Wouter H. Lamers

The transcriptomic signature of fasting murine liver (2008)

Sokolović, Milka, Sokolović, Aleksandar, Wehkamp, Diederik, Van Themaat, Emiel, De Waart, Dirk R, Gilhuijs-Pederson, Lisa A, ...

Abstract Background The contribution of individual organs to the whole-body adaptive response to fasting has not been established. Hence, gene-expression profiling, pathway, network and gene-set...

Fasting induces a biphasic adaptive metabolic response in murine small intestine (2007)

Sokolović, Milka, Wehkamp, Diederik, Sokolović, Aleksandar, Vermeulen, Jacqueline, Gilhuijs-Pederson, Lisa A, Van Haaften, Rachel IM, ...

Abstract Background The gut is a major energy consumer, but a comprehensive overview of the adaptive response to fasting is lacking. Gene-expression profiling, pathway analysis, and...

Comparative proteomic analysis of cell lines and scrapings of the human intestinal epithelium (2007)

Lenaerts, Kaatje, Bouwman, Freek G, Lamers, Wouter H, Renes, Johan, Mariman, Edwin C

Abstract Background In vitro models are indispensable study objects in the fields of cell and molecular biology, with advantages such as accessibility, homogeneity of the cell population,...

Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology (2006)

Ruijter, Jan M, Thygesen, Helene H, Schoneveld, Onard JLM, Das, Atze T, Berkhout, Ben, Lamers, Wouter H

Abstract Background In experimental biology, including retrovirology and molecular biology, replicate measurement sessions very often show similar proportional differences between experimental...

Glucocorticoid receptor, C/EBP, HNF3, and protein kinase A coordinately activate the glucocorticoid response unit of the carbamoylphosphate synthetase I gene. (1998)

Christoffels, Vincent M., Grange, Thierry, Kaestner, Klaus H., Cole, Timothy J., Darlington, Gretchen J., Croniger, Colleen M., ...

A single far-upstream enhancer is sufficient to confer hepatocyte-specific, glucocorticoid- and cyclic AMP-inducible periportal expression to the carbamoylphosphate synthetase I (CPS) gene. To...

Glucocorticoid Receptor, C/EBP, HNF3, and Protein Kinase A Coordinately Activate the Glucocorticoid Response Unit of the Carbamoylphosphate Synthetase I Gene

Christoffels, Vincent M., Grange, Thierry, Kaestner, Klaus H., Cole, Timothy J., Darlington, Gretchen J., Croniger, Colleen M., ...

A single far-upstream enhancer is sufficient to confer hepatocyte-specific, glucocorticoid- and cyclic AMP-inducible periportal expression to the carbamoylphosphate synthetase I (CPS) gene. To...

Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice

De Jonge, Wouter J., Kwikkers, Karin L., Te Velde, Anje A., Nolte, Martijn A., Mebius, Reina E., ...

Apart from its role in the synthesis of protein and nitric oxide (NO), and in ammonia detoxification, the amino acid arginine exerts an immunosupportive function. We have studied the role of arginine...

Septation and separation within the outflow tract of the developing heart

Webb, Sandra, Qayyum, Sonia R, Anderson, Robert H, Lamers, Wouter H, Richardson, Michael K

The developmental anatomy of the ventricular outlets and intrapericardial arterial trunks is a source of considerable confusion. First, major problems exist because of the multiple names and...

Glucocorticoid Receptor, C/EBP, HNF3, and Protein Kinase A Coordinately Activate the Glucocorticoid Response Unit of the Carbamoylphosphate Synthetase I Gene

Christoffels, Vincent M., Grange, Thierry, Kaestner, Klaus H., Cole, Timothy J., Darlington, Gretchen J., Croniger, Colleen M., ...

A single far-upstream enhancer is sufficient to confer hepatocyte-specific, glucocorticoid- and cyclic AMP-inducible periportal expression to the carbamoylphosphate synthetase I (CPS) gene. To...

Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice

De Jonge, Wouter J., Kwikkers, Karin L., Te Velde, Anje A., Nolte, Martijn A., Mebius, Reina E., ...

Apart from its role in the synthesis of protein and nitric oxide (NO), and in ammonia detoxification, the amino acid arginine exerts an immunosupportive function. We have studied the role of arginine...

Septation and separation within the outflow tract of the developing heart

Webb, Sandra, Qayyum, Sonia R, Anderson, Robert H, Lamers, Wouter H, Richardson, Michael K

The developmental anatomy of the ventricular outlets and intrapericardial arterial trunks is a source of considerable confusion. First, major problems exist because of the multiple names and...

In vivo measurement of nitric oxide production in porcine gut, liver and muscle during hyperdynamic endotoxaemia

Bruins, Maaike J, Lamers, Wouter H, Meijer, Alfred J, Soeters, Peter B, Deutz, Nicolaas E P

During prolonged endotoxaemia, an increase in arginine catabolism may result in limiting substrate availability for nitric oxide (NO) production. These effects were quantitated in a chronically...