Hooper, Sean D., Boué, Stephanie, Krause, Roland, Jensen, Lars J., Mason, Christopher E., Ghanim, Murad, ...
Hooper, Sean D ., Boué, Stephanie, Krause, Roland, Jensen, Lars J ., Mason, Christopher E., Ghanim, Murad, ...
Time-series analysis of whole-genome expression data during Drosophila melanogaster development indicates that up to 86% of its genes change their relative transcript level during embryogenesis. By...
Systematic Association of Genes to Phenotypes by Genome and Literature Mining (2005)
Jan O. Korbel, Tobias Doerks, Lars J. Jensen, Carolina Perez-Iratxeta, Szymon Kaczanowski, Sean D. Hooper, ...
The combination of text mining and comparative genomics is shown to be a powerful approach to predicting phenotypes that are associated with particular genes in bacterial genomes.
Systematic Association of Genes to Phenotypes by Genome and Literature Mining (2005)
Jan O. Korbel, Tobias Doerks, Lars J. Jensen, Carolina Perez-Iratxeta, Szymon Kaczanowski, Sean D. Hooper, ...
One of the major challenges of functional genomics is to unravel the connection between genotype and phenotype. So far no global analysis has attempted to explore those connections in the light of...
Duplication is more common among laterally transferred genes than among indigenous genes (2003)
Abstract Background Recent developments in the understanding of paralogous evolution have prompted a focus not only on obviously advantageous genes, but also on genes that can be considered to have a...
Gradients in nucleotide and codon usage along Escherichia coli genes
Hooper, Sean D., Berg, Otto G.
The usage of codons and nucleotide combinations varies along genes and systematic variation causes gradients in usage. We have studied such gradients of nucleotides and nucleotide combinations and...
Duplication is more common among laterally transferred genes than among indigenous genes
Using both a compositional method and a gene-tree approach, a number of proposed laterally transferred genes have been identified and their nucleotide composition and frequency of duplication studied.
Von Mering, Christian, Jensen, Lars J., Snel, Berend, Hooper, Sean D., Krupp, Markus, Foglierini, Mathilde, ...
A full description of a protein's function requires knowledge of all partner proteins with which it specifically associates. From a functional perspective, ‘association’ can mean direct physical...
Systematic Association of Genes to Phenotypes by Genome and Literature Mining
Korbel, Jan O, Doerks, Tobias, Jensen, Lars J, Perez-Iratxeta, Carolina, Kaczanowski, Szymon, Hooper, Sean D, ...
One of the major challenges of functional genomics is to unravel the connection between genotype and phenotype. So far no global analysis has attempted to explore those connections in the light of...
Environments shape the nucleotide composition of genomes
Foerstner, Konrad U, Von Mering, Christian, Hooper, Sean D, Bork, Peer
To test the impact of environments on genome evolution, we analysed the relative abundance of the nucleotides guanine and cytosine (‘GC content') of large numbers of sequences from four distinct...
Gradients in nucleotide and codon usage along Escherichia coli genes
Hooper, Sean D., Berg, Otto G.
The usage of codons and nucleotide combinations varies along genes and systematic variation causes gradients in usage. We have studied such gradients of nucleotides and nucleotide combinations and...
Duplication is more common among laterally transferred genes than among indigenous genes
Using both a compositional method and a gene-tree approach, a number of proposed laterally transferred genes have been identified and their nucleotide composition and frequency of duplication studied.
Von Mering, Christian, Jensen, Lars J., Snel, Berend, Hooper, Sean D., Krupp, Markus, Foglierini, Mathilde, ...
A full description of a protein's function requires knowledge of all partner proteins with which it specifically associates. From a functional perspective, ‘association’ can mean direct physical...
Systematic Association of Genes to Phenotypes by Genome and Literature Mining
Korbel, Jan O, Doerks, Tobias, Jensen, Lars J, Perez-Iratxeta, Carolina, Kaczanowski, Szymon, Hooper, Sean D, ...
One of the major challenges of functional genomics is to unravel the connection between genotype and phenotype. So far no global analysis has attempted to explore those connections in the light of...
Environments shape the nucleotide composition of genomes
Foerstner, Konrad U, Von Mering, Christian, Hooper, Sean D, Bork, Peer
To test the impact of environments on genome evolution, we analysed the relative abundance of the nucleotides guanine and cytosine (‘GC content') of large numbers of sequences from four distinct...
Identification of tightly regulated groups of genes during Drosophila melanogaster embryogenesis
Hooper, Sean D, Boué, Stephanie, Krause, Roland, Jensen, Lars J, Mason, Christopher E, Ghanim, Murad, ...
Time-series analysis of whole-genome expression data during Drosophila melanogaster development indicates that up to 86% of its genes change their relative transcript level during embryogenesis. By...