Suya Yang

Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb βs-globin yeast artificial chromosome: A mouse model of sickle cell anemia

Chang, Judy C., Lu, Ronghua, Lin, Chin, Xu, Shan-Mei, Kan, Yuet Wai, Porcu, Susanna, ...

Sickle cell anemia (SCA) and thalassemia are among the most common genetic diseases worldwide. Current approaches to the development of murine models of SCA involve the elimination of functional...

Sequences in the Aγ–δ intergenic region are not required for stage-specific regulation of the human β-globin gene locus

Gaensler, Karin M. L., Zhang, Zemin, Lin, Chin, Yang, Suya, Hardt, Karin, Flebbe-Rehwaldt, Linda

The human β-globin locus has been extensively studied as a model of tissue and developmental stage-specific gene expression. Structural mapping of naturally occurring mutations, including...

Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb βs-globin yeast artificial chromosome: A mouse model of sickle cell anemia

Chang, Judy C., Lu, Ronghua, Lin, Chin, Xu, Shan-Mei, Kan, Yuet Wai, Porcu, Susanna, ...

Sickle cell anemia (SCA) and thalassemia are among the most common genetic diseases worldwide. Current approaches to the development of murine models of SCA involve the elimination of functional...

Sequences in the Aγ–δ intergenic region are not required for stage-specific regulation of the human β-globin gene locus

Gaensler, Karin M. L., Zhang, Zemin, Lin, Chin, Yang, Suya, Hardt, Karin, Flebbe-Rehwaldt, Linda

The human β-globin locus has been extensively studied as a model of tissue and developmental stage-specific gene expression. Structural mapping of naturally occurring mutations, including...

Functional Roles for PECAM-1 (CD31) and VE-Cadherin (CD144) in Tube Assembly and Lumen Formation in Three-Dimensional Collagen Gels

Yang, Suya, Graham, Jennifer, Kahn, Jeanne W., Schwartz, Eric A., Gerritsen, Mary E.

Various in vitro models have been described that emulate one or more of the processes involved in angiogenesis in vivo. In the present study endothelial cells were cultured in three-dimensional type...

Hepatocyte Growth Factor Enhances Vascular Endothelial Growth Factor-Induced Angiogenesis in Vitro and in Vivo

Xin, Xiaohua, Yang, Suya, Ingle, Gladys, Zlot, Constance, Rangell, Linda, Kowalski, Joe, ...

Vascular endothelial growth factor (VEGF) is an important mediator of angiogenesis in both physiological and pathological processes. Hepatocyte growth factor (HGF) is a mesenchyme-derived mitogen...