Effective Post-Exposure Treatment of Ebola Infection (2007)
Heinz Feldmann, Steven M. Jones, Joan B. Geisbert, Ute Ströher, Allen Grolla, ...
Ebola viruses are highly lethal human pathogens that have received considerable attention in recent years due to an increasing re-emergence in Central Africa and a potential for use as a biological...
Development of a New Vaccine for the Prevention of Lassa Fever (2005)
Thomas W. Geisbert, Steven Jones, Elizabeth A. Fritz, Amy C. Shurtleff, Joan B. Geisbert, Ryan Liebscher, ...
A replication-competent vaccine based on attenuated recombinant vesicular stomatitis virus vector protects non- human primates.
Development of a New Vaccine for the Prevention of Lassa Fever (2005)
Thomas W. Geisbert, Steven Jones, Elizabeth A. Fritz, Amy C. Shurtleff, Joan B. Geisbert, Ryan Liebscher, ...
Background Recent importation of Lassa fever into Germany, the Netherlands, the United Kingdom, and the United States by travelers on commercial airlines from Africa underscores the public health...
Infection and Activation of Monocytes by Marburg and Ebola Viruses
Ströher, Ute, West, Elmar, Bugany, Harald, Klenk, Hans-Dieter, Schnittler, Hans-Joachim, Feldmann, Heinz
In this study we investigated the effects of Marburg virus and Ebola virus (species Zaire and Reston) infections on freshly isolated suspended monocytes in comparison to adherent macrophages under...
Garbutt, Michael, Liebscher, Ryan, Wahl-Jensen, Victoria, Jones, Steven, Möller, Peggy, Wagner, Ralf, ...
Replication-competent recombinant vesicular stomatitis viruses (rVSVs) expressing the type I transmembrane glycoproteins and selected soluble glycoproteins of several viral hemorrhagic fever agents...
Ectodomain shedding of the glycoprotein GP of Ebola virus
Dolnik, Olga, Volchkova, Valentina, Garten, Wolfgang, Carbonnelle, Caroline, Becker, Stephan, Kahnt, Jörg, ...
In this study, release of abundant amounts of the Ebola virus (EBOV) surface glycoprotein GP in a soluble form from virus-infected cells was investigated. We demonstrate that the mechanism...
Wahl-Jensen, Victoria, Kurz, Sabine K., Hazelton, Paul R., Schnittler, Hans-Joachim, Ströher, Ute, Burton, Dennis R., ...
Ebola virus, a member of the family Filoviridae, causes one of the most severe forms of viral hemorrhagic fever. In the terminal stages of disease, symptoms progress to hypotension, coagulation...
Development of a New Vaccine for the Prevention of Lassa Fever
Geisbert, Thomas W, Jones, Steven, Fritz, Elizabeth A, Shurtleff, Amy C, Geisbert, Joan B, Liebscher, Ryan, ...
A replication-competent vaccine based on attenuated recombinant vesicular stomatitis virus vector protects non- human primates.
Effects of Ebola Virus Glycoproteins on Endothelial Cell Activation and Barrier Function
Wahl-Jensen, Victoria M., Afanasieva, Tatiana A., Seebach, Jochen, Ströher, Ute, Feldmann, Heinz, Schnittler, Hans-Joachim
Ebola virus causes severe hemorrhagic fever with high mortality rates in humans and nonhuman primates. Vascular instability and dysregulation are disease-decisive symptoms during severe infection....
Marburgvirus Genomics and Association with a Large Hemorrhagic Fever Outbreak in Angola
Towner, Jonathan S., Khristova, Marina L., Sealy, Tara K., Vincent, Martin J., Erickson, Bobbie R., Bawiec, Darcy A., ...
In March 2005, the Centers for Disease Control and Prevention (CDC) investigated a large hemorrhagic fever (HF) outbreak in Uige Province in northern Angola, West Africa. In total, 15 initial...
Hoenen, Thomas, Groseth, Allison, Kolesnikova, Larissa, Theriault, Steven, Ebihara, Hideki, Hartlieb, Bettina, ...
