Yang Xu

Publication List Details

Period

1988 - 2007

Number

73

Co-Authors

A rough sets based characteristic relation approach for dynamic attribute generalization in data mining (2007)

Li, Tianrui, WETS, Geert, Song, Jing, Xu, Yang, RUAN, Da

Any attribute set in an information system may be evolving in time when new information arrives. Approximations of a concept by rough set theory need updating for data mining or other related tasks....

A rough sets based characteristic relation approach for dynamic attribute generalization in data mining (2007)

Li, Tianrui, RUAN, Da, WETS, Geert, Song, Jing, Xu, Yang

Any attribute set in an information system may be evolving in time when new information arrives. Approximations of a concept by rough set theory need updating for data mining or other related tasks....

Differential expression of type X collagen in a mechanically active 3-D chondrocyte culture system: a quantitative study (2006)

Yang Xu, Vezeridis Peter, Nicholas Brian, Crisco Joseph, Moore Douglas, Chen Qian

Abstract Objective Mechanical loading of cartilage influences chondrocyte metabolism and gene expression. The gene encoding type X collagen is expressed specifically by hypertrophic chondrocytes and...

Synthesis and Characterization of Silica Coated CdSe/CdS Core/Shell Quantum Dots (2005)

Xu, Yang

A great deal of interest has been dawn on the colloidal chemistry based semiconductor nanocrysallites, also known as quantum dots (QDs). Because of the strong quantum confinement, quantum dots have...

Synthesis and Characterization of Silica Coated CdSe/CdS Core/Shell Quantum Dots (2005)

Xu, Yang

A great deal of interest has been dawn on the colloidal chemistry based semiconductor nanocrysallites, also known as quantum dots (QDs). Because of the strong quantum confinement, quantum dots have...

Synthesis and characterization of silica coated CdSe/CdS Core/Shell quantum dots [electronic resource] / (2005)

Xu, Yang.

A great deal of interest has been dawn on the colloidal chemistry based semiconductor nanocrysallites, also known as quantum dots (QDs). Because of the strong quantum confinement, quantum dots have...

Synthesis and characterization of silica coated CdSe/CdS Core/Shell quantum dots (2005)

Xu, Yang.

Thesis (Ph. D.)--Virginia Polytechnic Institute and State University, 2005.

ORACLE: Optimization with Recourse of Analog Circuits Including Layout Extraction (2004)

Yang Xu, Lawrence T. Pileggi, Stephen P. Boyd

Long design cycles due to the inability to predict silicon realities is a well-known problem that plagues analog/RF integrated circuit product development. As this problem worsens for technologies...

Coordinating Very Large Groups Of Wide Area Search Munitions (2004)

Paul Scerri, Elizabeth Liao, Justin Lai, Katia Sycara, Yang Xu, Mike Lewis

Coordinating hundreds or thousands of unmanned aerial vehicles (UAVs), presents a variety of new exciting challenges, over and above the challenges of building single UAVs and small teams of UAVs. We...

中国における会計任命制度の課題 : 企業統治の視点を求めて (2004)

徐, 陽, Xu, Yang, ジョ, ヨウ

はじめに 一 国有企業の改革 二 改革後の監督体制の問題点 三 会計任命制度の試行―コーポレートガバナンスの新形態 四 会計任命制度...

Identification and characterization of a novel nasopharyngeal carcinoma-associated peptide: NAP-1 (2004)

Li Feng, Yang Xu, Jiang Wei, Yin Zhi, Feng Xiang, Liu Wei, ...

Abstract Nasopharyngeal carcinoma (NPC) is one of the most commons cancers in Southeast Asia and Southern China. Several NPC-associated genes have been so far described and here we describe the...

SuperCube as a Model for Component Classification (2003)

Hamza H. Najapuka, Yang Xu

Classification is a general term that has drawn much attention in today`s market for software industry. It is a categorization that explains a group of entities with the particular behavior of those...

Structural and functional studies of (S)-mandelate dehydrogenase from Pseudomonas putida, a flavin-dependent alpha-hydroxyacid dehydrogenase (2001)

Xu, Yang

(S )-Mandelate dehydrogenase (MDH) from Pseudomonas putida , a member of the flavin mononucleotide-dependent α-hydroxyacid oxidase/dehydrogenase family, is a membrane-associated protein in...

