Vincent Lambert

Matrix Metalloproteinase-9 Contributes to Choroidal Neovascularization

Lambert, Vincent, Munaut, Carine, Jost, Maud, Noël, Agnès, Werb, Zena, Foidart, Jean-Michel, ...

Age-related macular degeneration (AMD) is the primary cause of irreversible photoreceptors loss in adult patients and current therapies are limited. Increased levels of matrix metalloproteinases...

Tumoral and Choroidal Vascularization : Differential Cellular Mechanisms Involving Plasminogen Activator Inhibitor Type I

Jost, Maud, Maillard, Catherine, Lecomte, Julie, Lambert, Vincent, Tjwa, Marc, Blaise, Pierre, ...

An adequate balance between serine proteases and their plasminogen activator inhibitor-1 (PAI-1) is critical for pathological angiogenesis. PAI-1 deficiency in mice is associated with impaired...