Lin, Jian Sheng, Dauvilliers, Yves, Arnulf, Isabelle, Bastuji, Hélène, Anaclet, Christelle, Parmentier, Régis, ...
Narcolepsy is characterized by excessive daytime sleepiness (EDS), cataplexy, direct onsets of rapid eye movement (REM) sleep from wakefulness (DREMs) and deficiency of orexins, neuropeptides that...
Lin, Jian Sheng, Dauvilliers, Yves, Arnulf, Isabelle, Bastuji, Hélène, Anaclet, Christelle, Parmentier, Régis, ...
Narcolepsy is characterized by excessive daytime sleepiness (EDS), cataplexy, direct onsets of rapid eye movement (REM) sleep from wakefulness (DREMs) and deficiency of orexins, neuropeptides that...
The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders. (2007)
Parmentier, Régis, Anaclet, Christelle, Guhennec, Christian, Brousseau, Emmanuel, Bricout, Denis, Giboulot, Thierry, ...
Brain histaminergic neurons play a prominent role in arousal and maintenance of wakefulness (W). H(3)-receptors control the activity of histaminergic neurons through presynaptic autoinhibition. The...
Ligneau, Xavier, Landais, Laurent, Perrin, David, Piriou, Johanne, Uguen, Marilyne, Denis, Emmanuel, ...
BF2.649, a high affinity and selective non-imidazole histamine H(3)-receptor antagonist/inverse agonist, was found to easily enter the brain after oral administration to mice: it displayed a ratio of...
The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders. (2007)
Parmentier, Régis, Anaclet, Christelle, Guhennec, Christian, Brousseau, Emmanuel, Bricout, Denis, Giboulot, Thierry, ...
Brain histaminergic neurons play a prominent role in arousal and maintenance of wakefulness (W). H(3)-receptors control the activity of histaminergic neurons through presynaptic autoinhibition. The...
Ligneau, Xavier, Landais, Laurent, Perrin, David, Piriou, Johanne, Uguen, Marilyne, Denis, Emmanuel, ...
BF2.649, a high affinity and selective non-imidazole histamine H(3)-receptor antagonist/inverse agonist, was found to easily enter the brain after oral administration to mice: it displayed a ratio of...
Protean agonism at histamine H3 receptors in vitro and in vivo
Gbahou, Florence, Rouleau, Agnès, Morisset, Séverine, Parmentier, Régis, Crochet, Sylvain, Lin, Jian-Sheng, ...
G protein-coupled receptors (GPCRs) are allosteric proteins that adopt inactive (R) and active (R*) conformations in equilibrium. R* is promoted by agonists or occurs spontaneously, leading to...
Protean agonism at histamine H3 receptors in vitro and in vivo
Gbahou, Florence, Rouleau, Agnès, Morisset, Séverine, Parmentier, Régis, Crochet, Sylvain, Lin, Jian-Sheng, ...
G protein-coupled receptors (GPCRs) are allosteric proteins that adopt inactive (R) and active (R*) conformations in equilibrium. R* is promoted by agonists or occurs spontaneously, leading to...