SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets (2007)
Lai, Carmen, Horlings, Hugo M, Van De Vijver, Marc J, Van Beers, Eric H, Nederlof, Petra M, Wessels, Lodewyk FA, ...
Abstract Background Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, leading to...
Automated array-CGH optimized for archival formalin-fixed, paraffin-embedded tumor material (2007)
Joosse, Simon A, Van Beers, Erik H, Nederlof, Petra M
Abstract Background Array Comparative Genomic Hybridization (aCGH) is a rapidly evolving technology that still lacks complete standardization. Yet, it is of great importance to obtain robust and...
Array-CGH and breast cancer (2006)
Van Beers, Erik H, Nederlof, Petra M
Abstract The introduction of comparative genomic hybridization (CGH) in 1992 opened new avenues in genomic investigation; in particular, it advanced analysis of solid tumours, including breast...
Van Beers, Erik H, Nederlof, Petra M
The introduction of comparative genomic hybridization (CGH) in 1992 opened new avenues in genomic investigation; in particular, it advanced analysis of solid tumours, including breast cancer, because...
Van Beers, Erik H, Nederlof, Petra M
The introduction of comparative genomic hybridization (CGH) in 1992 opened new avenues in genomic investigation; in particular, it advanced analysis of solid tumours, including breast cancer, because...
Analysis of PALB2/FANCN-associated breast cancer families
Tischkowitz, Marc, Xia, Bing, Sabbaghian, Nelly, Reis-Filho, Jorge S., Hamel, Nancy, Li, Guilan, ...
No more than ≈30% of hereditary breast cancer has been accounted for by mutations in known genes. Most of these genes, such as BRCA1, BRCA2, TP53, CHEK2, ATM, and FANCJ/BRIP1, function in DNA...