Vincenzo Coppola

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

Lyons, W. Ernest, Mamounas, Laura A., Ricaurte, George A., Coppola, Vincenzo, Reid, Susan W., Bora, Susan H., ...

Brain-derived neurotrophic factor (BDNF) has trophic effects on serotonergic (5-HT) neurons in the central nervous system. However, the role of endogenous BDNF in the development and function of...

5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

Catalano, Alfonso, Rodilossi, Sabrina, Caprari, Paola, Coppola, Vincenzo, Procopio, Antonio

5-Lipoxygenase (5LO) is involved in the production of leukotrienes and reactive oxygen species (ROS) from arachidonic acid. Its strong activation has been associated with several diseases like cancer...

The Scaffold Protein Cybr Is Required for Cytokine-Modulated Trafficking of Leukocytes In Vivo

Coppola, Vincenzo, Barrick, Colleen A., Bobisse, Sara, Rodriguez-Galan, Maria Cecilia, Pivetta, Michela, Reynolds, Della, ...

Trafficking and cell adhesion are key properties of cells of the immune system. However, the molecular pathways that control these cellular behaviors are still poorly understood. Cybr is a scaffold...

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

Lyons, W. Ernest, Mamounas, Laura A., Ricaurte, George A., Coppola, Vincenzo, Reid, Susan W., Bora, Susan H., ...

Brain-derived neurotrophic factor (BDNF) has trophic effects on serotonergic (5-HT) neurons in the central nervous system. However, the role of endogenous BDNF in the development and function of...

5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

Catalano, Alfonso, Rodilossi, Sabrina, Caprari, Paola, Coppola, Vincenzo, Procopio, Antonio

5-Lipoxygenase (5LO) is involved in the production of leukotrienes and reactive oxygen species (ROS) from arachidonic acid. Its strong activation has been associated with several diseases like cancer...

The Scaffold Protein Cybr Is Required for Cytokine-Modulated Trafficking of Leukocytes In Vivo

Coppola, Vincenzo, Barrick, Colleen A., Bobisse, Sara, Rodriguez-Galan, Maria Cecilia, Pivetta, Michela, Reynolds, Della, ...

Trafficking and cell adhesion are key properties of cells of the immune system. However, the molecular pathways that control these cellular behaviors are still poorly understood. Cybr is a scaffold...

A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin

Esteban, Pedro F., Yoon, Hye-Young, Becker, Jodi, Dorsey, Susan G., Caprari, Paola, Palko, Mary Ellen, ...

Neurotrophins play an essential role in mammalian development. Most of their functions have been attributed to activation of the kinase-active Trk receptors and the p75 neurotrophin receptor....