Yoonsoo Hahn

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

An international team has systematically validated and annotated just over 21,000 human genes using full-length cDNA, thereby providing a valuable new resource for the human genetics community.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate

Bera, Tapan K., Das, Sudipto, Maeda, Hiroshi, Beers, Richard, Wolfgang, Curt D., Kumar, Vasantha, ...

We identified a gene (NGEP) that is expressed only in prostate cancer and normal prostate. The two NGEP transcripts are 0.9 kb and 3.5 kb in size and are generated by a differential splicing event....

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

Hahn, Yoonsoo, Bera, Tapan Kumar, Gehlhaus, Kristen, Kirsch, Ilan R., Pastan, Ira H., Lee, Byungkook

Chromosomal rearrangements resulting in gene fusions are frequently involved in carcinogenesis. Here, we describe a semiautomatic procedure for identifying fusion gene transcripts by using publicly...

NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate

Bera, Tapan K., Das, Sudipto, Maeda, Hiroshi, Beers, Richard, Wolfgang, Curt D., Kumar, Vasantha, ...

We identified a gene (NGEP) that is expressed only in prostate cancer and normal prostate. The two NGEP transcripts are 0.9 kb and 3.5 kb in size and are generated by a differential splicing event....

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

Hahn, Yoonsoo, Bera, Tapan Kumar, Gehlhaus, Kristen, Kirsch, Ilan R., Pastan, Ira H., Lee, Byungkook

Chromosomal rearrangements resulting in gene fusions are frequently involved in carcinogenesis. Here, we describe a semiautomatic procedure for identifying fusion gene transcripts by using publicly...

Evolution and expression of chimeric POTE–actin genes in the human genome

Lee, Yoomi, Ise, Tomoko, Ha, Duc, Saint Fleur, Ashley, Hahn, Yoonsoo, Liu, Xiu-Fen, ...

We previously described a primate-specific gene family, POTE, that is expressed in many cancers but in a limited number of normal organs. The 13 POTE genes are dispersed among eight different...

Accurate quantitation of allele-specific expression patterns by analysis of DNA melting

Jeong, Sangkyun, Hahn, Yoonsoo, Rong, Qi, Pfeifer, Karl

Epigenetic and genetic mechanisms can result in large differences in expression levels of the two alleles in a diploid organism. Furthermore, these differences may be critical to phenotypic...

A model for obesity and gigantism due to disruption of the Ankrd26 gene

Bera, Tapan K., Liu, Xiu-Fen, Yamada, Masanori, Gavrilova, Oksana, Mezey, Eva, Tessarollo, Lino, ...

Obesity is a major health hazard that is caused by a combination of genetic and behavioral factors. Several models of obesity have been described in mice that have defects in the production of...