Ferguson, Andrew D., Labunskyy , Vyacheslav, Fomenko, Dmitri E., Arac, Demet, Chelliah, Yogarany, Amexcua, Carlos A., ...
Selenium has significant health benefits, including potent cancer prevention activity and roles in immune function and the male reproductive system. Selenium-containing proteins, which incorporate...
Labunskyy, Vyacheslav M., Ferguson, Andrew D., Fomenko, Dmitri E., Chelliah, Yogarany, Hatfield, Dolph L., Gladyshev, Vadim N.
Selenium is an essential trace element with potent cancer prevention activity in mammals. The 15-kDa selenoprotein (Sep15) has been implicated in the chemopreventive effect of dietary selenium....
Chung-I Chang, Sébastien Pili-Floury, Mireille Hervé, Claudine Parquet, Yogarany Chelliah, Bruno Lemaitre, ...
The Drosophila protein PGRP-SA is found to have an intrinsic activity to cleave L,D-configured peptide bonds, which exist only in prokaryotes. This work reveals a rare enzymatic activity in a...
Chung-I Chang, Sébastien Pili-Floury, Mireille Hervé, Claudine Parquet, Yogarany Chelliah, Bruno Lemaitre, ...
The Drosophila peptidoglycan recognition protein SA (PGRP-SA) is critically involved in sensing bacterial infection and activating the Toll signaling pathway, which induces the expression of specific...
Chang, Chung-I, Pili-Floury, Sébastien, Hervé, Mireille, Parquet, Claudine, Chelliah, Yogarany, Lemaitre, Bruno, ...
The Drosophila peptidoglycan recognition protein SA (PGRP-SA) is critically involved in sensing bacterial infection and activating the Toll signaling pathway, which induces the expression of specific...
Chang, Chung-I, Ihara, Kentaro, Chelliah, Yogarany, Mengin-Lecreulx, Dominique, Wakatsuki, Soichi, Deisenhofer, Johann
The peptidoglycan-recognition protein LCa (PGRP-LCa) is a transmembrane receptor required for activation of the Drosophila immune deficiency pathway by monomeric Gram-negative peptidoglycan. We have...
Chang, Chung-I, Pili-Floury, Sébastien, Hervé, Mireille, Parquet, Claudine, Chelliah, Yogarany, Lemaitre, Bruno, ...
The Drosophila peptidoglycan recognition protein SA (PGRP-SA) is critically involved in sensing bacterial infection and activating the Toll signaling pathway, which induces the expression of specific...
Chang, Chung-I, Ihara, Kentaro, Chelliah, Yogarany, Mengin-Lecreulx, Dominique, Wakatsuki, Soichi, Deisenhofer, Johann
The peptidoglycan-recognition protein LCa (PGRP-LCa) is a transmembrane receptor required for activation of the Drosophila immune deficiency pathway by monomeric Gram-negative peptidoglycan. We have...
Signal transduction pathway of TonB-dependent transporters
Ferguson, Andrew D., Amezcua, Carlos A., Halabi, Najeeb M., Chelliah, Yogarany, Rosen, Michael K., Ranganathan, Rama, ...
Transcription of the ferric citrate import system is regulated by ferric citrate binding to the outer membrane transporter FecA. A signal indicating transporter occupancy is relayed across the outer...
Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Baxter, Richard H. G., Chang, Chung-I, Chelliah, Yogarany, Blandin, Stéphanie, Levashina, Elena A., Deisenhofer, Johann
Thioester-containing proteins (TEPs) are a major component of the innate immune response of insects to invasion by bacteria and protozoa. TEPs form a distinct clade of a superfamily that includes the...