Grosjean, Henri, Gaspin, Christine, Marck, Christian, Decatur, Wayne A
Abstract Background Naturally occurring RNAs contain numerous enzymatically altered nucleosides. Differences in RNA populations (RNomics) and pattern of RNA modifications (Modomics) depends on the...
King, Thomas H., Decatur, Wayne A., Bertrand, Edouard, Maxwell, E. Stuart, Fournier, Maurille J.
Biogenesis of small nucleolar RNA-protein complexes (snoRNPs) consists of synthesis of the snoRNA and protein components, snoRNP assembly, and localization to the nucleolus. Recently, two...
Schattner, Peter, Decatur, Wayne A., Davis, Carrie A., Ares, Manuel, Fournier, Maurille J., Lowe, Todd M.
One of the largest families of small RNAs in eukaryotes is the H/ACA small nucleolar RNAs (snoRNAs), most of which guide RNA pseudouridine formation. So far, an effective computational method...
King, Thomas H., Decatur, Wayne A., Bertrand, Edouard, Maxwell, E. Stuart, Fournier, Maurille J.
Biogenesis of small nucleolar RNA-protein complexes (snoRNPs) consists of synthesis of the snoRNA and protein components, snoRNP assembly, and localization to the nucleolus. Recently, two...
Schattner, Peter, Decatur, Wayne A., Davis, Carrie A., Ares, Manuel, Fournier, Maurille J., Lowe, Todd M.
One of the largest families of small RNAs in eukaryotes is the H/ACA small nucleolar RNAs (snoRNAs), most of which guide RNA pseudouridine formation. So far, an effective computational method...
A systematic, ligation-based approach to study RNA modifications
Saikia, Mridusmita, Dai, Qing, Decatur, Wayne A., Fournier, Maurille J., Piccirilli, Joseph A., Pan, Tao
Over 100 different chemical types of modifications have been identified in thousands of sites in tRNAs, rRNAs, mRNAs, small nuclear RNAs, and other RNAs. Some modifications are highly conserved,...
New bioinformatic tools for analysis of nucleotide modifications in eukaryotic rRNA
Piekna-Przybylska, Dorota, Decatur, Wayne A., Fournier, Maurille J.
This report presents a valuable new bioinformatics package for research on rRNA nucleotide modifications in the ribosome, especially those created by small nucleolar RNA:protein complexes (snoRNPs)....
Hatin, Isabelle, Fabret, Céline, Namy, Olivier, Decatur, Wayne A., Rousset, Jean-Pierre
In eukaryotes, release factors 1 and 3 (eRF1 and eRF3) are recruited to promote translation termination when a stop codon on the mRNA enters at the ribosomal A-site. However, their overexpression...
The 3D rRNA modification maps database: with interactive tools for ribosome analysis
Piekna-Przybylska, Dorota, Decatur, Wayne A., Fournier, Maurille J.
The 3D rRNA modification maps database is the first general resource of information about the locations of modified nucleotides within the 3D structure of the full ribosome, with mRNA and tRNAs in...
Different Mechanisms for Pseudouridine Formation in Yeast 5S and 5.8S rRNAs▿
Decatur, Wayne A., Schnare, Murray N.
The selection of sites for pseudouridylation in eukaryotic cytoplasmic rRNA occurs by the base pairing of the rRNA with specific guide sequences within the RNA components of box H/ACA small nucleolar...