Stéphane Chédin

Is ribosome synthesis controlled by pol I transcription? (2008)

Chédin, Stéphane, Laferté, Arnaud, Hoang, Tran, Lafontaine, Denis L J, Riva, Michel, Carles, Christophe

Regulation of growth ultimately depends on the control of synthesis of new ribosomes. Ribosome biogenesis is thus a key element of cell biology, which is tightly regulated in response to...

The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination

Chédin, Stéphane, Riva, Michel, Schultz, Patrick, Sentenac, André, Carles, Christophe

Budding yeast RNA polymerase III (Pol III) contains a small, essential subunit, named C11, that is conserved in humans and shows a strong homology to TFIIS. A mutant Pol III, heterocomplemented with...

The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination

Chédin, Stéphane, Riva, Michel, Schultz, Patrick, Sentenac, André, Carles, Christophe

Budding yeast RNA polymerase III (Pol III) contains a small, essential subunit, named C11, that is conserved in humans and shows a strong homology to TFIIS. A mutant Pol III, heterocomplemented with...

The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components

Laferté, Arnaud, Favry, Emmanuel, Sentenac, André, Riva, Michel, Carles, Christophe, Chédin, Stéphane

Regulation of ribosome biogenesis is a key element of cell biology, not only because ribosomes are directly required for growth, but also because ribosome production monopolizes nearly 80% of the...

Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

Tribouillard-Tanvier, Déborah, Dos Reis, Suzana, Gug, Fabienne, Voisset, Cécile, Béringue, Vincent, Sabate, Raimon, ...