O'hUigin, Colm, Satta, Yoko, Takahata, Naoyuki, Klein, Jan
Molecular phylogenies of lineages that split from one another in short succession are often difficult to resolve because different loci and different sites within the same locus yield incongruent...
Takahata, Naoyuki, Satta, Yoko
To date major divergences that occurred in the primate lineage leading to modern humans and to infer a demographic parameter (effective population size) of the ancestral lineage that existed at each...
Kusaba, Makoto, Nishio, Takeshi, Satta, Yoko, Hinata, Kokichi, Ockendon, David
Self-incompatibility in Brassica is controlled by a single multi-allelic locus (S locus), which contains at least two highly polymorphic genes expressed in the stigma: an S glycoprotein gene (SLG)...
Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene
Hayakawa, Toshiyuki, Satta, Yoko, Gagneux, Pascal, Varki, Ajit, Takahata, Naoyuki
Inactivation of the CMP-N-acetylneuraminic acid hydroxylase gene has provided an example of human-specific genomic mutation that results in a widespread biochemical difference between human and...
Chou, Hsun-Hua, Hayakawa, Toshiyuki, Diaz, Sandra, Krings, Matthias, Indriati, Etty, Leakey, Meave, ...
Humans are genetically deficient in the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) because of an Alu-mediated inactivating mutation of the gene encoding the enzyme...
Shiba, Hiroshi, Iwano, Megumi, Entani, Tetsuyuki, Ishimoto, Kyoko, Shimosato, Hiroko, Che, Fang-Sik, ...
Self-incompatibility (SI) in Brassica is controlled sporophytically by the multiallelic S-locus. The SI phenotype of pollen in an S-heterozygote is determined by the relationship between the two...
The amelogenin loci span an ancient pseudoautosomal boundary in diverse mammalian species
Iwase, Mineyo, Satta, Yoko, Hirai, Yuriko, Hirai, Hirohisa, Imai, Hirotami, Takahata, Naoyuki
The mammalian amelogenin (AMEL) genes are found on both the X and Y chromosomes (gametologous). Comparison of the genomic AMEL sequences in five primates and three other mammals reveals that the 5′...
Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates
Go, Yasuhiro, Satta, Yoko, Takenaka, Osamu, Takahata, Naoyuki
Since the process of becoming dead genes or pseudogenes (pseudogenization) is irreversible and can occur rather rapidly under certain environmental circumstances, it is one plausible determinant for...
Hayakawa, Toshiyuki, Aki, Ikuko, Varki, Ajit, Satta, Yoko, Takahata, Naoyuki
The human CMP-N-acetylneuraminic acid hydroxylase gene (CMAH) suffered deletion of an exon that encodes an active center for the enzyme ∼3.2 million years ago (MYA). We analyzed a 7.3-kb intronic...
Kaneko, Satoko, Aki, Ikuko, Tsuda, Kaoru, Mekada, Kazuyuki, Moriwaki, Kazuo, Takahata, Naoyuki, ...
We investigate the origin and evolution of a mouse processed pseudogene, Makorin1-p1, whose transcripts stabilize functional Makorin1 mRNAs. It is shown that Makorin1-p1 originated almost immediately...
Coevolution of the S-locus genes SRK, SLG and SP11/SCR in Brassica oleracea and B. rapa.
Sato, Keiichi, Nishio, Takeshi, Kimura, Ryo, Kusaba, Makoto, Suzuki, Tohru, Hatakeyama, Katsunori, ...
Brassica self-incompatibility (SI) is controlled by SLG and SRK expressed in the stigma and by SP11/SCR expressed in the anther. We determined the sequences of the S domains of 36 SRK alleles, 13 SLG...
Sato, Akie, Satta, Yoko, Figueroa, Felipe, Mayer, Werner E, Zaleska-Rutczynska, Zofia, Toyosawa, Satoru, ...
The mangrove killifish Rivulus marmoratus, a neotropical fish in the order Cyprinodontiformes, is the only known obligatorily selfing, synchronous hermaphroditic vertebrate. To shed light on its...
Evolutionary relationships of major histocompatibility complex class I genes in simian primates.
Sawai, Hiromi, Kawamoto, Yoshi, Takahata, Naoyuki, Satta, Yoko
New World monkeys (NWMs) occupy a critical phylogenetic position in elucidating the evolutionary process of major histocompatibility complex (MHC) class I genes in primates. From three subfamilies of...
Takahata, Naoyuki, Satta, Yoko
To date major divergences that occurred in the primate lineage leading to modern humans and to infer a demographic parameter (effective population size) of the ancestral lineage that existed at each...