Lattice Diagrams Using Reed-Muller Logic (1999)

Marek A. Perkowski, Malgorzata Chrzanowska-jeske, Yang Xu

Universal Akers Arrays (UAA) allow to realize arbitrary Boolean function directly in cellular layout but are very area-inefficient. This paper presents an extension of UAAs, called "Lattice Diagrams"...

A Regular Representation for Mapping to Fine-Grain, Locally-Connected FPGAs* (1999)

Malgorzata Chrzanowska-jeske, Zhi Wang, Yang Xu

A new data structure Pseudo-Symmetric Binary Decision Diagrams (PSBDDs) for completely specified Boolean functions has been proposed. The new diagrams are based on Ordered Binary Decision Diagrams...

Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl (1999)

Chen, Gang, Yuan, Shyng-Shiou F., Liu, Wei, Xu, Yang, Trujillo, Kelly, Song, Binwei, ...

Cells from individuals with the recessive cancer-prone disorder ataxia telangiectasia (A-T) are hypersensitive to ionizing radiation (I-R). ATM (mutated in A-T) is a protein kinase whose activity is...

Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atmminus /minus Mice (1998)

Xu, Yang, Yang, Eva Marie, Brugarolas, James, Jacks, Tyler, Baltimore, David

Disruption of the mouse Atm gene, whose human counterpart is consistently mutated in ataxia-telangiectasia (A-T) patients, creates an A-T mouse model exhibiting most of the A-T-related systematic and...

Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia-telangiectasia (1997)

Kuljis, Rodrigo O., Xu, Yang, Aguila, M. Cecilia, Baltimore, David

Neural degeneration is one of the clinical manifestations of ataxia-telangiectasia, a disorder caused by mutations in the Atm protein kinase gene, However, neural degeneration was not detected with...

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus (1996)

Xu, Yang, Davidson, Laurie, Alt, Frederick W., Baltimore, David

The pre-T-cell receptor, composed of the T-cell receptor (TCR) beta chain (TCR beta), pre-T alpha (pT alpha) chain, and CD3 molecules, has been postulated to be a transducer of signals during the...

The interaction between Hsp90 and Src /--by Yang Xu. (1996)

Xu, Yang.

Thesis (Ph. D.)--University of Chicago, Dept. of Biochemistry and Molecular Biology, December 1996.

An LL(1) binary tree grammar and its parser generator /--by Yang Xu. (1988)

Xu, Yang.

Advisor: Stanley C. Ahalt, Dept. of Electrical Engineering.

Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90

Xu, Yang, Singer, Mike A., Lindquist, Susan

Although Hsp90 displays general chaperone activity in vitro, few substrates of the chaperone have been identified in vivo, and the characteristics that render these substrates dependent on Hsp90...

Phosphorylation of murine p53 at Ser-18 regulates the p53 responses to DNA damage

Chao, Connie, Saito, Shin'ichi, Anderson, Carl W., Appella, Ettore, Xu, Yang

Ser-15 of human p53 (corresponding to Ser-18 of mouse p53) is phosphorylated by ataxia-telangiectasia mutated (ATM) family kinases in response to ionizing radiation (IR) and UV light. To determine...

Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia–telangiectasia

Kuljis, Rodrigo O., Xu, Yang, Aguila, M. Cecilia, Baltimore, David

Neural degeneration is one of the clinical manifestations of ataxia–telangiectasia, a disorder caused by mutations in the Atm protein kinase gene. However, neural degeneration was not detected with...

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

Sekiguchi, JoAnn, Ferguson, David O., Chen, Hua Tang, Yang, Eva Mary, Earle, John, Frank, Karen, ...

DNA ligase IV (Lig4) and the DNA-dependent protein kinase (DNA-PK) function in nonhomologous end joining (NHEJ). However, although Lig4 deficiency causes late embryonic lethality, deficiency in...

Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G1/S checkpoint activation in response to DNA damage

Post, Sean, Weng, Yi-Chinn, Cimprich, Karlene, Chen, Lan Bo, Xu, Yang

ATR [ataxia–telangiectasia-mutated (ATM)- and Rad3-related] is a protein kinase required for both DNA damage-induced cell cycle checkpoint responses and the DNA replication checkpoint that prevents...

Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm−/− Mice

Xu, Yang, Yang, Eva Marie, Brugarolas, James, Jacks, Tyler, Baltimore, David

Disruption of the mouse Atm gene, whose human counterpart is consistently mutated in ataxia-telangiectasia (A-T) patients, creates an A-T mouse model exhibiting most of the A-T-related systematic and...

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

Kang, Jian, Bronson, Roderick T., Xu, Yang

Nijmegen breakage syndrome (NBS) is an autosomal recessive hereditary disease that shares some common defects with ataxia–telangiectasia. The gene product mutated in NBS, named NBS1, is a component...

DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53

Woo, Richard A., Jack, Melissa T., Xu, Yang, Burma, Sandeep, Chen, David J., Lee, Patrick W.K.

Mouse embryo fibroblasts (MEFs) expressing the adenovirus E1A protein undergo apoptosis upon exposure to ionizing radiation. We show here that immediately following γ-irradiation, latent p53 formed...

Mutation of Mouse p53 Ser23 and the Response to DNA Damage

Wu, Zhiqun, Earle, John, Saito, Shin'ichi, Anderson, Carl W., Appella, Ettore, Xu, Yang

Recent studies have suggested that phosphorylation of human p53 at Ser20 is important for stabilizing p53 in response to DNA damage through disruption of the interaction between MDM2 and p53. To...

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

Chao, Connie, Saito, Shin’ichi, Kang, Jian, Anderson, Carl W., Appella, Ettore, Xu, Yang

p53-mediated transcription activity is essential for cell cycle arrest, but its importance for apoptosis remains controversial. To address this question, we employed homologous recombination and...

Functional Interaction of H2AX, NBS1, and p53 in ATM-Dependent DNA Damage Responses and Tumor Suppression

Kang, Jian, Ferguson, David, Song, Hoseok, Bassing, Craig, Eckersdorff, Mark, Alt, Frederick W., ...

Ataxia-telangiectasia (A-T) mutated (ATM) kinase signals all three cell cycle checkpoints after DNA double-stranded break (DSB) damage. H2AX, NBS1, and p53 are substrates of ATM kinase and are...

Immunization with the Gene Expressing Woodchuck Hepatitis Virus Nucleocapsid Protein Fused to Cytotoxic-T-Lymphocyte-Associated Antigen 4 Leads to Enhanced Specific Immune Responses in Mice and Woodchucks

Lu, Mengji, Isogawa, Masanori, Xu, Yang, Hilken, Gero

A number of options are available to modify and improve DNA vaccines. An interesting approach to improve DNA vaccines is to fuse bioactive domains, like cytotoxic-T-lymphocyte-associated protein 4...

Functional Analysis of the Roles of Posttranslational Modifications at the p53 C Terminus in Regulating p53 Stability and Activity

Feng, Lijin, Lin, Tongxiang, Uranishi, Hiroaki, Gu, Wei, Xu, Yang

Posttranslational modification of the tumor suppressor p53 plays important roles in regulating its stability and activity. Six lysine residues at the p53 C terminus can be posttranslationally...

Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90

Xu, Yang, Singer, Mike A., Lindquist, Susan

Although Hsp90 displays general chaperone activity in vitro, few substrates of the chaperone have been identified in vivo, and the characteristics that render these substrates dependent on Hsp90...

Phosphorylation of murine p53 at Ser-18 regulates the p53 responses to DNA damage

Chao, Connie, Saito, Shin'ichi, Anderson, Carl W., Appella, Ettore, Xu, Yang

Ser-15 of human p53 (corresponding to Ser-18 of mouse p53) is phosphorylated by ataxia-telangiectasia mutated (ATM) family kinases in response to ionizing radiation (IR) and UV light. To determine...

Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia–telangiectasia

Kuljis, Rodrigo O., Xu, Yang, Aguila, M. Cecilia, Baltimore, David

Neural degeneration is one of the clinical manifestations of ataxia–telangiectasia, a disorder caused by mutations in the Atm protein kinase gene. However, neural degeneration was not detected with...

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

Sekiguchi, JoAnn, Ferguson, David O., Chen, Hua Tang, Yang, Eva Mary, Earle, John, Frank, Karen, ...

DNA ligase IV (Lig4) and the DNA-dependent protein kinase (DNA-PK) function in nonhomologous end joining (NHEJ). However, although Lig4 deficiency causes late embryonic lethality, deficiency in...

Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G1/S checkpoint activation in response to DNA damage

Post, Sean, Weng, Yi-Chinn, Cimprich, Karlene, Chen, Lan Bo, Xu, Yang

ATR [ataxia–telangiectasia-mutated (ATM)- and Rad3-related] is a protein kinase required for both DNA damage-induced cell cycle checkpoint responses and the DNA replication checkpoint that prevents...

Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm−/− Mice

Xu, Yang, Yang, Eva Marie, Brugarolas, James, Jacks, Tyler, Baltimore, David

Disruption of the mouse Atm gene, whose human counterpart is consistently mutated in ataxia-telangiectasia (A-T) patients, creates an A-T mouse model exhibiting most of the A-T-related systematic and...

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

Kang, Jian, Bronson, Roderick T., Xu, Yang

Nijmegen breakage syndrome (NBS) is an autosomal recessive hereditary disease that shares some common defects with ataxia–telangiectasia. The gene product mutated in NBS, named NBS1, is a component...

DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53

Woo, Richard A., Jack, Melissa T., Xu, Yang, Burma, Sandeep, Chen, David J., Lee, Patrick W.K.

Mouse embryo fibroblasts (MEFs) expressing the adenovirus E1A protein undergo apoptosis upon exposure to ionizing radiation. We show here that immediately following γ-irradiation, latent p53 formed...

Mutation of Mouse p53 Ser23 and the Response to DNA Damage

Wu, Zhiqun, Earle, John, Saito, Shin'ichi, Anderson, Carl W., Appella, Ettore, Xu, Yang

Recent studies have suggested that phosphorylation of human p53 at Ser20 is important for stabilizing p53 in response to DNA damage through disruption of the interaction between MDM2 and p53. To...

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

Chao, Connie, Saito, Shin’ichi, Kang, Jian, Anderson, Carl W., Appella, Ettore, Xu, Yang

p53-mediated transcription activity is essential for cell cycle arrest, but its importance for apoptosis remains controversial. To address this question, we employed homologous recombination and...

Functional Interaction of H2AX, NBS1, and p53 in ATM-Dependent DNA Damage Responses and Tumor Suppression

Kang, Jian, Ferguson, David, Song, Hoseok, Bassing, Craig, Eckersdorff, Mark, Alt, Frederick W., ...

Ataxia-telangiectasia (A-T) mutated (ATM) kinase signals all three cell cycle checkpoints after DNA double-stranded break (DSB) damage. H2AX, NBS1, and p53 are substrates of ATM kinase and are...

Immunization with the Gene Expressing Woodchuck Hepatitis Virus Nucleocapsid Protein Fused to Cytotoxic-T-Lymphocyte-Associated Antigen 4 Leads to Enhanced Specific Immune Responses in Mice and Woodchucks

Lu, Mengji, Isogawa, Masanori, Xu, Yang, Hilken, Gero

A number of options are available to modify and improve DNA vaccines. An interesting approach to improve DNA vaccines is to fuse bioactive domains, like cytotoxic-T-lymphocyte-associated protein 4...

Functional Analysis of the Roles of Posttranslational Modifications at the p53 C Terminus in Regulating p53 Stability and Activity

Feng, Lijin, Lin, Tongxiang, Uranishi, Hiroaki, Gu, Wei, Xu, Yang

Posttranslational modification of the tumor suppressor p53 plays important roles in regulating its stability and activity. Six lysine residues at the p53 C terminus can be posttranslationally...

Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage†

Chao, Connie, Wu, Zhiqun, Mazur, Sharlyn J., Borges, Helena, Rossi, Matteo, Lin, Tongxiang, ...

