A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4
Puca, Annibale A., Daly, Mark J., Brewster, Stephanie J., Matise, Tara C., Barrett, Jeffrey, Shea-Drinkwater, Maureen, ...
Substantial evidence supports the familial aggregation of exceptional longevity. The existence of rare families demonstrating clustering for this phenotype suggests that a genetic etiology may be an...
A Comprehensive View of Human Chromosome 1
White, Peter S., Sulman, Erik P., Porter, Christopher J., Matise, Tara C.
Comprehensive representations of human chromosomes combining diverse genomic data sets, localizing expressed sequences, and reflecting physical distance are essential for disease gene identification...
Widespread RNA Editing of Embedded Alu Elements in the Human Transcriptome
Kim, Dennis D.Y., Kim, Thomas T.Y., Walsh, Thomas, Kobayashi, Yoshifumi, Matise, Tara C., Buyske, Steven, ...
More than one million copies of the ∼300-bp Alu element are interspersed throughout the human genome, with up to 75% of all known genes having Alu insertions within their introns and/or UTRs....
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4
Puca, Annibale A., Daly, Mark J., Brewster, Stephanie J., Matise, Tara C., Barrett, Jeffrey, Shea-Drinkwater, Maureen, ...
Substantial evidence supports the familial aggregation of exceptional longevity. The existence of rare families demonstrating clustering for this phenotype suggests that a genetic etiology may be an...
A Comprehensive View of Human Chromosome 1
White, Peter S., Sulman, Erik P., Porter, Christopher J., Matise, Tara C.
Comprehensive representations of human chromosomes combining diverse genomic data sets, localizing expressed sequences, and reflecting physical distance are essential for disease gene identification...
Systematic Evaluation of Map Quality: Human Chromosome 22
Matise, Tara C., Porter, Christopher J., Buyske, Steven, Cuttichia, A. Jamie, Sulman, Erik P., White, Peter S.
Marker positions on nine genetic linkage, radiation hybrid, and integrated maps of human chromosome 22 were compared with their corresponding positions in the completed DNA sequence. The proportion...
The Map Problem: A Comparison of Genetic and Sequence-Based Physical Maps
DeWan, Andrew T., Parrado, Antonio R., Matise, Tara C., Leal, Suzanne M.
The genetic order of autosomal genome-scan markers from Marshfield panels 9 and 10 were compared with their physical order, on the basis of the assembled nonredundant human genome sequence from the...
Widespread RNA Editing of Embedded Alu Elements in the Human Transcriptome
Kim, Dennis D.Y., Kim, Thomas T.Y., Walsh, Thomas, Kobayashi, Yoshifumi, Matise, Tara C., Buyske, Steven, ...
More than one million copies of the ∼300-bp Alu element are interspersed throughout the human genome, with up to 75% of all known genes having Alu insertions within their introns and/or UTRs....
A 3.9-Centimorgan-Resolution Human Single-Nucleotide Polymorphism Linkage Map and Screening Set
Matise, Tara C., Sachidanandam, Ravi, Clark, Andrew G., Kruglyak, Leonid, Wijsman, Ellen, Kakol, Jerzy, ...
Recent advances in technologies for high-throughout single-nucleotide polymorphism (SNP)–based genotyping have improved efficiency and cost so that it is now becoming reasonable to consider the use...
Clark, Andrew G., Nielsen, Rasmus, Signorovitch, James, Matise, Tara C., Glanowski, Stephen, Heil, Jeremy, ...
The prospect of using linkage disequilibrium (LD) for fine-scale mapping in humans has attracted considerable attention, and, during the validation of a set of single-nucleotide polymorphisms (SNPs)...
Age-Related Macular Degeneration—a Genome Scan in Extended Families
Majewski, Jacek, Schultz, Dennis W., Weleber, Richard G., Schain, Mitchell B., Edwards, Albert O., Matise, Tara C., ...
We performed a genomewide scan and genetic linkage analysis, to identify loci associated with age-related macular degeneration (AMD). We collected 70 families, ranging from small nuclear families to...
A second-generation combined linkage–physical map of the human genome
Matise, Tara C., Chen, Fang, Chen, Wenwei, De La Vega, Francisco M., Hansen, Mark, He, Chunsheng, ...
We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical...