Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis (2006)
Neasta, Jérémie, Uttenweiler-Joseph, Sandrine, Chaoui, Karima, Monsarrat, Bernard, Meunier, Jean-Claude, Moulédous, Lionel
Abstract Background Opiate addiction reflects plastic changes that endurably alter synaptic transmission within relevant neuronal circuits. The biochemical mechanisms of these adaptations remain...
The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms (2004)
Carsten Schnatwinkel, Savvas Christoforidis, Margaret R. Lindsay, Sandrine Uttenweiler-Joseph, Matthias Wilm, Robert G. Parton, ...
Rabankyrin-5, which is activated by the small GTPase Rab5, coordinates two disparate methods that cells use to take in solids and fluids, playing a key role in both endosome fusion and...
The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms (2004)
Carsten Schnatwinkel, Savvas Christoforidis, Margaret R. Lindsay, Sandrine Uttenweiler-Joseph, Matthias Wilm, Robert G. Parton, ...
The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5...
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. (2004)
Miaczynska, Marta, Christoforidis, Savvas, Giner, Angelika, Shevchenko, Anna, Uttenweiler-Joseph, Sandrine, Habermann, Bianca, ...
Signals generated in response to extracellular stimuli at the plasma membrane are transmitted through cytoplasmic transduction cascades to the nucleus. We report the identification of a pathway...
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. (2004)
Schnatwinkel, Carsten, Christoforidis, Savvas, Lindsay, Margaret R, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Parton, Robert G, ...
The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5...
The Rab5 effector rabankyrin-5 regulates and coordinates different endocytic mechanisms (2004)
Schnatwinkel, Carsten, Christoforidis, Savvas, Lindsay, Margaret R., Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Parton, Robert G., ...
The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5...
Uttenweiler-Joseph, Sandrine, Moniatte, Marc, Lagueux, Marie, Van Dorsselaer, Alain, Hoffmann, Jules A., Bulet, Philippe
We have developed an approach based on a differential mass spectrometric analysis to detect molecules induced during the immune response of Drosophila, regardless of their biological activities. For...
Schmidt, Gudula, Goehring, Udo-Michael, Schirmer, Joerg, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Lohmann, Mark, ...
Bordetella dermonecrotic toxin (DNT) catalyzes the transglutamination of glutamine-63/61 of Rho GTPases, thereby constitutively activating Rho proteins. Here we identified second substrates for...
The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms
Schnatwinkel, Carsten, Christoforidis, Savvas, Lindsay, Margaret R, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Parton, Robert G, ...
The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5...
Uttenweiler-Joseph, Sandrine, Moniatte, Marc, Lagueux, Marie, Van Dorsselaer, Alain, Hoffmann, Jules A., Bulet, Philippe
We have developed an approach based on a differential mass spectrometric analysis to detect molecules induced during the immune response of Drosophila, regardless of their biological activities. For...
Schmidt, Gudula, Goehring, Udo-Michael, Schirmer, Joerg, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Lohmann, Mark, ...
Bordetella dermonecrotic toxin (DNT) catalyzes the transglutamination of glutamine-63/61 of Rho GTPases, thereby constitutively activating Rho proteins. Here we identified second substrates for...
The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms
Schnatwinkel, Carsten, Christoforidis, Savvas, Lindsay, Margaret R, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Parton, Robert G, ...
The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5...
Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis
Neasta, Jérémie, Uttenweiler-Joseph, Sandrine, Chaoui, Karima, Monsarrat, Bernard, Meunier, Jean-Claude, Moulédous, Lionel
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
Shin, Hye-Won, Hayashi, Mitsuko, Christoforidis, Savvas, Lacas-Gervais, Sandra, Hoepfner, Sebastian, Wenk, Markus R., ...
Generation and turnover of phosphoinositides (PIs) must be coordinated in a spatial- and temporal-restricted manner. The small GTPase Rab5 interacts with two PI 3-kinases, Vps34 and PI3Kβ,...
Nielsen, Erik, Christoforidis, Savvas, Uttenweiler-Joseph, Sandrine, Miaczynska, Marta, Dewitte, Frederique, Wilm, Matthias, ...
Rab5 regulates endocytic membrane traffic by specifically recruiting cytosolic effector proteins to their site of action on early endosomal membranes. We have characterized a new Rab5 effector...