Posttranslational modifications of p53, including phosphorylation and acetylation, play important roles in regulating p53 stability and activity. Mouse p53 is acetylated at lysine 317 by PCAF and at...

A Drosophila model of Barth syndrome

Xu, Yang, Condell, Morgan, Plesken, Heide, Edelman-Novemsky, Irit, Ma, Jinping, Ren, Mindong, ...

Barth syndrome is an X-linked disease presenting with cardiomyopathy and skeletal muscle weakness. It is caused by mutations in tafazzin, a putative acyl transferase that has been associated with...

Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression

Chao, Connie, Herr, Deron, Chun, Jerold, Xu, Yang

Mouse p53 is phosphorylated at Ser18 and Ser23 after DNA damage. To determine whether these two phosphorylation events have synergistic functions in activating p53 responses, we simultaneously...

Blockade of Platelet-Derived Growth Factor Receptor-β Pathway Induces Apoptosis of Vascular Endothelial Cells and Disrupts Glomerular Capillary Formation in Neonatal Mice

Sano, Hideto, Ueda, Yukihiko, Takakura, Nobuyuki, Takemura, Genzou, Doi, Toshio, Kataoka, Hiroshi, ...

Platelet-derived growth factor (PDGF), a potent chemotactic and proliferation factor for mesenchymal-derived cells, has been demonstrated to play critical roles in kidney development. Two receptors...

Antibody-catalyzed anaerobic destruction of methamphetamine

Xu, Yang, Hixon, Mark S., Yamamoto, Noboru, McAllister, Laura A., Wentworth, Anita D., Wentworth, Paul, ...

Methamphetamine [(+)-2] abuse has emerged as a fast-rising global epidemic, with immunopharmacotherapeutic approaches being sought for its treatment. Herein, we report the generation and...

The Amino Acid Residues at Positions 120 to 123 Are Crucial for the Antigenicity of Hepatitis B Surface Antigen▿

Tian, Yongjun, Xu, Yang, Zhang, Zhenhua, Meng, Zhongji, Qin, Li, Lu, Mengji, ...

The major hydrophilic region (MHR) of hepatitis B surface antigen (HBsAg) harbors conformational B-cell epitopes and is the major target of neutralizing antibodies to HBsAg (anti-HBs). Mutant HBsAg...

Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci

Inlay, Matthew A., Lin, Tongxiang, Gao, Heather H., Xu, Yang

V(D)J recombination of immunoglobulin (Ig) heavy (IgH) and light chain genes occurs sequentially in the pro– and pre–B cells. To identify cis-elements that dictate this order of rearrangement, we...

Important Roles for E Protein Binding Sites within the Immunoglobulin κ Chain Intronic Enhancer in Activating Vκ Jκ Rearrangement

Inlay, Matthew A., Tian, Hua, Lin, Tongxiang, Xu, Yang

The immunoglobulin κ light chain intronic enhancer (iEκ) activates κ rearrangement and is required to maintain the earlier or more efficient rearrangement of κ versus lambda (λ). To understand...

Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk

Ellmeier, Wilfried, Jung, Steffen, Sunshine, Mary Jean, Hatam, Farah, Xu, Yang, Baltimore, David, ...

The cytoplasmic protein tyrosine kinase Tec has been proposed to have important functions in hematopoiesis and lymphocyte signal transduction. Here we show that Tec-deficient mice developed normally...

Combination of an Antiviral Drug and Immunomodulation against Hepadnaviral Infection in the Woodchuck Model▿

Lu, Mengji, Yao, Xin, Xu, Yang, Lorenz, Heike, Dahmen, Uta, Chi, Haidong, ...

The essential role of multispecific immune responses for the control of hepatitis B virus (HBV) infection implies the need of multimodal therapeutic strategies for chronic HBV infection, including...

AN INTELLIGENT SENSORY EVALUATION METHOD FOR INDUSTRIAL PRODUCTS CHARACTERIZATION

YANG XU, XIANYI ZENG, LUDOVIC KOEHL

This paper presents a new method for sensory evaluation of industrial products with uncertain information. In this approach, sensory data provided by different evaluators are transformed into...