Sara Olson

Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals

Kim, Sung-Kwon, Reed, Douglas S., Olson, Sara, Schnell, Matthias J., Rose, John K., Morton, Phillip A., ...

We compared peripheral and mucosal primary CD8 T cell responses to inflammatory and noninflammatory forms of antigen in a T cell-adoptive transfer system. Immunization with the soluble antigen,...

Enzyme interactions in heparan sulfate biosynthesis: Uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo

Pinhal, Maria A. S., Smith, Brian, Olson, Sara, Aikawa, Jun-ichi, Kimata, Koji, Esko, Jeffrey D.

The formation of heparan sulfate occurs within the lumen of the endoplasmic reticulum–Golgi complex–trans-Golgi network by the concerted action of several glycosyltransferases, an epimerase, and...

Characterization of U2AF6, a Splicing Factor Related to U2AF35

Shepard, Jeremiah, Reick, Martin, Olson, Sara, Graveley, Brenton R.

The essential splicing factor U2AF (U2 auxiliary factor) is a heterodimer composed of 65-kDa (U2AF65) and 35-kDa (U2AF35) subunits. U2AF35 has multiple functions in pre-mRNA splicing. First, U2AF35...

Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals

Kim, Sung-Kwon, Reed, Douglas S., Olson, Sara, Schnell, Matthias J., Rose, John K., Morton, Phillip A., ...

We compared peripheral and mucosal primary CD8 T cell responses to inflammatory and noninflammatory forms of antigen in a T cell-adoptive transfer system. Immunization with the soluble antigen,...

Enzyme interactions in heparan sulfate biosynthesis: Uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo

Pinhal, Maria A. S., Smith, Brian, Olson, Sara, Aikawa, Jun-ichi, Kimata, Koji, Esko, Jeffrey D.

The formation of heparan sulfate occurs within the lumen of the endoplasmic reticulum–Golgi complex–trans-Golgi network by the concerted action of several glycosyltransferases, an epimerase, and...

Characterization of U2AF6, a Splicing Factor Related to U2AF35

Shepard, Jeremiah, Reick, Martin, Olson, Sara, Graveley, Brenton R.

The essential splicing factor U2AF (U2 auxiliary factor) is a heterodimer composed of 65-kDa (U2AF65) and 35-kDa (U2AF35) subunits. U2AF35 has multiple functions in pre-mRNA splicing. First, U2AF35...

The Role of β7 Integrins in CD8 T Cell Trafficking During an Antiviral Immune Response

Lefrançois, Leo, Parker, Christina M., Olson, Sara, Muller, Werner, Wagner, Norbert, Puddington, Lynn

The requirement of β7 integrins for lymphocyte migration was examined during an ongoing immune response in vivo. Transgenic mice (OT-I) expressing an ovalbumin-specific major histocompatibility...

A Critical Role for Cd40–Cd40 Ligand Interactions in Amplification of the Mucosal Cd8 T Cell Response

Lefrançois, Leo, Olson, Sara, Masopust, David

The role of CD40 ligand (CD40L) in CD8 T cell activation was assessed by tracking antigen-specific T cells in vivo using both adoptive transfer of T cell receptor transgenic T cells and major...

Enterocyte Expression of Interleukin 7 Induces Development of γδ T Cells and Peyer's Patches

Laky, Karen, Lefrançois, Leo, Lingenheld, Elizabeth G., Ishikawa, Hiromichi, Lewis, Julia M., Olson, Sara, ...

The intestinal mucosa is suggested to support extrathymic T cell development, particularly for T cell receptor (TCR)-γδ intraepithelial lymphocytes (IELs). TCR-γδ cell development requires...