InteroPORC: an automated tool to predict highly conserved protein interaction networks (2008)
Michaut, Magali, Kerrien, Samuel, Montecchi-Palazzi, Luisa, Cassier-Chauvat, Corinne, Chauvat, Franck, Aude, Jean-Christophe, ...
No abstract available.
Houot, Laetitia, Floutier, Martin, Marteyn, Benoit, Michaut, Magali, Picciocchi, Antoine, Legrain, Pierre, ...
Abstract Background Cadmium is a persistent pollutant that threatens most biological organisms, including cyanobacteria that support a large part of the biosphere. Using a multifaceted approach, we...
Sousa, Sandra, Cabanes, Didier, Archambaud, Cristel, Colland, Frédéric, Lemichez, Emmanuel, Popoff, Michel, ...
E-cadherin mediates the formation of adherens junctions between epithelial cells. It serves as a receptor for Listeria monocytogenes, a bacterial pathogen that enters epithelial cells. The L....
Septicémies au cours de l'évolution des blessures de guerre. (1918)
Paris theses 1917-18. No. 81.
Parallel analysis of genetic selections using whole genome oligonucleotide arrays
Cho, Raymond J., Fromont-Racine, Micheline, Wodicka, Lisa, Feierbach, Becket, Stearns, Timothy, Legrain, Pierre, ...
Thousands of genes have recently been sequenced in organisms ranging from Escherichia coli to human. For the majority of these genes, however, available sequence does not define a biological role....
Jensen, Torben Heick, Neville, Megan, Rain, Jean Christophe, McCarthy, Terri, Legrain, Pierre, Rosbash, Michael
Nuclear export of proteins containing leucine-rich nuclear export signals (NESs) is mediated by the NES receptor CRM1/Crm1p. We have carried out a yeast two-hybrid screen with Crm1p as a bait. The...
Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms
Siomi, Mikiko C., Fromont, Micheline, Rain, Jean-Christophe, Wan, Lili, Wang, Fan, Legrain, Pierre, ...
Human transportin1 (hTRN1) is the nuclear import receptor for a group of pre-mRNA/mRNA-binding proteins (heterogeneous nuclear ribonucleoproteins [hnRNP]) represented by hnRNP A1, which shuttle...
Boëda, Batiste, El-Amraoui, Aziz, Bahloul, Amel, Goodyear, Richard, Daviet, Laurent, Blanchard, Stéphane, ...
Deaf-blindness in three distinct genetic forms of Usher type I syndrome (USH1) is caused by defects in myosin VIIa, harmonin and cadherin 23. Despite being critical for hearing, the functions of...
Antiviral Drug Discovery Strategy Using Combinatorial Libraries of Structurally Constrained Peptides
Real, Eléonore, Rain, Jean-Christophe, Battaglia, Véronique, Jallet, Corinne, Perrin, Pierre, Tordo, Noël, ...
We have developed a new strategy for antiviral peptide discovery by using lyssaviruses (rabies virus and rabies-related viruses) as models. Based on the mimicry of natural bioactive peptides, two...
Functional Proteomics Mapping of a Human Signaling Pathway
Colland, Frédéric, Jacq, Xavier, Trouplin, Virginie, Mougin, Christelle, Groizeleau, Caroline, Hamburger, Alexandre, ...
Access to the human genome facilitates extensive functional proteomics studies. Here, we present an integrated approach combining large-scale protein interaction mapping, exploration of the...
Kim, Dong Wook, Lenzen, Gerlinde, Page, Anne-Laure, Legrain, Pierre, Sansonetti, Philippe J., Parsot, Claude
Bacteria of Shigella spp. are responsible for shigellosis in humans. They use a type III secretion system to inject effector proteins into host cells and induce their entry into epithelial cells or...
Protein interaction mapping: A Drosophila case study
Formstecher, Etienne, Aresta, Sandra, Collura, Vincent, Hamburger, Alexandre, Meil, Alain, Trehin, Alexandra, ...
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based...
Parallel analysis of genetic selections using whole genome oligonucleotide arrays
Cho, Raymond J., Fromont-Racine, Micheline, Wodicka, Lisa, Feierbach, Becket, Stearns, Timothy, Legrain, Pierre, ...
Thousands of genes have recently been sequenced in organisms ranging from Escherichia coli to human. For the majority of these genes, however, available sequence does not define a biological role....
Jensen, Torben Heick, Neville, Megan, Rain, Jean Christophe, McCarthy, Terri, Legrain, Pierre, Rosbash, Michael
Nuclear export of proteins containing leucine-rich nuclear export signals (NESs) is mediated by the NES receptor CRM1/Crm1p. We have carried out a yeast two-hybrid screen with Crm1p as a bait. The...
Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms
Siomi, Mikiko C., Fromont, Micheline, Rain, Jean-Christophe, Wan, Lili, Wang, Fan, Legrain, Pierre, ...
Human transportin1 (hTRN1) is the nuclear import receptor for a group of pre-mRNA/mRNA-binding proteins (heterogeneous nuclear ribonucleoproteins [hnRNP]) represented by hnRNP A1, which shuttle...
Boëda, Batiste, El-Amraoui, Aziz, Bahloul, Amel, Goodyear, Richard, Daviet, Laurent, Blanchard, Stéphane, ...
Deaf-blindness in three distinct genetic forms of Usher type I syndrome (USH1) is caused by defects in myosin VIIa, harmonin and cadherin 23. Despite being critical for hearing, the functions of...
Antiviral Drug Discovery Strategy Using Combinatorial Libraries of Structurally Constrained Peptides
Real, Eléonore, Rain, Jean-Christophe, Battaglia, Véronique, Jallet, Corinne, Perrin, Pierre, Tordo, Noël, ...
We have developed a new strategy for antiviral peptide discovery by using lyssaviruses (rabies virus and rabies-related viruses) as models. Based on the mimicry of natural bioactive peptides, two...
Functional Proteomics Mapping of a Human Signaling Pathway
Colland, Frédéric, Jacq, Xavier, Trouplin, Virginie, Mougin, Christelle, Groizeleau, Caroline, Hamburger, Alexandre, ...
Access to the human genome facilitates extensive functional proteomics studies. Here, we present an integrated approach combining large-scale protein interaction mapping, exploration of the...
Protein interaction mapping: A Drosophila case study
Formstecher, Etienne, Aresta, Sandra, Collura, Vincent, Hamburger, Alexandre, Meil, Alain, Trehin, Alexandra, ...
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based...
Kim, Dong Wook, Lenzen, Gerlinde, Page, Anne-Laure, Legrain, Pierre, Sansonetti, Philippe J., Parsot, Claude
Bacteria of Shigella spp. are responsible for shigellosis in humans. They use a type III secretion system to inject effector proteins into host cells and induce their entry into epithelial cells or...
Houot, Laetitia, Floutier, Martin, Marteyn, Benoit, Michaut, Magali, Picciocchi, Antoine, Legrain, Pierre, ...
Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins
Fromont-Racine, Micheline, Mayes, Andrew E., Brunet-Simon, Adeline, Rain, Jean-Christophe, Colley, Alan, Dix, Ian, ...
A set of seven structurally related Sm proteins forms the core of the snRNP particles containing the spliceosomal U1, U2, U4 and U5 snRNAs. A search of the genomic sequence of Saccharomyces...