Distinct Regions of the Interleukin-7 Receptor Regulate Different Bcl2 Family Members
Jiang, Qiong, Li, Wen Qing, Hofmeister, Robert R., Young, Howard A., Hodge, David R., Keller, Jonathan R., ...
The antiapoptotic function of the interleukin-7 (IL-7) receptor is related to regulation of three members of the Bcl2 family: synthesis of Bcl2, phosphorylation of Bad, and cytosolic retention of...
Liacini, Abdelhamid, Sylvester, Judith, Li, Wen Qing, Zafarullah, Muhammad
Interleukin-1 (IL-1), IL-17 and tumor necrosis factor alpha (TNF-α) are the main proinflammatory cytokines implicated in cartilage breakdown by matrix metalloproteinase (MMPs) in arthritic joints....
Distinct Regions of the Interleukin-7 Receptor Regulate Different Bcl2 Family Members
Jiang, Qiong, Li, Wen Qing, Hofmeister, Robert R., Young, Howard A., Hodge, David R., Keller, Jonathan R., ...
The antiapoptotic function of the interleukin-7 (IL-7) receptor is related to regulation of three members of the Bcl2 family: synthesis of Bcl2, phosphorylation of Bad, and cytosolic retention of...
Liacini, Abdelhamid, Sylvester, Judith, Li, Wen Qing, Zafarullah, Muhammad
Interleukin-1 (IL-1), IL-17 and tumor necrosis factor alpha (TNF-α) are the main proinflammatory cytokines implicated in cartilage breakdown by matrix metalloproteinase (MMPs) in arthritic joints....
IL-7 promotes T cell proliferation through destabilization of p27Kip1
Li, Wen Qing, Jiang, Qiong, Aleem, Eiman, Kaldis, Philipp, Khaled, Annette R., Durum, Scott K.
Interleukin (IL)-7 is required for survival and homeostatic proliferation of T lymphocytes. The survival effect of IL-7 is primarily through regulation of Bcl-2 family members; however, the...
Cytokine-driven cell cycling is mediated through Cdc25A
Khaled, Annette R., Bulavin, Dmitry V., Kittipatarin, Christina, Li, Wen Qing, Alvarez, Michelle, Kim, Kyungjae, ...
Lymphocytes are the central mediators of the immune response, requiring cytokines for survival and proliferation. Survival signaling targets the Bcl-2 family of apoptotic mediators, however, the...