Larru, Beatriz, De Mendoza, Carmen, Bellón, José, De José, Ma Isabel, Mellado, Ma José, Soriano, Vincent, ...
Abstract Background The impact of HIV drug resistance mutations in salvage therapy has been widely investigated in adults. By contrast, data available of predictive value of resistance mutations in...
Rami Kantor, David A. Katzenstein, Brad Efron, Ana Patricia Carvalho, Brian Wynhoven, Patricia Cane, ...
Most research has focused on HIV-1 subtype B, although most infections worldwide are non-B. However, this paper suggests that the same drug resistance mutations occur across subtypes.
Rami Kantor, David A. Katzenstein, Brad Efron, Ana Patricia Carvalho, Brian Wynhoven, Patricia Cane, ...
Background The genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral treatment is expanded to regions of the world where...
Soriano, Vincent, Mas, Antonio, Arts, Eric J., Heneine, Walid
We have evaluated the use of an ultrasensitive reverse transcriptase (RT) activity assay to monitor plasma viremia in two human immunodeficiency virus type 1 (HIV-1) group O-infected patients treated...
Heredia, Alonso, Soriano, Vincent, Bravo, Rosa, Epstein, Jay S., Hewlett, Indira K.
A method for co-amplification of multiple viral sequences of HIV-1 and HIV-2 by polymerase chain reaction was designed. The technique resulted in the specific detection of each type of virus and...
Rodés, Berta, Holguín, Africa, Soriano, Vincent, Dourana, Manuela, Mansinho, Kamal, Antunes, Francisco, ...
The reverse transcriptase (RT) and protease genes from 12 human immunodeficiency virus type 2 (HIV-2)-infected individuals who had been exposed to antiretroviral drugs for longer than 6 months were...
Swanson, Priscilla, Soriano, Vincent, Devare, Sushil G., Hackett, John
The performance of the LCx HIV RNA Quantitative (LCx HIV), AMPLICOR HIV-1 MONITOR version 1.5 (MONITOR v1.5), and Quantiplex HIV-1 RNA version 3.0 (bDNA v3.0) viral load assays was evaluated with 39...
Holguín, Africa, Aracil, Belén, Álvarez, Amparo, Barros, Carlos, Soriano, Vincent
Plasma specimens collected in 1999 from 32 human immunodeficiency virus type 1 (HIV-1)-infected foreigners living in Madrid, Spain, were examined for the presence of non-B subtypes. Furthermore,...
Lerma, J. Gerardo García, Soriano, Vincent, Mas, Antonio, Quiñones-Mateu, Miguel E., Arts, Eric J., Heneine, Walid
We have evaluated the use of an ultrasensitive reverse transcriptase (RT) activity assay to monitor plasma viremia in two human immunodeficiency virus type 1 (HIV-1) group O-infected patients treated...
García Lerma, J. Gerardo, Schinazi, Raymond F., Juodawlkis, Amy S., Soriano, Vincent, Lin, Yulin, Tatti, Kathleen, ...
Monitoring for lamivudine (3TC) resistance is important both for the clinical management of human immunodeficiency virus type 1 (HIV-1)-infected patients treated with 3TC and for surveillance of...
Gallego, Oscar, Ruíz, Lidia, Vallejo, Alex, Clotet, Bonaventura, Leal, Manuel, Soriano, Vincent
The knowledge of which drug-resistant human immunodeficiency virus (HIV) genotypes are the most prevalent in a community may be helpful for designing the best salvage regimens. A total of 540...
Rodés, Berta, Poveda, Eva, Soriano, Vincent
A bacteriophage lambda-based method was used to investigate the development of resistance to protease inhibitors (PI) in one subject infected with human immunodeficiency virus (HIV) type 1 group O...
De Mendoza, Carmen, Alcamí, José, Sainz, María, Folgueira, Dolores, Soriano, Vincent
Plasma human immunodeficiency virus RNA in 491 clinical specimens was measured by LCx. There was a strong correlation with the results provided by other methods (r2 values of 0.93 with Cobas-Monitor...
