Peter J. Dailey

9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) Therapy Prolongs Survival of Infant Macaques Inoculated with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

Cherrington, Julie M., Marthas, Marta L., Lamy, Patrick D., Dailey, Peter J., Canfield, Don R., ...

Simian immunodeficiency virus (SIV) infection of newborn rhesus macaques is a useful animal model of human immunodeficiency virus infection for the study of the emergence and clinical implications of...

Rapid Clearance of Simian Immunodeficiency Virus Particles from Plasma of Rhesus Macaques

Zhang, Linqi, Dailey, Peter J., He, Tian, Gettie, Agegnehu, Bonhoeffer, Sebastian, Perelson, Alan S., ...

Perturbation of the equilibrium between human immunodeficiency virus type 1 (HIV-1) and the infected host by administering antiretroviral agents has revealed the rapid turnover of both viral...

Early Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine Treatment Favorably Alters the Subsequent Disease Course in Simian Immunodeficiency Virus-Infected Newborn Rhesus Macaques

Dailey, Peter J., Tarara, Ross P., Canfield, Don R., Aguirre, Nancy L., Cherrington, Julie M., ...

Simian immunodeficiency virus (SIV) infection of newborn macaques is a useful animal model of human pediatric AIDS to study disease pathogenesis and to develop intervention strategies aimed at...

In Vivo Replication Capacity Rather Than In Vitro Macrophage Tropism Predicts Efficiency of Vaginal Transmission of Simian Immunodeficiency Virus or Simian/Human Immunodeficiency Virus in Rhesus Macaques

Miller, Christopher J., Marthas, Marta, Greenier, Jennifer, Lu, Ding, Dailey, Peter J., Lu, Yichen

We used the rhesus macaque model of heterosexual human immunodeficiency virus (HIV) transmission to test the hypothesis that in vitro measures of macrophage tropism predict the ability of a primate...

Temporal Analyses of Virus Replication, Immune Responses, and Efficacy in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine

Connor, Ruth I., Montefiori, David C., Binley, James M., Moore, John P., Bonhoeffer, Sebastian, Gettie, Agegnehu, ...

Despite evidence that live, attenuated simian immunodeficiency virus (SIV) vaccines can elicit potent protection against pathogenic SIV infection, detailed information on the replication kinetics of...

In Vivo Replication Capacity Rather Than In Vitro Macrophage Tropism Predicts Efficiency of Vaginal Transmission of Simian Immunodeficiency Virus or Simian/Human Immunodeficiency Virus in Rhesus Macaques

Miller, Christopher J., Marthas, Marta, Greenier, Jennifer, Lu, Ding, Dailey, Peter J., Lu, Yichen

Prophylactic and Therapeutic Benefits of Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine (PMPA) Administration to Newborn Macaques following Oral Inoculation with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

Miller, Michael D., Marthas, Marta L., Margot, Nicolas A., Dailey, Peter J., Canfield, Don R., ...

Simian immunodeficiency virus (SIV) infection of newborn macaques is a useful animal model of human pediatric AIDS to study pathogenesis and to develop intervention strategies aimed at preventing...

Simian Immunodeficiency Virus Disease Course Is Predicted by the Extent of Virus Replication during Primary Infection

Staprans, Silvija I., Dailey, Peter J., Rosenthal, Ann, Horton, Chris, Grant, Robert M., Lerche, Nicholas, ...

To elucidate the relationship between early viral infection events and immunodeficiency virus disease progression, quantitative-competitive and branched-DNA methods of simian immunodeficiency virus...

Route of Simian Immunodeficiency Virus Inoculation Determines the Complexity but Not the Identity of Viral Variant Populations That Infect Rhesus Macaques

Greenier, Jennifer L., Miller, Christopher J., Lu, Ding, Dailey, Peter J., Lü, Fabien X., Kunstman, Kevin J., ...

A better understanding of the host and viral factors associated with human immunodeficiency virus (HIV) transmission is essential to developing effective strategies to curb the global HIV epidemic....

The Liver Is a Major Organ for Clearing Simian Immunodeficiency Virus in Rhesus Monkeys

Zhang, Linqi, Dailey, Peter J., Gettie, Agegnehu, Blanchard, Jim, Ho, David D.

Infection with human or simian immunodeficiency virus (SIV) is characterized by the rapid turnover of both viral particles and productively infected cells. It has recently been reported that the...

Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus–infected monkeys

Fox, Howard S., Weed, Michael R., Huitron-Resendiz, Salvador, Baig, Jamal, Horn, Thomas F.W., Dailey, Peter J., ...

Simian immunodeficiency virus (SIV) infection of rhesus monkeys provides an excellent model of the central nervous system (CNS) consequences of HIV infection. To discern the relationship between...

9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) Therapy Prolongs Survival of Infant Macaques Inoculated with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

Cherrington, Julie M., Marthas, Marta L., Lamy, Patrick D., Dailey, Peter J., Canfield, Don R., ...

