Yulei Wang

Effect of various normalization methods on Applied Biosystems expression array system data (2006)

Barbacioru, Catalin C, Wang, Yulei, Canales, Roger D, Sun, Yongming A, Keys, David N, Chan, Frances, ...

Abstract Background DNA microarray technology provides a powerful tool for characterizing gene expression on a genome scale. While the technology has been widely used in discovery-based medical and...

Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms (2006)

Sørlie, Therese, Wang, Yulei, Xiao, Chunlin, Johnsen, Hilde, Naume, Bjørn, Samaha, Raymond R, ...

Abstract Background Gene expression profiling has been used to define molecular phenotypes of complex diseases such as breast cancer. The luminal A and basal-like subtypes have been repeatedly...

Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays (2006)

Wang, Yulei, Barbacioru, Catalin, Hyland, Fiona, Xiao, Wenming, Hunkapiller, Kathryn L, Blake, Julie, ...

Abstract Background DNA microarrays are rapidly becoming a fundamental tool in discovery-based genomic and biomedical research. However, the reliability of the microarray results is being challenged...

Precision and functional specificity in mRNA decay

Wang, Yulei, Liu, Chih Long, Storey, John D., Tibshirani, Robert J., Herschlag, Daniel, Brown, Patrick O.

Posttranscriptional processing of mRNA is an integral component of the gene expression program. By using DNA microarrays, we precisely measured the decay of each yeast mRNA, after thermal...

Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae

Arava, Yoav, Wang, Yulei, Storey, John D., Liu, Chih Long, Brown, Patrick O., Herschlag, Daniel

We have analyzed the translational status of each mRNA in rapidly growing Saccharomyces cerevisiae. mRNAs were separated by velocity sedimentation on a sucrose gradient, and 14 fractions across the...

Precision and functional specificity in mRNA decay

Wang, Yulei, Liu, Chih Long, Storey, John D., Tibshirani, Robert J., Herschlag, Daniel, Brown, Patrick O.

Posttranscriptional processing of mRNA is an integral component of the gene expression program. By using DNA microarrays, we precisely measured the decay of each yeast mRNA, after thermal...

Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae

Arava, Yoav, Wang, Yulei, Storey, John D., Liu, Chih Long, Brown, Patrick O., Herschlag, Daniel

We have analyzed the translational status of each mRNA in rapidly growing Saccharomyces cerevisiae. mRNAs were separated by velocity sedimentation on a sucrose gradient, and 14 fractions across the...