)-infected outpatients in Taiwan, we have conducted a prospective cohort study of Candida colonization and its risk factors...

Combinatorial Computational Approaches to Identify Tetracycline Derivatives as Flavivirus Inhibitors

Yang, Jinn-Moon, Chen, Yan-Fu, Tu, Yu-Yin, Yen, Kuei-Rong, Yang, Yun-Liang

Limited structural information of drug targets, cellular toxicity possessed by lead compounds, and large amounts of potential leads are the major issues facing the design-oriented approach of...