Stefanie S. Jeffrey

New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients (2008)

Kohrt, Holbrook E, Olshen, Richard A, Bermas, Honnie R, Goodson, William H, Wood, Douglas J, Henry, Solomon, ...

Abstract Background Current practice is to perform a completion axillary lymph node dissection (ALND) for breast cancer patients with tumor-involved sentinel lymph nodes (SLNs), although fewer than...

RNA extraction from ten year old formalin-fixed paraffin-embedded breast cancer samples: a comparison of column purification and magnetic bead-based technologies (2007)

Ribeiro-Silva, Alfredo, Zhang, Haiyu, Jeffrey, Stefanie S

Abstract Background The development of protocols for RNA extraction from paraffin-embedded samples facilitates gene expression studies on archival samples with known clinical outcome. Older samples...

TP53mutation status and gene expression profiles are powerful prognostic markers of breast cancer (2007)

Langerød, Anita, Zhao, Hongjuan, Borgan, Ørnulf, Nesland, Jahn M, Bukholm, Ida RK, Ikdahl, Tone, ...

Abstract Introduction Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises to impact clinical care. The aim of this...

Correction: Discovery and validation of breast cancer subtypes (2007)

Kapp, Amy V, Jeffrey, Stefanie S, Langerød, Anita, Børresen-Dale, Anne-Lise, Han, Wonshik, Noh, Dong-Young, ...

Abstract Following the publication of our recent article (Kapp et al. , BMC Genomics 2006 , 7:231), we (the authors) regrettably found several errors in the published Table 5. This correction article...

Discovery and validation of breast cancer subtypes (2006)

Kapp, Amy V, Jeffrey, Stefanie S, Langerød, Anita, Børresen-Dale, Anne-Lise, Han, Wonshik, Noh, Dong-Young, ...

Abstract Background Previous studies demonstrated breast cancer tumor tissue samples could be classified into different subtypes based upon DNA microarray profiles. The most recent study presented...

A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue (2004)

Dairkee, Shanaz H, Ji, Youngran, Ben, Yong, Moore, Dan H, Meng, Zhenhang, Jeffrey, Stefanie S

Abstract Background To identify the spectrum of malignant attributes maintained outside the host environment, we have compared global gene expression in primary breast tumors and matched short-term...

The diagnosis and management of pre-invasive breast disease: Promise of new technologies in understanding pre-invasive breast lesions (2003)

Jeffrey, Stefanie S, Pollack, Jonathan R

Abstract Array-based comparative genomic hybridization, RNA expression profiling, and proteomic analyses are new molecular technologies used to study breast cancer. Invasive breast cancers were...

Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis (2002)

Zhao, Hongjuan, Hastie, Trevor, Whitfield, Michael L, Børresen-Dale, Anne-Lise, Jeffrey, Stefanie S

Abstract Background T7 based linear amplification of RNA is used to obtain sufficient antisense RNA for microarray expression profiling. We optimized and systematically evaluated the fidelity and...

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

Perou, Charles M., Jeffrey, Stefanie S., Van De Rijn, Matt, Rees, Christian A., Eisen, Michael B., Ross, Douglas T., ...

cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of...

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Sørlie, Therese, Perou, Charles M., Tibshirani, Robert, Aas, Turid, Geisler, Stephanie, Johnsen, Hilde, ...

The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A...

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

Pollack, Jonathan R., Sørlie, Therese, Perou, Charles M., Rees, Christian A., Jeffrey, Stefanie S., Lonning, Per E., ...

Genomic DNA copy number alterations are key genetic events in the development and progression of human cancers. Here we report a genome-wide microarray comparative genomic hybridization (array CGH)...

The diagnosis and management of pre-invasive breast disease: Promise of new technologies in understanding pre-invasive breast lesions

Jeffrey, Stefanie S, Pollack, Jonathan R

Array-based comparative genomic hybridization, RNA expression profiling, and proteomic analyses are new molecular technologies used to study breast cancer. Invasive breast cancers were originally...

Different Gene Expression Patterns in Invasive Lobular and Ductal Carcinomas of the Breast

Zhao, Hongjuan, Langerød, Anita, Ji, Youngran, Nowels, Kent W., Nesland, Jahn M., Tibshirani, Rob, ...

Invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) are the two major histological types of breast cancer worldwide. Whereas IDC incidence has remained stable, ILC is the most...

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

Perou, Charles M., Jeffrey, Stefanie S., Van De Rijn, Matt, Rees, Christian A., Eisen, Michael B., Ross, Douglas T., ...

cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of...

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Sørlie, Therese, Perou, Charles M., Tibshirani, Robert, Aas, Turid, Geisler, Stephanie, Johnsen, Hilde, ...

The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A...

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

Pollack, Jonathan R., Sørlie, Therese, Perou, Charles M., Rees, Christian A., Jeffrey, Stefanie S., Lonning, Per E., ...

Genomic DNA copy number alterations are key genetic events in the development and progression of human cancers. Here we report a genome-wide microarray comparative genomic hybridization (array CGH)...

The diagnosis and management of pre-invasive breast disease: Promise of new technologies in understanding pre-invasive breast lesions

Jeffrey, Stefanie S, Pollack, Jonathan R

Array-based comparative genomic hybridization, RNA expression profiling, and proteomic analyses are new molecular technologies used to study breast cancer. Invasive breast cancers were originally...

Different Gene Expression Patterns in Invasive Lobular and Ductal Carcinomas of the Breast

Zhao, Hongjuan, Langerød, Anita, Ji, Youngran, Nowels, Kent W., Nesland, Jahn M., Tibshirani, Rob, ...

Invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) are the two major histological types of breast cancer worldwide. Whereas IDC incidence has remained stable, ILC is the most...

Discovery and validation of breast cancer subtypes

Kapp, Amy V, Jeffrey, Stefanie S, Langerød, Anita, Børresen-Dale, Anne-Lise, Han, Wonshik, Noh, Dong-Young, ...

Following the publication of our recent article (Kapp et al., BMC Genomics 2006, 7:231), we (the authors) regrettably found several errors in the published Table 5. This correction article not only...