Kusaba, Makoto, Nishio, Takeshi, Satta, Yoko, Hinata, Kokichi, Ockendon, David
Self-incompatibility in Brassica is controlled by a single multi-allelic locus (S locus), which contains at least two highly polymorphic genes expressed in the stigma: an S glycoprotein gene (SLG)...
Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene
Hayakawa, Toshiyuki, Satta, Yoko, Gagneux, Pascal, Varki, Ajit, Takahata, Naoyuki
Inactivation of the CMP-N-acetylneuraminic acid hydroxylase gene has provided an example of human-specific genomic mutation that results in a widespread biochemical difference between human and...
Chou, Hsun-Hua, Hayakawa, Toshiyuki, Diaz, Sandra, Krings, Matthias, Indriati, Etty, Leakey, Meave, ...
Humans are genetically deficient in the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) because of an Alu-mediated inactivating mutation of the gene encoding the enzyme...
Shiba, Hiroshi, Iwano, Megumi, Entani, Tetsuyuki, Ishimoto, Kyoko, Shimosato, Hiroko, Che, Fang-Sik, ...
Self-incompatibility (SI) in Brassica is controlled sporophytically by the multiallelic S-locus. The SI phenotype of pollen in an S-heterozygote is determined by the relationship between the two...
The amelogenin loci span an ancient pseudoautosomal boundary in diverse mammalian species
Iwase, Mineyo, Satta, Yoko, Hirai, Yuriko, Hirai, Hirohisa, Imai, Hirotami, Takahata, Naoyuki
The mammalian amelogenin (AMEL) genes are found on both the X and Y chromosomes (gametologous). Comparison of the genomic AMEL sequences in five primates and three other mammals reveals that the 5′...
Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates
Go, Yasuhiro, Satta, Yoko, Takenaka, Osamu, Takahata, Naoyuki
Since the process of becoming dead genes or pseudogenes (pseudogenization) is irreversible and can occur rather rapidly under certain environmental circumstances, it is one plausible determinant for...
Hayakawa, Toshiyuki, Aki, Ikuko, Varki, Ajit, Satta, Yoko, Takahata, Naoyuki
The human CMP-N-acetylneuraminic acid hydroxylase gene (CMAH) suffered deletion of an exon that encodes an active center for the enzyme ∼3.2 million years ago (MYA). We analyzed a 7.3-kb intronic...
Kaneko, Satoko, Aki, Ikuko, Tsuda, Kaoru, Mekada, Kazuyuki, Moriwaki, Kazuo, Takahata, Naoyuki, ...
We investigate the origin and evolution of a mouse processed pseudogene, Makorin1-p1, whose transcripts stabilize functional Makorin1 mRNAs. It is shown that Makorin1-p1 originated almost immediately...
Coevolution of the S-locus genes SRK, SLG and SP11/SCR in Brassica oleracea and B. rapa.
Sato, Keiichi, Nishio, Takeshi, Kimura, Ryo, Kusaba, Makoto, Suzuki, Tohru, Hatakeyama, Katsunori, ...
Brassica self-incompatibility (SI) is controlled by SLG and SRK expressed in the stigma and by SP11/SCR expressed in the anther. We determined the sequences of the S domains of 36 SRK alleles, 13 SLG...
Sato, Akie, Satta, Yoko, Figueroa, Felipe, Mayer, Werner E, Zaleska-Rutczynska, Zofia, Toyosawa, Satoru, ...
The mangrove killifish Rivulus marmoratus, a neotropical fish in the order Cyprinodontiformes, is the only known obligatorily selfing, synchronous hermaphroditic vertebrate. To shed light on its...
Evolutionary relationships of major histocompatibility complex class I genes in simian primates.
Sawai, Hiromi, Kawamoto, Yoshi, Takahata, Naoyuki, Satta, Yoko
New World monkeys (NWMs) occupy a critical phylogenetic position in elucidating the evolutionary process of major histocompatibility complex (MHC) class I genes in primates. From three subfamilies of...
The origin and evolution of human ampliconic gene families and ampliconic structure
Bhowmick, Bejon Kumar, Satta, Yoko, Takahata, Naoyuki
Out of the nine male-specific gene families in the human Y chromosome amplicons, we investigate the origin and evolution of seven families for which gametologous and orthologous sequences are...
To understand the evolution of human mental activity, we performed population genetic analyses of nucleotide sequences (∼11 kb) from a worldwide sample of 60 chromosomes of the N-acylsphingosine...
Preservation of a Pseudogene by Gene Conversion and Diversifying Selection
Takuno, Shohei, Nishio, Takeshi, Satta, Yoko, Innan, Hideki
Interlocus gene conversion is considered a crucial mechanism for generating novel combinations of polymorphisms in duplicated genes. The importance of gene conversion between duplicated genes has...