Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation
Béraud, Christophe, Henzel, William J., Baeuerle, Patrick A.
Hypoxia, reoxygenation, and the tyrosine phosphatase inhibitor pervanadate activate the transcription factor NF-κB, involving phosphorylation of its inhibitor IκB-α on tyrosine 42. This...
Derepression of the C/EBPα gene during adipogenesis: Identification of AP-2α as a repressor
Jiang, Man-Shiow, Tang, Qi-Qun, McLenithan, John, Geiman, Deb, Shillinglaw, Wendy, Henzel, William J., ...
During adipogenesis, CCAAT/enhancer binding protein α (C/EBPα) serves as a pleiotropic transcriptional activator of adipocyte genes. Previously, we identified dual repressive elements in the...
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
Yamashita, Hiromi, Takenoshita, Makoto, Sakurai, Masaharu, Bruick, Richard K., Henzel, William J., Shillinglaw, Wendy, ...
Carbohydrates mediate their conversion to triglycerides in the liver by promoting both rapid posttranslational activation of rate-limiting glycolytic and lipogenic enzymes and transcriptional...
Bonnard, Madeleine, Mirtsos, Christine, Suzuki, Shinobu, Graham, Kevin, Huang, Jianing, Ng, Michelle, ...
Induction of NF-κB-dependent transcription requires phosphorylation and subsequent degradation of I-κB, an inhibitor of NF-κB, followed by nuclear translocation and DNA binding of NF-κB. Tumor...
Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation
Béraud, Christophe, Henzel, William J., Baeuerle, Patrick A.
Hypoxia, reoxygenation, and the tyrosine phosphatase inhibitor pervanadate activate the transcription factor NF-κB, involving phosphorylation of its inhibitor IκB-α on tyrosine 42. This...
Derepression of the C/EBPα gene during adipogenesis: Identification of AP-2α as a repressor
Jiang, Man-Shiow, Tang, Qi-Qun, McLenithan, John, Geiman, Deb, Shillinglaw, Wendy, Henzel, William J., ...
During adipogenesis, CCAAT/enhancer binding protein α (C/EBPα) serves as a pleiotropic transcriptional activator of adipocyte genes. Previously, we identified dual repressive elements in the...
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
Yamashita, Hiromi, Takenoshita, Makoto, Sakurai, Masaharu, Bruick, Richard K., Henzel, William J., Shillinglaw, Wendy, ...
Carbohydrates mediate their conversion to triglycerides in the liver by promoting both rapid posttranslational activation of rate-limiting glycolytic and lipogenic enzymes and transcriptional...
Bonnard, Madeleine, Mirtsos, Christine, Suzuki, Shinobu, Graham, Kevin, Huang, Jianing, Ng, Michelle, ...
Induction of NF-κB-dependent transcription requires phosphorylation and subsequent degradation of I-κB, an inhibitor of NF-κB, followed by nuclear translocation and DNA binding of NF-κB. Tumor...
Signal peptide prediction based on analysis of experimentally verified cleavage sites
Zhang, Zemin, Henzel, William J.
A number of computational tools are available for detecting signal peptides, but their abilities to locate the signal peptide cleavage sites vary significantly and are often less than satisfactory....
Wilhelm, James E., Hilton, Meredith, Amos, Quinlan, Henzel, William J.
In Drosophila oocytes, precise localization of the posterior determinant, Oskar, is required for posterior patterning. This precision is accomplished by a localization-dependent translational control...