Volker F. Wendisch

Nitrogen regulatory protein C-controlled genes of Escherichia coli: Scavenging as a defense against nitrogen limitation

Zimmer, Daniel P., Soupene, Eric, Lee, Haidy L., Wendisch, Volker F., Khodursky, Arkady B., Peter, Brian J., ...

Nitrogen regulatory protein C (NtrC) of enteric bacteria activates transcription of genes/operons whose products minimize the slowing of growth under nitrogen-limiting conditions. To reveal the NtrC...

Quantitative Determination of Metabolic Fluxes during Coutilization of Two Carbon Sources: Comparative Analyses with Corynebacterium glutamicum during Growth on Acetate and/or Glucose†

Wendisch, Volker F., De Graaf, Albert A., Sahm, Hermann, Eikmanns, Bernhard J.

Growth of Corynebacterium glutamicum on mixtures of the carbon sources glucose and acetate is shown to be distinct from growth on either substrate alone. The organism showed nondiauxic growth on...

The Phosphate Starvation Stimulon of Corynebacterium glutamicum Determined by DNA Microarray Analyses

Ishige, Takeru, Krause, Malgorzata, Bott, Michael, Wendisch, Volker F., Sahm, Hermann

The phosphate (Pi) starvation stimulon of Corynebacterium glutamicum was characterized by global gene expression analysis by using DNA microarrays. Hierarchical cluster analysis of the genes showing...

Genome-Wide Analysis of the General Stress Response Network in Escherichia coli: σS-Dependent Genes, Promoters, and Sigma Factor Selectivity†

Weber, Harald, Polen, Tino, Heuveling, Johanna, Wendisch, Volker F., Hengge, Regine

The σS (or RpoS) subunit of RNA polymerase is the master regulator of the general stress response in Escherichia coli. While nearly absent in rapidly growing cells, σS is strongly induced during...

Phosphate Starvation-Inducible Gene ushA Encodes a 5′ Nucleotidase Required for Growth of Corynebacterium glutamicum on Media with Nucleotides as the Phosphorus Source

Rittmann, Doris, Sorger-Herrmann, Ulrike, Wendisch, Volker F.

Phosphorus is an essential component of macromolecules, like DNA, and central metabolic intermediates, such as sugar phosphates, and bacteria possess enzymes and control mechanisms that provide an...

Characterization of a Corynebacterium glutamicum Lactate Utilization Operon Induced during Temperature-Triggered Glutamate Production†

Stansen, Corinna, Uy, Davin, Delaunay, Stephane, Eggeling, Lothar, Goergen, Jean-Louis, Wendisch, Volker F.

Gene expression changes of glutamate-producing Corynebacterium glutamicum were identified in transcriptome comparisons by DNA microarray analysis. During glutamate production induced by a temperature...

Two-Component Systems of Corynebacterium glutamicum: Deletion Analysis and Involvement of the PhoS-PhoR System in the Phosphate Starvation Response§

Kočan, Martina, Schaffer, Steffen, Ishige, Takeru, Sorger-Herrmann, Ulrike, Wendisch, Volker F., Bott, Michael

Corynebacterium glutamicum contains genes for 13 two-component signal transduction systems. In order to test for their essentiality and involvement in the adaptive response to phosphate (Pi)...

Nitrogen regulatory protein C-controlled genes of Escherichia coli: Scavenging as a defense against nitrogen limitation

Zimmer, Daniel P., Soupene, Eric, Lee, Haidy L., Wendisch, Volker F., Khodursky, Arkady B., Peter, Brian J., ...

Nitrogen regulatory protein C (NtrC) of enteric bacteria activates transcription of genes/operons whose products minimize the slowing of growth under nitrogen-limiting conditions. To reveal the NtrC...

Quantitative Determination of Metabolic Fluxes during Coutilization of Two Carbon Sources: Comparative Analyses with Corynebacterium glutamicum during Growth on Acetate and/or Glucose†

Wendisch, Volker F., De Graaf, Albert A., Sahm, Hermann, Eikmanns, Bernhard J.

Growth of Corynebacterium glutamicum on mixtures of the carbon sources glucose and acetate is shown to be distinct from growth on either substrate alone. The organism showed nondiauxic growth on...

