Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD (2008)
Knowles, Joshua W, Assimes, Themistocles L, Boerwinkle, Eric, Fortmann, Stephen P, Go, Alan, Grove, Megan L, ...
Abstract Background The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1 ) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with...
Kraja, Aldi T, Rao, DC, Weder, Alan B, Mosley, Thomas H, Turner, Stephen T, Hsiung, Chao, ...
Abstract Background The Family Blood Pressure Program is an ongoing, NHLBI-sponsored, multi-center program to study the genetic determinants of high blood pressure. The goal of this particular study...
Bray, Robert A., Kornbluth, Jacki, Landay, Alan L., Strominger, Jack L., Gebel, Howard, Seidman, Jon G., ...
To test the hypothesis that the T-cell receptor ( Tcr ) λ gene encodes a natural killer (NK) cell receptor molecule, three human NK clones and fresh peripheral blood lymphocytes with NK activity...
Endothelial lipase is a major determinant of HDL level
Ishida, Tatsuro, Choi, Sungshin, Kundu, Ramendra K., Hirata, Ken-ichi, Rubin, Edward M., Cooper, Allen D., ...
A new member of the lipase gene family, initially termed endothelial lipase (gene nomenclature, LIPG; protein, EL), is expressed in a variety of different tissues, suggesting a general role in lipid...
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1
Zhong, Jingping, Eliceiri, Brian, Stupack, Dwayne, Penta, Kalyani, Sakamoto, Gordon, Quertermous, Thomas, ...
The ECM protein Del-1 is one of several novel ECM proteins that accumulate around angiogenic blood vessels in embryonic and tumor tissue and promote angiogenesis in the absence of exogenous growth...
Tree-structured supervised learning and the genetics of hypertension
Huang, Jing, Lin, Alfred, Narasimhan, Balasubramanian, Quertermous, Thomas, Hsiung, C. Agnes, Ho, Low-Tone, ...
This paper is about an algorithm, FlexTree, for general supervised learning. It extends the binary tree-structured approach (Classification and Regression Trees, CART) although it differs greatly in...
Hidai, Chiaki, Zupancic, Thomas, Penta, Kalyani, Mikhail, Adel, Kawana, Masatoshi, Quertermous, Elena E., ...
We have taken advantage of an enhancer trap event in a line of transgenic mice to identify a unique developmentally regulated endothelial cell locus (Del1). The protein encoded in this locus contains...
Endothelial lipase is a major determinant of HDL level
Ishida, Tatsuro, Choi, Sungshin, Kundu, Ramendra K., Hirata, Ken-ichi, Rubin, Edward M., Cooper, Allen D., ...
A new member of the lipase gene family, initially termed endothelial lipase (gene nomenclature, LIPG; protein, EL), is expressed in a variety of different tissues, suggesting a general role in lipid...
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1
Zhong, Jingping, Eliceiri, Brian, Stupack, Dwayne, Penta, Kalyani, Sakamoto, Gordon, Quertermous, Thomas, ...
The ECM protein Del-1 is one of several novel ECM proteins that accumulate around angiogenic blood vessels in embryonic and tumor tissue and promote angiogenesis in the absence of exogenous growth...
Tree-structured supervised learning and the genetics of hypertension
Huang, Jing, Lin, Alfred, Narasimhan, Balasubramanian, Quertermous, Thomas, Hsiung, C. Agnes, Ho, Low-Tone, ...
This paper is about an algorithm, FlexTree, for general supervised learning. It extends the binary tree-structured approach (Classification and Regression Trees, CART) although it differs greatly in...
Hidai, Chiaki, Zupancic, Thomas, Penta, Kalyani, Mikhail, Adel, Kawana, Masatoshi, Quertermous, Elena E., ...
We have taken advantage of an enhancer trap event in a line of transgenic mice to identify a unique developmentally regulated endothelial cell locus (Del1). The protein encoded in this locus contains...
Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD
Knowles, Joshua W, Assimes, Themistocles L, Boerwinkle, Eric, Fortmann, Stephen P, Go, Alan, Grove, Megan L, ...
Wilson, Kitchener D., Li, Zongjin, Wagner, Roger, Yue, Patrick, Tsao, Phillip, Nestorova, Gergana, ...
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
Chun, Hyung J., Ali, Ziad A., Kojima, Yoko, Kundu, Ramendra K., Sheikh, Ahmad Y., Agrawal, Rani, ...
Apelin and its cognate G protein–coupled receptor APJ constitute a signaling pathway with a positive inotropic effect on cardiac function and a vasodepressor function in the systemic circulation....