c-Myc Functionally Cooperates with Bax To Induce Apoptosis
Juin, Philippe, Hunt, Abigail, Littlewood, Trevor, Griffiths, Beatrice, Brown Swigart, Lamorna, Korsmeyer, Stanley, ...
c-Myc promotes apoptosis by destabilizing mitochondrial integrity, leading to the release of proapoptotic effectors including holocytochrome c. Candidate mediators of c-Myc in this process are the...
Nonredundant Role of Bax and Bak in Bid-Mediated Apoptosis
Cartron, Pierre-François, Juin, Philippe, Oliver, Lisa, Martin, Stéphane, Meflah, Khaled, Vallette, François M.
Animal models suggest that Bax and Bak play an essential role in the implementation of apoptosis and as a result can hinder tumorigenesis. We analyzed the expression of these proteins in 50 human...
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
Juin, Philippe, Hueber, Anne-Odile, Littlewood, Trevor, Evan, Gerard
Expression of c-Myc sensitizes cells to a wide range of pro-apoptotic stimuli. We here show that this pro-apoptotic effect is mediated through release of mitochondrial holocytochrome c into the...
c-Myc Functionally Cooperates with Bax To Induce Apoptosis
Juin, Philippe, Hunt, Abigail, Littlewood, Trevor, Griffiths, Beatrice, Brown Swigart, Lamorna, Korsmeyer, Stanley, ...
c-Myc promotes apoptosis by destabilizing mitochondrial integrity, leading to the release of proapoptotic effectors including holocytochrome c. Candidate mediators of c-Myc in this process are the...
Nonredundant Role of Bax and Bak in Bid-Mediated Apoptosis
Cartron, Pierre-François, Juin, Philippe, Oliver, Lisa, Martin, Stéphane, Meflah, Khaled, Vallette, François M.
Animal models suggest that Bax and Bak play an essential role in the implementation of apoptosis and as a result can hinder tumorigenesis. We analyzed the expression of these proteins in 50 human...
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
Juin, Philippe, Hueber, Anne-Odile, Littlewood, Trevor, Evan, Gerard
Expression of c-Myc sensitizes cells to a wide range of pro-apoptotic stimuli. We here show that this pro-apoptotic effect is mediated through release of mitochondrial holocytochrome c into the...
Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1
Maiuri, M Chiara, Le Toumelin, Gaëtane, Criollo, Alfredo, Rain, Jean-Christophe, Gautier, Fabien, Juin, Philippe, ...
The anti-apoptotic proteins Bcl-2 and Bcl-XL bind and inhibit Beclin-1, an essential mediator of autophagy. Here, we demonstrate that this interaction involves a BH3 domain within Beclin-1 (residues...