Yacine Graba

Distinct Hox protein sequences determine specificity in different tissues

Chauvet, Sophie, Merabet, Samir, Bilder, David, Scott, Matthew P., Pradel, Jacques, Graba, Yacine

Hox genes encode evolutionarily conserved transcription factors that control the morphological diversification along the anteroposterior (A/P) body axis. Expressed in precise locations in the...

Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis

Miotto, Benoit, Sagnier, Thierry, Berenger, Hélène, Bohmann, Dirk, Pradel, Jacques, Graba, Yacine

Gene regulation by AP-1 transcription factors in response to Jun N-terminal kinase (JNK) signaling controls essential cellular processes during development and in pathological situations. Here, we...

A green fluorescent protein reporter genetic screen that identifies modifiers of Hox gene function in the Drosophila embryo.

Merabet, Samir, Catala, Francoise, Pradel, Jacques, Graba, Yacine

Hox genes encode evolutionarily conserved transcription factors that play fundamental roles in the organization of the animal body plan. Molecular studies emphasize that unidentified genes contribute...

Distinct Hox protein sequences determine specificity in different tissues

Chauvet, Sophie, Merabet, Samir, Bilder, David, Scott, Matthew P., Pradel, Jacques, Graba, Yacine

Hox genes encode evolutionarily conserved transcription factors that control the morphological diversification along the anteroposterior (A/P) body axis. Expressed in precise locations in the...

Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis

Miotto, Benoit, Sagnier, Thierry, Berenger, Hélène, Bohmann, Dirk, Pradel, Jacques, Graba, Yacine

Gene regulation by AP-1 transcription factors in response to Jun N-terminal kinase (JNK) signaling controls essential cellular processes during development and in pathological situations. Here, we...

A green fluorescent protein reporter genetic screen that identifies modifiers of Hox gene function in the Drosophila embryo.

Merabet, Samir, Catala, Francoise, Pradel, Jacques, Graba, Yacine

Hox genes encode evolutionarily conserved transcription factors that play fundamental roles in the organization of the animal body plan. Molecular studies emphasize that unidentified genes contribute...

A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax

Merabet, Samir, Saadaoui, Mehdi, Sambrani, Nagraj, Hudry, Bruno, Pradel, Jacques, Affolter, Markus, ...

Hox transcription factors are essential for shaping body morphology in development and evolution. The control of Hox protein activity in part arises from interaction with the PBC class of partners,...