Woubalem Birmachu

Comparison of human B cell activation by TLR7 and TLR9 agonists (2008)

Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Alkan, Sefik S, ...

Abstract Background Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in...

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists (2007)

Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, ...

Abstract Background Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blood mononuclear cells and are the primary type 1 interferon (IFN), producing cells, secreting high...

Immune-mediated changes in actinic keratosis following topical treatment with imiquimod 5% cream (2007)

Torres, Abel, Storey, Leslie, Anders, Makala, Miller, Richard L, Bulbulian, Barbara J, Jin, Jizhong, ...

Abstract Background The objective of this study was to identify the molecular processes responsible for the anti-lesional activity of imiquimod in subjects with actinic keratosis using global gene...