Thierry Baron

A C-terminal protease-resistant prion fragment distinguishes ovine "CH1641-like" scrapie from bovine classical and L-type BSE in ovine transgenic mice (2008)

Baron, Thierry, Bencsik, Anna, Vulin, Johann, Biacabe, Anne-Gaëlle, Morignat, Eric, Verchere, Jérémy, ...

The protease-resistant prion protein (PrPres) of a few natural scrapie isolates identified in sheep, reminiscent of the experimental isolate CH1641 derived from a British natural scrapie case, showed...

A C-terminal protease-resistant prion fragment distinguishes ovine "CH1641-like" scrapie from bovine classical and L-type BSE in ovine transgenic mice (2008)

Baron, Thierry, Bencsik, Anna, Vulin, Johann, Biacabe, Anne-Gaëlle, Morignat, Eric, Verchere, Jérémy, ...

The protease-resistant prion protein (PrPres) of a few natural scrapie isolates identified in sheep, reminiscent of the experimental isolate CH1641 derived from a British natural scrapie case, showed...

Isolation from Cattle of a Prion Strain Distinct from That Causing Bovine Spongiform Encephalopathy (2006)

Vincent Béringue, Anna Bencsik, Annick Le Dur, Fabienne Reine, Thanh Lan Laï, Nathalie Chenais, ...

To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain. This strain is characterised by a unique...

Structuration d'image par utilisation de groupements perceptuels pertinents (1991)

BARON, Thierry, BRIOT, Maurice

En robotique la problématique de la structuration d'image s'inscrit dans le contexte de l'interprétation de scène à partir de primitives images plus ou moins complexes. Les primitives sur...

Etude pour l'utilisation de caméras mono-CCD couleur en robotique (1991)

BARON, Thierry, BRIOT, Maurice

De nos jours, nombre de capteurs sont utilisé pour les tâches de perception en robotique. Nous montrons dans cette communication comment la modélisation de caméras achrome ou couleur peut...

Efficient Transmission of Two Different Sheep Scrapie Isolates in Transgenic Mice Expressing the Ovine PrP Gene

Crozet, Carole, Flamant, Frederic, Bencsik, Anna, Aubert, Denise, Samarut, Jacques, Baron, Thierry

We produced transgenic mice expressing the sheep prion protein to obtain a sensitive model for sheep spongiform encephalopathies (scrapie). The complete open reading frame, with alanine, arginine,...

Comparative Molecular Analysis of the Abnormal Prion Protein in Field Scrapie Cases and Experimental Bovine Spongiform Encephalopathy in Sheep by Use of Western Blotting and Immunohistochemical Methods

Lezmi, Stéphane, Martin, Stuart, Simon, Stéphanie, Comoy, Emmanuel, Bencsik, Anna, Deslys, Jean-Philippe, ...

Since the appearance of bovine spongiform encephalopathy (BSE) in cattle and its linkage with the human variant of Creutzfeldt-Jakob disease, the possible spread of this agent to sheep flocks has...

Molecular Analysis of the Protease-Resistant Prion Protein in Scrapie and Bovine Spongiform Encephalopathy Transmitted to Ovine Transgenic and Wild-Type Mice

Baron, Thierry, Crozet, Carole, Biacabe, Anne-Gaëlle, Philippe, Sandrine, Verchere, Jérémie, Bencsik, Anna, ...

The existence of different strains of infectious agents involved in scrapie, a transmissible spongiform encephalopathy (TSE) of sheep and goats, remains poorly explained. These strains can, however,...

Florid plaques in ovine PrP transgenic mice infected with an experimental ovine BSE

Crozet, Carole, Bencsik, Anna, Flamant, Frédéric, Lezmi, Stéphane, Samarut, Jacques, Baron, Thierry

The occurrence of the variant Creutzfeldt–Jakob disease (vCJD), related to bovine spongiform encephalopathy (BSE), raises the important question of the sources of human contamination. The...

Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein.

Thackray, Alana M, Madec, Jean-Yves, Wong, Edmond, Morgan-Warren, Robert, Brown, David R, Baron, Thierry, ...

Prion-related protein (PrP) is a glycosylphosphatidylinositol-linked cell-surface protein expressed by a wide variety of cells, including those of the nervous system and the immune system. Several...

Distinct molecular phenotypes in bovine prion diseases

Biacabe, Anne-Gaëlle, Laplanche, Jean-Louis, Ryder, Stephen, Baron, Thierry

Bovine spongiform encephalopathy (BSE) in cattle, the most likely cause of variant Creutzfeldt–Jakob disease in humans, is thought to be caused by a unique infectious agent, with stable features,...

A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes

Le Dur, Annick, Béringue, Vincent, Andréoletti, Olivier, Reine, Fabienne, Laï, Thanh Lan, Baron, Thierry, ...

Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can...