Simian immunodeficiency virus (SIV) infection of newborn rhesus macaques is a useful animal model of human immunodeficiency virus infection for the study of the emergence and clinical implications of...

Rapid Clearance of Simian Immunodeficiency Virus Particles from Plasma of Rhesus Macaques

Zhang, Linqi, Dailey, Peter J., He, Tian, Gettie, Agegnehu, Bonhoeffer, Sebastian, Perelson, Alan S., ...

Perturbation of the equilibrium between human immunodeficiency virus type 1 (HIV-1) and the infected host by administering antiretroviral agents has revealed the rapid turnover of both viral...

Early Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine Treatment Favorably Alters the Subsequent Disease Course in Simian Immunodeficiency Virus-Infected Newborn Rhesus Macaques

Dailey, Peter J., Tarara, Ross P., Canfield, Don R., Aguirre, Nancy L., Cherrington, Julie M., ...

Simian immunodeficiency virus (SIV) infection of newborn macaques is a useful animal model of human pediatric AIDS to study disease pathogenesis and to develop intervention strategies aimed at...

In Vivo Replication Capacity Rather Than In Vitro Macrophage Tropism Predicts Efficiency of Vaginal Transmission of Simian Immunodeficiency Virus or Simian/Human Immunodeficiency Virus in Rhesus Macaques

Miller, Christopher J., Marthas, Marta, Greenier, Jennifer, Lu, Ding, Dailey, Peter J., Lu, Yichen

We used the rhesus macaque model of heterosexual human immunodeficiency virus (HIV) transmission to test the hypothesis that in vitro measures of macrophage tropism predict the ability of a primate...

Temporal Analyses of Virus Replication, Immune Responses, and Efficacy in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine

Connor, Ruth I., Montefiori, David C., Binley, James M., Moore, John P., Bonhoeffer, Sebastian, Gettie, Agegnehu, ...

Despite evidence that live, attenuated simian immunodeficiency virus (SIV) vaccines can elicit potent protection against pathogenic SIV infection, detailed information on the replication kinetics of...

In Vivo Replication Capacity Rather Than In Vitro Macrophage Tropism Predicts Efficiency of Vaginal Transmission of Simian Immunodeficiency Virus or Simian/Human Immunodeficiency Virus in Rhesus Macaques

Miller, Christopher J., Marthas, Marta, Greenier, Jennifer, Lu, Ding, Dailey, Peter J., Lu, Yichen

Prophylactic and Therapeutic Benefits of Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine (PMPA) Administration to Newborn Macaques following Oral Inoculation with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

Miller, Michael D., Marthas, Marta L., Margot, Nicolas A., Dailey, Peter J., Canfield, Don R., ...

Simian immunodeficiency virus (SIV) infection of newborn macaques is a useful animal model of human pediatric AIDS to study pathogenesis and to develop intervention strategies aimed at preventing...

Simian Immunodeficiency Virus Disease Course Is Predicted by the Extent of Virus Replication during Primary Infection

Staprans, Silvija I., Dailey, Peter J., Rosenthal, Ann, Horton, Chris, Grant, Robert M., Lerche, Nicholas, ...

To elucidate the relationship between early viral infection events and immunodeficiency virus disease progression, quantitative-competitive and branched-DNA methods of simian immunodeficiency virus...

Route of Simian Immunodeficiency Virus Inoculation Determines the Complexity but Not the Identity of Viral Variant Populations That Infect Rhesus Macaques

Greenier, Jennifer L., Miller, Christopher J., Lu, Ding, Dailey, Peter J., Lü, Fabien X., Kunstman, Kevin J., ...

A better understanding of the host and viral factors associated with human immunodeficiency virus (HIV) transmission is essential to developing effective strategies to curb the global HIV epidemic....

The Liver Is a Major Organ for Clearing Simian Immunodeficiency Virus in Rhesus Monkeys

Zhang, Linqi, Dailey, Peter J., Gettie, Agegnehu, Blanchard, Jim, Ho, David D.

Infection with human or simian immunodeficiency virus (SIV) is characterized by the rapid turnover of both viral particles and productively infected cells. It has recently been reported that the...

Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus–infected monkeys

Fox, Howard S., Weed, Michael R., Huitron-Resendiz, Salvador, Baig, Jamal, Horn, Thomas F.W., Dailey, Peter J., ...

Simian immunodeficiency virus (SIV) infection of rhesus monkeys provides an excellent model of the central nervous system (CNS) consequences of HIV infection. To discern the relationship between...

Quantitative Image Analysis of HIV-1 Infection in Lymphoid Tissue

Ashley T. Haase, Keith Henry, Mary Zupancic, Gerlad Sedgewick, Russell A. Faust, Holly Melroe, ...

A quantitative technique was developed to determine HIV-1 viral burden in two important cellular compartments in lymphoid tissues (LT). Image analysis and in situ hybridization were combined to show...