Xinyi Ngew

Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents▿ †

Teo, Jeanette W. P., Thayalan, Pamela, Beer, David, Yap, Amelia S. L., Nanjundappa, Mahesh, Ngew, Xinyi, ...

Peptide deformylase (PDF) catalyzes the hydrolytic removal of the N-terminal formyl group from nascent proteins. This is an essential step in bacterial protein synthesis, making PDF an attractive...