Isolation from Cattle of a Prion Strain Distinct from That Causing Bovine Spongiform Encephalopathy

Béringue, Vincent, Bencsik, Anna, Le Dur, Annick, Reine, Fabienne, Laï, Thanh Lan, Chenais, Nathalie, ...

To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain. This strain is characterised by a unique...

Efficient Transmission of Two Different Sheep Scrapie Isolates in Transgenic Mice Expressing the Ovine PrP Gene

Crozet, Carole, Flamant, Frederic, Bencsik, Anna, Aubert, Denise, Samarut, Jacques, Baron, Thierry

We produced transgenic mice expressing the sheep prion protein to obtain a sensitive model for sheep spongiform encephalopathies (scrapie). The complete open reading frame, with alanine, arginine,...

Comparative Molecular Analysis of the Abnormal Prion Protein in Field Scrapie Cases and Experimental Bovine Spongiform Encephalopathy in Sheep by Use of Western Blotting and Immunohistochemical Methods

Lezmi, Stéphane, Martin, Stuart, Simon, Stéphanie, Comoy, Emmanuel, Bencsik, Anna, Deslys, Jean-Philippe, ...

Since the appearance of bovine spongiform encephalopathy (BSE) in cattle and its linkage with the human variant of Creutzfeldt-Jakob disease, the possible spread of this agent to sheep flocks has...

Molecular Analysis of the Protease-Resistant Prion Protein in Scrapie and Bovine Spongiform Encephalopathy Transmitted to Ovine Transgenic and Wild-Type Mice

Baron, Thierry, Crozet, Carole, Biacabe, Anne-Gaëlle, Philippe, Sandrine, Verchere, Jérémie, Bencsik, Anna, ...

The existence of different strains of infectious agents involved in scrapie, a transmissible spongiform encephalopathy (TSE) of sheep and goats, remains poorly explained. These strains can, however,...

Florid plaques in ovine PrP transgenic mice infected with an experimental ovine BSE

Crozet, Carole, Bencsik, Anna, Flamant, Frédéric, Lezmi, Stéphane, Samarut, Jacques, Baron, Thierry

The occurrence of the variant Creutzfeldt–Jakob disease (vCJD), related to bovine spongiform encephalopathy (BSE), raises the important question of the sources of human contamination. The...

Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein.

Thackray, Alana M, Madec, Jean-Yves, Wong, Edmond, Morgan-Warren, Robert, Brown, David R, Baron, Thierry, ...

Prion-related protein (PrP) is a glycosylphosphatidylinositol-linked cell-surface protein expressed by a wide variety of cells, including those of the nervous system and the immune system. Several...

A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes

Le Dur, Annick, Béringue, Vincent, Andréoletti, Olivier, Reine, Fabienne, Laï, Thanh Lan, Baron, Thierry, ...

Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can...

Distinct molecular phenotypes in bovine prion diseases

Biacabe, Anne-Gaëlle, Laplanche, Jean-Louis, Ryder, Stephen, Baron, Thierry

Bovine spongiform encephalopathy (BSE) in cattle, the most likely cause of variant Creutzfeldt–Jakob disease in humans, is thought to be caused by a unique infectious agent, with stable features,...

Isolation from Cattle of a Prion Strain Distinct from That Causing Bovine Spongiform Encephalopathy

Béringue, Vincent, Bencsik, Anna, Le Dur, Annick, Reine, Fabienne, Laï, Thanh Lan, Chenais, Nathalie, ...

To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain. This strain is characterised by a unique...

Molecular Discrimination of Atypical Bovine Spongiform Encephalopathy Strains from a Geographical Region Spanning a Wide Area in Europe† ▿

Jacobs, Jorg G., Langeveld, Jan P. M., Biacabe, Anne-Gaëlle, Acutis, Pier-Luigi, Polak, Miroslaw P., Gavier-Widen, Dolores, ...

Transmissible spongiform encephalopathy strains can be differentiated by their behavior in bioassays and by molecular analyses of the disease-associated prion protein (PrP) in a posttranslationally...

Molecular Behaviors of “CH1641-Like” Sheep Scrapie Isolates in Ovine Transgenic Mice (TgOvPrP4)▿

Baron, Thierry, Biacabe, Anne-Gaëlle

Molecular analyses of the protease-resistant prion protein (PrPres) from a few natural scrapie isolates showed by Western blotting some partial similarities with those observed in experimental ovine...

A C-Terminal Protease-Resistant Prion Fragment Distinguishes Ovine “CH1641-Like” Scrapie from Bovine Classical and L-Type BSE in Ovine Transgenic Mice

Baron, Thierry, Bencsik, Anna, Vulin, Johann, Biacabe, Anne-Gaëlle, Morignat, Eric, Verchere, Jérémy, ...

The protease-resistant prion protein (PrPres) of a few natural scrapie isolates identified in sheep, reminiscent of the experimental isolate CH1641 derived from a British natural scrapie case, showed...