The Phosphate Starvation Stimulon of Corynebacterium glutamicum Determined by DNA Microarray Analyses

Ishige, Takeru, Krause, Malgorzata, Bott, Michael, Wendisch, Volker F., Sahm, Hermann

The phosphate (Pi) starvation stimulon of Corynebacterium glutamicum was characterized by global gene expression analysis by using DNA microarrays. Hierarchical cluster analysis of the genes showing...

Genome-Wide Analysis of the General Stress Response Network in Escherichia coli: σS-Dependent Genes, Promoters, and Sigma Factor Selectivity†

Weber, Harald, Polen, Tino, Heuveling, Johanna, Wendisch, Volker F., Hengge, Regine

The σS (or RpoS) subunit of RNA polymerase is the master regulator of the general stress response in Escherichia coli. While nearly absent in rapidly growing cells, σS is strongly induced during...

Phosphate Starvation-Inducible Gene ushA Encodes a 5′ Nucleotidase Required for Growth of Corynebacterium glutamicum on Media with Nucleotides as the Phosphorus Source

Rittmann, Doris, Sorger-Herrmann, Ulrike, Wendisch, Volker F.

Phosphorus is an essential component of macromolecules, like DNA, and central metabolic intermediates, such as sugar phosphates, and bacteria possess enzymes and control mechanisms that provide an...

Characterization of a Corynebacterium glutamicum Lactate Utilization Operon Induced during Temperature-Triggered Glutamate Production†

Stansen, Corinna, Uy, Davin, Delaunay, Stephane, Eggeling, Lothar, Goergen, Jean-Louis, Wendisch, Volker F.

Gene expression changes of glutamate-producing Corynebacterium glutamicum were identified in transcriptome comparisons by DNA microarray analysis. During glutamate production induced by a temperature...

Two-Component Systems of Corynebacterium glutamicum: Deletion Analysis and Involvement of the PhoS-PhoR System in the Phosphate Starvation Response§

Kočan, Martina, Schaffer, Steffen, Ishige, Takeru, Sorger-Herrmann, Ulrike, Wendisch, Volker F., Bott, Michael

Corynebacterium glutamicum contains genes for 13 two-component signal transduction systems. In order to test for their essentiality and involvement in the adaptive response to phosphate (Pi)...

Characterization of myo-Inositol Utilization by Corynebacterium glutamicum: the Stimulon, Identification of Transporters, and Influence on l-Lysine Formation▿

Krings, Eva, Krumbach, Karin, Bathe, Brigitte, Kelle, Ralf, Wendisch, Volker F., Sahm, Hermann, ...

Although numerous bacteria possess genes annotated iol in their genomes, there have been very few studies on the possibly associated myo-inositol metabolism and its significance for the cell. We...

The DeoR-Type Regulator SugR Represses Expression of ptsG in Corynebacterium glutamicum▿

Engels, Verena, Wendisch, Volker F.

Corynebacterium glutamicum grows on a variety of carbohydrates and organic acids. Uptake of the preferred carbon source glucose via the phosphoenolpyruvate-dependent phosphotransferase system (PTS)...

NCgl2620 Encodes a Class II Polyphosphate Kinase in Corynebacterium glutamicum▿

Lindner, Steffen N., Vidaurre, Dolores, Willbold, Sabine, Schoberth, Siegfried M., Wendisch, Volker F.

Corynebacterium glutamicum is able to accumulate up to 600 mM cytosolic phosphorus in the form of polyphosphate (poly P). Granular poly P (volutin) can make up to 37% of the internal cell volume....

Gene Expression Analysis of Corynebacterium glutamicum Subjected to Long-Term Lactic Acid Adaptation▿ ¶

Jakob, Kinga, Satorhelyi, Peter, Lange, Christian, Wendisch, Volker F., Silakowski, Barbara, Scherer, Siegfried, ...

Corynebacteria form an important part of the red smear cheese microbial surface consortium. To gain a better understanding of molecular adaptation due to low pH induced by lactose fermentation, the...

Regulation of l-Lactate Utilization by the FadR-Type Regulator LldR of Corynebacterium glutamicum▿

Georgi, Tobias, Engels, Verena, Wendisch, Volker F.

Corynebacterium glutamicum can grow on l-lactate as a sole carbon and energy source. The NCgl2816-lldD operon encoding a putative transporter (NCgl2816) and a quinone-dependent l-lactate...