Changes in the Human Immunodeficiency Virus p7-p1-p6 gag Gene in Drug-Naive and Pretreated Patients
Gallego, Oscar, De Mendoza, Carmen, Corral, Angélica, Soriano, Vincent
Resistance to antiretroviral agents often results from mutations within the human immunodeficiency virus (HIV) pol gene. Moreover, insertions within the p6 gag-pol region have recently been found to...
Barrios, Ana, De Mendoza, Carmen, Martín-Carbonero, Luz, Ribera, Esteve, Domingo, Pere, Galindo, María José, ...
Human immunodeficiency virus (HIV)-infected patients (n = 153) failing antiretroviral therapy after exposure to compounds from all three drug families were monitored for 6 months after beginning a...
De Mendoza, Carmen, Paxinos, Ellen, Barreiro, Pablo, Camino, Nuria, Núñez, Marina, Soriano, Vincent
A total of 76 patients discontinued treatment with didanosine plus hydroxyurea after 1 year of maintenance therapy. The greatest human immunodeficiency virus (HIV)-RNA rebounds were seen in 10...
Kantor, Rami, Katzenstein, David A, Efron, Brad, Carvalho, Ana Patricia, Wynhoven, Brian, Cane, Patricia, ...
Most research has focused on HIV-1 subtype B, although most infections worldwide are non-B. However, this paper suggests that the same drug resistance mutations occur across subtypes
Swanson, Priscilla, De Mendoza, Carmen, Joshi, Yagnya, Golden, Alan, Hodinka, Richard L., Soriano, Vincent, ...
Human immunodeficiency virus type 1 (HIV-1) evolution and changing strain distribution present a challenge to nucleic acid-based assays. Reliable patient monitoring of viral loads requires the...
Bassani, Sylvina, Toro, Carlos, Jiménez, Victoria, Rodés, Berta, Soriano, Vincent
A total of 175 human immunodeficiency virus (HIV)-positive intravenous drug users (IDU) with CD4 cell counts of 500 cells/μl. Enzyme immunoassay (EIA) reactivity and human T-cell lymphotropic virus...
Snoeck, Joke, Kantor, Rami, Shafer, Robert W., Van Laethem, Kristel, Deforche, Koen, Carvalho, Ana Patricia, ...
The major limitation of drug resistance genotyping for human immunodeficiency virus remains the interpretation of the results. We evaluated the concordance in predicting therapy response between four...
Rodés, Berta, Holguín, Africa, Soriano, Vincent, Dourana, Manuela, Mansinho, Kamal, Antunes, Francisco, ...
The reverse transcriptase (RT) and protease genes from 12 human immunodeficiency virus type 2 (HIV-2)-infected individuals who had been exposed to antiretroviral drugs for longer than 6 months were...
Swanson, Priscilla, Soriano, Vincent, Devare, Sushil G., Hackett, John
The performance of the LCx HIV RNA Quantitative (LCx HIV), AMPLICOR HIV-1 MONITOR version 1.5 (MONITOR v1.5), and Quantiplex HIV-1 RNA version 3.0 (bDNA v3.0) viral load assays was evaluated with 39...
Holguín, Africa, Aracil, Belén, Álvarez, Amparo, Barros, Carlos, Soriano, Vincent
Plasma specimens collected in 1999 from 32 human immunodeficiency virus type 1 (HIV-1)-infected foreigners living in Madrid, Spain, were examined for the presence of non-B subtypes. Furthermore,...
Lerma, J. Gerardo García, Soriano, Vincent, Mas, Antonio, Quiñones-Mateu, Miguel E., Arts, Eric J., Heneine, Walid
We have evaluated the use of an ultrasensitive reverse transcriptase (RT) activity assay to monitor plasma viremia in two human immunodeficiency virus type 1 (HIV-1) group O-infected patients treated...
García Lerma, J. Gerardo, Schinazi, Raymond F., Juodawlkis, Amy S., Soriano, Vincent, Lin, Yulin, Tatti, Kathleen, ...
Monitoring for lamivudine (3TC) resistance is important both for the clinical management of human immunodeficiency virus type 1 (HIV-1)-infected patients treated with 3TC and for surveillance of...
