Xiao-Feng Qin

Induction of the HIV-1 Tat co-factor cyclin T1 during monocyte differentiation is required for the regulated expression of a large portion of cellular mRNAs (2006)

Yu, Wendong, Wang, Yan, Shaw, Chad A, Qin, Xiao-Feng, Rice, Andrew P

Abstract Background P-TEFb, a general RNA polymerase II elongation factor, is composed of CDK9 (cyclin-dependent kinase 9) as a catalytic unit and either cyclin T1, T2 or K as a regulatory subunit....

Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA (2004)

Hwang, Jong-Ik, Fraser, Iain D. C., Choi, Sangdun, Qin, Xiao-Feng, Simon, Melvin I.

Immune cells respond to chemotactic signals by means of G protein-coupled receptors. Attempts to elucidate the function of specific G protein family members in these responses is complicated by...

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5 (2003)

Qin, Xiao-Feng, An, Dong Sung, Chen, Irvin S. Y., Baltimore, David

Double-stranded RNAs approximate to 21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to reduce the expression of specific genes. To use them as reagents to...

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells (2002)

Yang, Lili, Qin, Xiao-Feng, Baltimore, David, Van Parijs, Luk

We have developed an alternative to transgenesis for producing antigen-specific T cells in vivo. In this system, clonal naive T cells with defined antigen specificity are generated by...

Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes (2002)

Dadgostar, Hajir, Zarnegar, Brian, Hoffmann, Alexander, Qin, Xiao-Feng, Truong, Uyen, Rao, Govinda, ...

CD40/CD40L interaction is essential for multiple biological events in T dependent humoral immune responses, including B cell survival and proliferation, germinal center and memory B cell formation,...

Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes

Dadgostar, Hajir, Zarnegar, Brian, Hoffmann, Alexander, Qin, Xiao-Feng, Truong, Uyen, Rao, Govinda, ...

CD40/CD40L interaction is essential for multiple biological events in T dependent humoral immune responses, including B cell survival and proliferation, germinal center and memory B cell formation,...

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells

Yang, Lili, Qin, Xiao-Feng, Baltimore, David, Van Parijs, Luk

We have developed an alternative to transgenesis for producing antigen-specific T cells in vivo. In this system, clonal naive T cells with defined antigen specificity are generated by...

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5

Qin, Xiao-Feng, An, Dong Sung, Chen, Irvin S. Y., Baltimore, David

Double-stranded RNAs ≈21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to reduce the expression of specific genes. To use them as reagents to protect cells...

Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA

Hwang, Jong-Ik, Fraser, Iain D. C., Choi, Sangdun, Qin, Xiao-Feng, Simon, Melvin I.

Immune cells respond to chemotactic signals by means of G protein-coupled receptors. Attempts to elucidate the function of specific G protein family members in these responses is complicated by...

Potent In Vitro Synergism of Fluconazole and Berberine Chloride against Clinical Isolates of Candida albicans Resistant to Fluconazole

Quan, Hua, Cao, Ying-Ying, Xu, Zheng, Zhao, Jing-Xia, Gao, Ping-Hui, Qin, Xiao-Feng, ...

In vitro interaction of fluconazole and berberine chloride was investigated against 40 fluconazole-resistant clinical isolates of Candida albicans. Synergism in fungistatic activity was found with...

Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes

Dadgostar, Hajir, Zarnegar, Brian, Hoffmann, Alexander, Qin, Xiao-Feng, Truong, Uyen, Rao, Govinda, ...

CD40/CD40L interaction is essential for multiple biological events in T dependent humoral immune responses, including B cell survival and proliferation, germinal center and memory B cell formation,...

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells

Yang, Lili, Qin, Xiao-Feng, Baltimore, David, Van Parijs, Luk

We have developed an alternative to transgenesis for producing antigen-specific T cells in vivo. In this system, clonal naive T cells with defined antigen specificity are generated by...

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5

Qin, Xiao-Feng, An, Dong Sung, Chen, Irvin S. Y., Baltimore, David

Double-stranded RNAs ≈21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to reduce the expression of specific genes. To use them as reagents to protect cells...

Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA

Hwang, Jong-Ik, Fraser, Iain D. C., Choi, Sangdun, Qin, Xiao-Feng, Simon, Melvin I.

Immune cells respond to chemotactic signals by means of G protein-coupled receptors. Attempts to elucidate the function of specific G protein family members in these responses is complicated by...

Potent In Vitro Synergism of Fluconazole and Berberine Chloride against Clinical Isolates of Candida albicans Resistant to Fluconazole

Quan, Hua, Cao, Ying-Ying, Xu, Zheng, Zhao, Jing-Xia, Gao, Ping-Hui, Qin, Xiao-Feng, ...

In vitro interaction of fluconazole and berberine chloride was investigated against 40 fluconazole-resistant clinical isolates of Candida albicans. Synergism in fungistatic activity was found with...

Plasmacytoid dendritic cells prime IL-10–producing T regulatory cells by inducible costimulator ligand

Ito, Tomoki, Yang, Maria, Wang, Yui-Hsi, Lande, Roberto, Gregorio, Josh, Perng, Olivia A, ...

Although there is evidence for distinct roles of myeloid dendritic cells (DCs [mDCs]) and plasmacytoid pre-DCs (pDCs) in regulating T cell–mediated adaptive immunity, the concept of functional DC...

MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte–macrophage colony-stimulating factor production in macrophages

Kim, Kihwan, Duramad, Omar, Qin, Xiao-Feng, Su, Bing

Mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a Ser/Thr protein kinase belonging to the MEKK/STE11 subgroup of the MAP3K family. Recently, we found that MEKK3 plays a critical role in...