A serpin mutant links Toll activation to melanization in the host defence of Drosophila
Ligoxygakis, Petros, Pelte, Nadège, Ji, Chuanyi, Leclerc, Vincent, Duvic, Bernard, Belvin, Marcia, ...
A prominent response during the Drosophila host defence is the induction of proteolytic cascades, some of which lead to localized melanization of pathogen surfaces, while others activate one of the...
Ligoxygakis, Petros, Bulet, Philippe, Reichhart, Jean-Marc
Essential aspects of innate immune responses to microbial infections appear to be conserved between insects and mammals. In particular, in both groups, transmembrane receptors of the Toll superfamily...
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway
Filipe, Sergio R, Tomasz, Alexander, Ligoxygakis, Petros
The Drosophila immune system is able to discriminate between classes of bacteria. Detection of Gram-positive bacteria involves a complex of two pattern recognition receptors: peptidoglycan...
A serpin mutant links Toll activation to melanization in the host defence of Drosophila
Ligoxygakis, Petros, Pelte, Nadège, Ji, Chuanyi, Leclerc, Vincent, Duvic, Bernard, Belvin, Marcia, ...
A prominent response during the Drosophila host defence is the induction of proteolytic cascades, some of which lead to localized melanization of pathogen surfaces, while others activate one of the...
Ligoxygakis, Petros, Bulet, Philippe, Reichhart, Jean-Marc
Essential aspects of innate immune responses to microbial infections appear to be conserved between insects and mammals. In particular, in both groups, transmembrane receptors of the Toll superfamily...
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway
Filipe, Sergio R, Tomasz, Alexander, Ligoxygakis, Petros
The Drosophila immune system is able to discriminate between classes of bacteria. Detection of Gram-positive bacteria involves a complex of two pattern recognition receptors: peptidoglycan...
Prophenoloxidase activation is not required for survival to microbial infections in Drosophila
Leclerc, Vincent, Pelte, Nadège, Chamy, Laure El, Martinelli, Cosimo, Ligoxygakis, Petros, Hoffmann, Jules A, ...
The antimicrobial defence of Drosophila relies on cellular and humoral processes, of which the inducible synthesis of antimicrobial peptides has attracted interest in recent years. Another potential...
Wang, Lihui, Weber, Alexander N R, Atilano, Magda L, Filipe, Sergio R, Gay, Nicholas J, Ligoxygakis, Petros
Genetic evidence indicates that Drosophila defense against Gram-positive bacteria is mediated by two putative pattern recognition receptors acting upstream of Toll, namely Gram-negative binding...