Gallego, Oscar, Ruíz, Lidia, Vallejo, Alex, Clotet, Bonaventura, Leal, Manuel, Soriano, Vincent
The knowledge of which drug-resistant human immunodeficiency virus (HIV) genotypes are the most prevalent in a community may be helpful for designing the best salvage regimens. A total of 540...
Rodés, Berta, Poveda, Eva, Soriano, Vincent
A bacteriophage lambda-based method was used to investigate the development of resistance to protease inhibitors (PI) in one subject infected with human immunodeficiency virus (HIV) type 1 group O...
De Mendoza, Carmen, Alcamí, José, Sainz, María, Folgueira, Dolores, Soriano, Vincent
Plasma human immunodeficiency virus RNA in 491 clinical specimens was measured by LCx. There was a strong correlation with the results provided by other methods (r2 values of 0.93 with Cobas-Monitor...
Changes in the Human Immunodeficiency Virus p7-p1-p6 gag Gene in Drug-Naive and Pretreated Patients
Gallego, Oscar, De Mendoza, Carmen, Corral, Angélica, Soriano, Vincent
Resistance to antiretroviral agents often results from mutations within the human immunodeficiency virus (HIV) pol gene. Moreover, insertions within the p6 gag-pol region have recently been found to...
Barrios, Ana, De Mendoza, Carmen, Martín-Carbonero, Luz, Ribera, Esteve, Domingo, Pere, Galindo, María José, ...
Human immunodeficiency virus (HIV)-infected patients (n = 153) failing antiretroviral therapy after exposure to compounds from all three drug families were monitored for 6 months after beginning a...
De Mendoza, Carmen, Paxinos, Ellen, Barreiro, Pablo, Camino, Nuria, Núñez, Marina, Soriano, Vincent
A total of 76 patients discontinued treatment with didanosine plus hydroxyurea after 1 year of maintenance therapy. The greatest human immunodeficiency virus (HIV)-RNA rebounds were seen in 10...
Kantor, Rami, Katzenstein, David A, Efron, Brad, Carvalho, Ana Patricia, Wynhoven, Brian, Cane, Patricia, ...
Most research has focused on HIV-1 subtype B, although most infections worldwide are non-B. However, this paper suggests that the same drug resistance mutations occur across subtypes
Swanson, Priscilla, De Mendoza, Carmen, Joshi, Yagnya, Golden, Alan, Hodinka, Richard L., Soriano, Vincent, ...
Human immunodeficiency virus type 1 (HIV-1) evolution and changing strain distribution present a challenge to nucleic acid-based assays. Reliable patient monitoring of viral loads requires the...
Bassani, Sylvina, Toro, Carlos, Jiménez, Victoria, Rodés, Berta, Soriano, Vincent
A total of 175 human immunodeficiency virus (HIV)-positive intravenous drug users (IDU) with CD4 cell counts of 500 cells/μl. Enzyme immunoassay (EIA) reactivity and human T-cell lymphotropic virus...
Snoeck, Joke, Kantor, Rami, Shafer, Robert W., Van Laethem, Kristel, Deforche, Koen, Carvalho, Ana Patricia, ...
The major limitation of drug resistance genotyping for human immunodeficiency virus remains the interpretation of the results. We evaluated the concordance in predicting therapy response between four...
Rodés, Berta, Sheldon, Julie, Toro, Carlos, Cuevas, Laureano, Pérez-Pastrana, Esperanza, Herrera, Inmaculada, ...
No commercial viral load assay has yet been approved for use for measurement of human immunodeficiency virus type 2 (HIV-2) RNA levels in plasma. We assessed the performance of the NucliSens EasyQ...
Larru, Beatriz, De Mendoza, Carmen, Bellón, José Ma, De José, Ma Isabel, Mellado, Ma José, Soriano, Vincent, ...
Garrido, Carolina, Roulet, Vanessa, Chueca, Natalia, Poveda, Eva, Aguilera, Antonio, Skrabal, Katharina, ...
Human immunodeficiency virus type 1 (HIV-1) tropism can be assessed using phenotypic assays, but this is quite laborious, expensive, and time-consuming and can be made only in sophisticated...