Infectious virus-like particle (iVLP) systems have recently been established for several negative-strand RNA viruses, including the highly pathogenic Zaire ebolavirus (ZEBOV), and allow study of the...
Infection and Activation of Monocytes by Marburg and Ebola Viruses
Ströher, Ute, West, Elmar, Bugany, Harald, Klenk, Hans-Dieter, Schnittler, Hans-Joachim, Feldmann, Heinz
In this study we investigated the effects of Marburg virus and Ebola virus (species Zaire and Reston) infections on freshly isolated suspended monocytes in comparison to adherent macrophages under...
Garbutt, Michael, Liebscher, Ryan, Wahl-Jensen, Victoria, Jones, Steven, Möller, Peggy, Wagner, Ralf, ...
Replication-competent recombinant vesicular stomatitis viruses (rVSVs) expressing the type I transmembrane glycoproteins and selected soluble glycoproteins of several viral hemorrhagic fever agents...
Ectodomain shedding of the glycoprotein GP of Ebola virus
Dolnik, Olga, Volchkova, Valentina, Garten, Wolfgang, Carbonnelle, Caroline, Becker, Stephan, Kahnt, Jörg, ...
In this study, release of abundant amounts of the Ebola virus (EBOV) surface glycoprotein GP in a soluble form from virus-infected cells was investigated. We demonstrate that the mechanism...
Wahl-Jensen, Victoria, Kurz, Sabine K., Hazelton, Paul R., Schnittler, Hans-Joachim, Ströher, Ute, Burton, Dennis R., ...
Ebola virus, a member of the family Filoviridae, causes one of the most severe forms of viral hemorrhagic fever. In the terminal stages of disease, symptoms progress to hypotension, coagulation...
Development of a New Vaccine for the Prevention of Lassa Fever
Geisbert, Thomas W, Jones, Steven, Fritz, Elizabeth A, Shurtleff, Amy C, Geisbert, Joan B, Liebscher, Ryan, ...
A replication-competent vaccine based on attenuated recombinant vesicular stomatitis virus vector protects non- human primates.
Effects of Ebola Virus Glycoproteins on Endothelial Cell Activation and Barrier Function
Wahl-Jensen, Victoria M., Afanasieva, Tatiana A., Seebach, Jochen, Ströher, Ute, Feldmann, Heinz, Schnittler, Hans-Joachim
Ebola virus causes severe hemorrhagic fever with high mortality rates in humans and nonhuman primates. Vascular instability and dysregulation are disease-decisive symptoms during severe infection....
Marburgvirus Genomics and Association with a Large Hemorrhagic Fever Outbreak in Angola
Towner, Jonathan S., Khristova, Marina L., Sealy, Tara K., Vincent, Martin J., Erickson, Bobbie R., Bawiec, Darcy A., ...
In March 2005, the Centers for Disease Control and Prevention (CDC) investigated a large hemorrhagic fever (HF) outbreak in Uige Province in northern Angola, West Africa. In total, 15 initial...
Hoenen, Thomas, Groseth, Allison, Kolesnikova, Larissa, Theriault, Steven, Ebihara, Hideki, Hartlieb, Bettina, ...
Infectious virus-like particle (iVLP) systems have recently been established for several negative-strand RNA viruses, including the highly pathogenic Zaire ebolavirus (ZEBOV), and allow study of the...
Effective Post-Exposure Treatment of Ebola Infection
Feldmann, Heinz, Jones, Steven M, Daddario-DiCaprio, Kathleen M, Geisbert, Joan B, Ströher, Ute, Grolla, Allen, ...
Ebola viruses are highly lethal human pathogens that have received considerable attention in recent years due to an increasing re-emergence in Central Africa and a potential for use as a biological...
Cross-Protection against Marburg Virus Strains by Using a Live, Attenuated Recombinant Vaccine
Daddario-DiCaprio, Kathleen M., Geisbert, Thomas W., Geisbert, Joan B., Ströher, Ute, Hensley, Lisa E., Grolla, Allen, ...
Marburg virus (MARV) has been associated with sporadic episodes of hemorrhagic fever, including a recent highly publicized outbreak in Angola that produced severe disease and significant mortality in...