Vu H. Nguyen

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

Zeiser, Robert, Nguyen, Vu H., Beilhack, Andreas, Buess, Martin, Schulz, Stephan, Baker, Jeanette, ...

CD4+CD25+ regulatory T (Treg) cells control immunologic tolerance and antitumor immune responses. Therefore, in vivo modification of Treg function by immunosuppressant drugs has broad implications...

Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease

Zeiser, Robert, Nguyen, Vu H., Hou, Jing-Zhou, Beilhack, Andreas, Zambricki, Elizabeth, Buess, Martin, ...

Murine CD4+CD25+ regulatory T cells (Treg cells) reduce acute graft-versus-host disease (aGvHD). However, surface molecules critical for suppression are unclear. Deficiency of CD30 (CD30−/−)...