Butt, Alison J, Sergio, C Marcelo, Inman, Claire K, Anderson, Luke R, McNeil, Catriona M, Russell, Amanda J, ...
Abstract Introduction Estrogens play a pivotal role in the initiation and progression of breast cancer. The genes that mediate these processes are not fully defined, but potentially include the known...
The ins and outs of translation (2007)
Clancy, Jennifer L, Nousch, Marco, Rodnina, Marina, Preiss, Thomas
A report on the 2nd EMBO Conference on Protein Synthesis and Translational Control, Heidelberg, Germany, 12-16 September 2007.
Functional genomics: strict tempo and hierarchical vocabularies (2004)
A report on the Comparative and Functional Genomics Workshop, Hinxton, UK, 2-5 November 2003.
Thesis (Ph. D.)--University of Newcastle upon Tyne, 1995.
Düsseldorf, Univ., Diss. : 1983.
Hemmings-Mieszczak, Maja, Hohn, Thomas, Preiss, Thomas
We have shown recently that a stable hairpin preceded by a short upstream open reading frame (uORF) promotes nonlinear ribosome migration or ribosome shunt on a synthetic mRNA leader (M....
Yeast 18S rRNA Dimethylase Dim1p: a Quality Control Mechanism in Ribosome Synthesis?
Lafontaine, Denis L. J., Preiss, Thomas, Tollervey, David
One of the few rRNA modifications conserved between bacteria and eukaryotes is the base dimethylation present at the 3′ end of the small subunit rRNA. In the yeast Saccharomyces cerevisiae, this...
Functional genomics: strict tempo and hierarchical vocabularies
A report on the Comparative and Functional Genomics Workshop, Hinxton, UK, 2-5 November 2003.
The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast
BARON-BENHAMOU, JULIE, FORTES, PURI, INADA, TOSHIFUMI, PREISS, THOMAS, HENTZE, MATTHIAS W.
In eukaryotes, the m7GpppN cap structure is added to all nascent RNA polymerase II transcripts, and serves important functions at multiple steps of RNA metabolism. The predominantly nuclear...
WESTMAN, BELINDA, BEEREN, LISA, GRUDZIEN, EWA, STEPINSKI, JANUSZ, WORCH, REMIGIUSZ, ZUBEREK, JOANNA, ...
The eukaryotic initiation factor eIF4E binds the mRNA 5′ cap structure and has a central role during translational initiation. eIF4E and the mechanisms to control its activity have oncogenic...
Humphreys, David T., Westman, Belinda J., Martin, David I. K., Preiss, Thomas
MicroRNAs (miRNAs) repress translation of target mRNAs by interaction with partially mismatched sequences in their 3′ UTR. The mechanism by which they act on translation has remained largely...
Hemmings-Mieszczak, Maja, Hohn, Thomas, Preiss, Thomas
We have shown recently that a stable hairpin preceded by a short upstream open reading frame (uORF) promotes nonlinear ribosome migration or ribosome shunt on a synthetic mRNA leader (M....
Yeast 18S rRNA Dimethylase Dim1p: a Quality Control Mechanism in Ribosome Synthesis?
Lafontaine, Denis L. J., Preiss, Thomas, Tollervey, David
One of the few rRNA modifications conserved between bacteria and eukaryotes is the base dimethylation present at the 3′ end of the small subunit rRNA. In the yeast Saccharomyces cerevisiae, this...
Functional genomics: strict tempo and hierarchical vocabularies
A report on the Comparative and Functional Genomics Workshop, Hinxton, UK, 2-5 November 2003.
Humphreys, David T., Westman, Belinda J., Martin, David I. K., Preiss, Thomas
MicroRNAs (miRNAs) repress translation of target mRNAs by interaction with partially mismatched sequences in their 3′ UTR. The mechanism by which they act on translation has remained largely...
The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast
BARON-BENHAMOU, JULIE, FORTES, PURI, INADA, TOSHIFUMI, PREISS, THOMAS, HENTZE, MATTHIAS W.
In eukaryotes, the m7GpppN cap structure is added to all nascent RNA polymerase II transcripts, and serves important functions at multiple steps of RNA metabolism. The predominantly nuclear...
WESTMAN, BELINDA, BEEREN, LISA, GRUDZIEN, EWA, STEPINSKI, JANUSZ, WORCH, REMIGIUSZ, ZUBEREK, JOANNA, ...
The eukaryotic initiation factor eIF4E binds the mRNA 5′ cap structure and has a central role during translational initiation. eIF4E and the mechanisms to control its activity have oncogenic...
A Network of Multiple Regulatory Layers Shapes Gene Expression in Fission Yeast
Lackner, Daniel H., Beilharz, Traude H., Marguerat, Samuel, Mata, Juan, Watt, Stephen, Schubert, Falk, ...
Gene expression is controlled at multiple layers, and cells may integrate different regulatory steps for coherent production of proper protein levels. We applied various microarray-based approaches...
The eIF4G–homolog p97 can activate translation independent of caspase cleavage
Nousch, Marco, Reed, Victoria, Bryson-Richardson, Robert J., Currie, Peter D., Preiss, Thomas
The eukaryotic initiation factor (eIF) 4G family plays a central role during translation initiation, bridging between the 5′ and 3′ ends of the mRNA via its N-terminal third while recruiting...
Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome
Beilharz, Traude H., Preiss, Thomas
Control of poly(A) tail length can affect translation and stability of eukaryotic mRNAs. Although well established for individual cases, it was not known to what extent this type of adjustable gene...
The ins and outs of translation
Clancy, Jennifer L, Nousch, Marco, Rodnina, Marina, Preiss, Thomas
A report on the 2nd EMBO Conference on Protein Synthesis and Translational Control, Heidelberg, Germany, 12-16 September 2007.