Peter R. Hoffmann

West Nile Virus Surveillance: A Simple Method for Verifying the Integrity of RNA in Mosquito (Diptera: Culicidae) Pools (2004)

Peter R. Hoffmann, Robert J. Woodrow, Precilia S. Calimlim, Rebecca Sciulli, Paul V. Effler, Vernon Miyamoto, ...

In a West Nile virus (WNV)-free ecosystem, it is essential to verify the integrity of RNA before concluding that RNA extracted from mosquito specimens is negative for WNV gene sequences. The primary...

Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis

Vandivier, R. William, Fadok, Valerie A., Hoffmann, Peter R., Bratton, Donna L., Penvari, Churee, Brown, Kevin K., ...

Cystic fibrosis is characterized by an early and sustained influx of inflammatory cells into the airways and by release of proteases. Resolution of inflammation is normally associated with the...

Nuclear Assembly of UGA Decoding Complexes on Selenoprotein mRNAs: a Mechanism for Eluding Nonsense-Mediated Decay?

De Jesus, Lucia A., Hoffmann, Peter R., Michaud, Tanya, Forry, Erin P., Small-Howard, Andrea, Stillwell, Robert J., ...

Recoding of UGA from a stop codon to selenocysteine poses a dilemma for the protein translation machinery. In eukaryotes, two factors that are crucial to this recoding process are the mRNA binding...

Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis

Vandivier, R. William, Fadok, Valerie A., Hoffmann, Peter R., Bratton, Donna L., Penvari, Churee, Brown, Kevin K., ...

Cystic fibrosis is characterized by an early and sustained influx of inflammatory cells into the airways and by release of proteases. Resolution of inflammation is normally associated with the...

Nuclear Assembly of UGA Decoding Complexes on Selenoprotein mRNAs: a Mechanism for Eluding Nonsense-Mediated Decay?

De Jesus, Lucia A., Hoffmann, Peter R., Michaud, Tanya, Forry, Erin P., Small-Howard, Andrea, Stillwell, Robert J., ...

Recoding of UGA from a stop codon to selenocysteine poses a dilemma for the protein translation machinery. In eukaryotes, two factors that are crucial to this recoding process are the mRNA binding...

The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply

Hoffmann, Peter R., Höge, Simone C., Li, Ping-An, Hoffmann, Fukun W., Hashimoto, Ann C., Berry, Marla J.

Selenoprotein P (Sel P) is a selenium-rich glycoprotein believed to play a key role in selenium (Se) transport throughout the body. Development of a Sel P knockout mouse model has supported this...

C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

Ogden, Carol Anne, DeCathelineau, Aimee, Hoffmann, Peter R., Bratton, Donna, Ghebrehiwet, Berhane, Fadok, Valerie A., ...

Removal of apoptotic cells is essential for maintenance of tissue homeostasis, organogenesis, remodeling, development, and maintenance of the immune system, protection against neoplasia, and...

Phosphatidylserine (PS) induces PS receptor–mediated macropinocytosis and promotes clearance of apoptotic cells

Hoffmann, Peter R., DeCathelineau, Aimee M., Ogden, Carol Anne, Leverrier, Yann, Bratton, Donna L., Daleke, David L., ...

Efficient phagocytosis of apoptotic cells is important for normal tissue development, homeostasis, and the resolution of inflammation. Although many receptors have been implicated in the clearance of...