Phuong Le

Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase

Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., ...

Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of...

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, ...

HGK (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) is a member of the human STE20/mitogen-activated protein kinase kinase kinase kinase family of serine/threonine kinases and...

Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase

Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., ...

Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of...

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, ...

HGK (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) is a member of the human STE20/mitogen-activated protein kinase kinase kinase kinase family of serine/threonine kinases and...

Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block

Dravid, Shashank M, Erreger, Kevin, Yuan, Hongjie, Nicholson, Katherine, Le, Phuong, Lyuboslavsky, Polina, ...

We have compared the potencies of structurally distinct channel blockers at recombinant NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D receptors. The IC50 values varied with stereochemistry and subunit...