Torben R. Neelands

Acidification of rat TRPV1 alters the kinetics of capsaicin responses (2005)

Neelands, Torben R, Jarvis, Michael F, Han, Ping, Faltynek, Connie R, Surowy, Carol S

Abstract TRPV1 (vanilloid receptor 1) receptors are activated by a variety of ligands such as capsaicin, as well as by acidic conditions and temperatures above 42°C. These activators can enhance the...

Acidification of rat TRPV1 alters the kinetics of capsaicin responses

Neelands, Torben R, Jarvis, Michael F, Han, Ping, Faltynek, Connie R, Surowy, Carol S

TRPV1 (vanilloid receptor 1) receptors are activated by a variety of ligands such as capsaicin, as well as by acidic conditions and temperatures above 42°C. These activators can enhance the potency...

Acidification of rat TRPV1 alters the kinetics of capsaicin responses

Neelands, Torben R, Jarvis, Michael F, Han, Ping, Faltynek, Connie R, Surowy, Carol S

TRPV1 (vanilloid receptor 1) receptors are activated by a variety of ligands such as capsaicin, as well as by acidic conditions and temperatures above 42°C. These activators can enhance the potency...

2′, 3′-O-(2,4,6,Trinitrophenyl)-ATP and A-317491 are competitive antagonists at a slowly desensitizing chimeric human P2X3 receptor

Neelands, Torben R, Burgard, Edward C, Uchic, Marie E, McDonald, Heath A, Niforatos, Wende, Faltynek, Connie R, ...

Rapid desensitization of ligand-gated ion channel receptors can alter the apparent activity of receptor modulators, as well as make detection of fast-channel activation difficult. Investigation of...

Small-conductance calcium-activated potassium currents in mouse hyperexcitable denervated skeletal muscle

Neelands, Torben R, Herson, Paco S, Jacobson, David, Adelman, John P, Maylie, James

Hyperexcitability in denervated skeletal muscle is associated with the expression of SK3, a small-conductance Ca2+-activated K+ channel (SK channel). SK currents were examined in dissociated fibres...