Ulrike Schulte-Spechtel

Comparative genome analysis: selection pressure on the Borrelia vlscassettes is essential for infectivity (2006)

Glöckner, Gernot, Schulte-Spechtel, Ulrike, Schilhabel, Markus, Felder, Marius, Sühnel, Jürgen, Wilske, Bettina, ...

Abstract Background At least three species of Borrelia burgdorferi sensu lato (Bbsl) cause tick-borne Lyme disease. Previous work including the genome analysis of B. burgdorferi B31 and B. garinii...

Dynamics of Dissemination and Outer Surface Protein Expression of Different European Borrelia burgdorferi Sensu Lato Strains in Artificially Infected Ixodes ricinus Nymphs

Fingerle, Volker, Rauser, Sandra, Hammer, Bettina, Kahl, Olaf, Heimerl, Christiane, Schulte-Spechtel, Ulrike, ...

Unfed Ixodes ricinus nymphs were infected with eight different strains and clones of Borrelia afzelii and B. garinii by capillary feeding. Except one B. afzelii clone, all expressed OspC in culture....

Significant Improvement of the Recombinant Borrelia-Specific Immunoglobulin G Immunoblot Test by Addition of VlsE and a DbpA Homologue Derived from Borrelia garinii for Diagnosis of Early Neuroborreliosis

Schulte-Spechtel, Ulrike, Lehnert, Gisela, Liegl, Gaby, Fingerle, Volker, Heimerl, Christiane, Johnson, Barbara J. B., ...

We investigated whether the recombinant Borrelia Western blot test previously described (B. Wilske, C. Habermann, V. Fingerle, B. Hillenbrand, S. Jauris-Heipke, G. Lehnert, I. Pradel, D. Rössler,...

Improvement of Lyme Borreliosis Serodiagnosis by a Newly Developed Recombinant Immunoglobulin G (IgG) and IgM Line Immunoblot Assay and Addition of VlsE and DbpA Homologues

Goettner, Gereon, Schulte-Spechtel, Ulrike, Hillermann, Ruth, Liegl, Gabi, Wilske, Bettina, Fingerle, Volker

We developed and evaluated a recombinant Borrelia line immunoblot assay based on 18 homologues of seven different antigens, i.e., p100, p58, p41i, BmpA, VlsE, OspC, and DbpA. Each recombinant antigen...

Dynamics of Dissemination and Outer Surface Protein Expression of Different European Borrelia burgdorferi Sensu Lato Strains in Artificially Infected Ixodes ricinus Nymphs

Fingerle, Volker, Rauser, Sandra, Hammer, Bettina, Kahl, Olaf, Heimerl, Christiane, Schulte-Spechtel, Ulrike, ...

Unfed Ixodes ricinus nymphs were infected with eight different strains and clones of Borrelia afzelii and B. garinii by capillary feeding. Except one B. afzelii clone, all expressed OspC in culture....

Significant Improvement of the Recombinant Borrelia-Specific Immunoglobulin G Immunoblot Test by Addition of VlsE and a DbpA Homologue Derived from Borrelia garinii for Diagnosis of Early Neuroborreliosis

Schulte-Spechtel, Ulrike, Lehnert, Gisela, Liegl, Gaby, Fingerle, Volker, Heimerl, Christiane, Johnson, Barbara J. B., ...

We investigated whether the recombinant Borrelia Western blot test previously described (B. Wilske, C. Habermann, V. Fingerle, B. Hillenbrand, S. Jauris-Heipke, G. Lehnert, I. Pradel, D. Rössler,...

Improvement of Lyme Borreliosis Serodiagnosis by a Newly Developed Recombinant Immunoglobulin G (IgG) and IgM Line Immunoblot Assay and Addition of VlsE and DbpA Homologues

Goettner, Gereon, Schulte-Spechtel, Ulrike, Hillermann, Ruth, Liegl, Gabi, Wilske, Bettina, Fingerle, Volker

We developed and evaluated a recombinant Borrelia line immunoblot assay based on 18 homologues of seven different antigens, i.e., p100, p58, p41i, BmpA, VlsE, OspC, and DbpA. Each recombinant antigen...

Human Pathogenic Borrelia spielmanii sp. nov. Resists Complement-Mediated Killing by Direct Binding of Immune Regulators Factor H and Factor H-Like Protein 1▿

Herzberger, Pia, Siegel, Corinna, Skerka, Christine, Fingerle, Volker, Schulte-Spechtel, Ulrike, Van Dam, Alje, ...

Borrelia spielmanii sp. nov. has recently been shown to be a novel human pathogenic genospecies that causes Lyme disease in Europe. In order to elucidate the immune evasion mechanisms of B....