Sipe, Walter E. B., Brierley, Stuart Matthew, Martin, Christopher Mark, Phillis, Benjamin David, Cruz, Francisco Bautista, Grady, Eileen F., ...
Copyright © 2008 by the American Physiological Society
Sipe, Walter E. B., Brierley, Stuart Matthew, Martin, Christopher Mark, Phillis, Benjamin David, Cruz, Francisco Bautista, Grady, Eileen F., ...
Copyright © 2008 by the American Physiological Society
Abnormal osmotic regulation in trpv4-/- mice
Liedtke, Wolfgang, Friedman, Jeffrey M.
Osmotic homeostasis is one of the most aggressively defended physiological parameters in vertebrates. However, the molecular mechanisms underlying osmotic regulation are poorly understood. The...
Liedtke, Wolfgang, Tobin, David M., Bargmann, Cornelia I., Friedman, Jeffrey M.
All animals detect osmotic and mechanical stimuli, but the molecular basis for these responses is incompletely understood. The vertebrate transient receptor potential channel vanilloid subfamily 4...
The TRPV4 ion channel, previously named vanilloid receptor-related osmotically activated channel (VR-OAC), functions in vivo in the transduction of osmotic and mechanical stimuli. In trpv4 null mice,...
Abnormal osmotic regulation in trpv4-/- mice
Liedtke, Wolfgang, Friedman, Jeffrey M.
Osmotic homeostasis is one of the most aggressively defended physiological parameters in vertebrates. However, the molecular mechanisms underlying osmotic regulation are poorly understood. The...
Liedtke, Wolfgang, Tobin, David M., Bargmann, Cornelia I., Friedman, Jeffrey M.
All animals detect osmotic and mechanical stimuli, but the molecular basis for these responses is incompletely understood. The vertebrate transient receptor potential channel vanilloid subfamily 4...
The TRPV4 ion channel, previously named vanilloid receptor-related osmotically activated channel (VR-OAC), functions in vivo in the transduction of osmotic and mechanical stimuli. In trpv4 null mice,...
Liedtke, Wolfgang, Leman, Elizabeth E., Fyffe, Robert E. W., Raine, Cedric S., Schubart, Ulrich K.
Stathmin is a cytosolic protein that binds tubulin and destabilizes cellular microtubules, an activity regulated by phosphorylation. Despite its abundant expression in the developing mammalian...
Arterial Response to Shear Stress Critically Depends on Endothelial TRPV4 Expression
Hartmannsgruber, Veronika, Heyken, Willm-Thomas, Kacik, Michael, Kaistha, Anuradha, Grgic, Ivica, Harteneck, Christian, ...
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding
Gevaert, Thomas, Vriens, Joris, Segal, Andrei, Everaerts, Wouter, Roskams, Tania, Talavera, Karel, ...
Here we provide evidence for a critical role of the transient receptor potential cation channel, subfamily V, member 4 (TRPV4) in normal bladder function. Immunofluorescence demonstrated TRPV4...
Grant, Andrew D, Cottrell, Graeme S, Amadesi, Silvia, Trevisani, Marcello, Nicoletti, Paola, Materazzi, Serena, ...
Exacerbated sensitivity to mechanical stimuli that are normally innocuous or mildly painful (mechanical allodynia and hyperalgesia) occurs during inflammation and underlies painful diseases....
How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways
Simon, Sidney A., Liedtke, Wolfgang
Airway irritants cause a variety of lung pathologies. Two separate studies, the first recently reported in the JCI by Bessac et al. and the second reported by Andrè et al. in the current issue of...