Peter E. Huber

Intensity-modulated radiotherapy of nasopharyngeal carcinoma: a comparative treatment planning study of photons and protons (2008)

Taheri-Kadkhoda, Zahra, Björk-Eriksson, Thomas, Nill, Simeon, Wilkens, Jan J, Oelfke, Uwe, Johansson, Karl-Axel, ...

Abstract Background The aim of this treatment planning study was to investigate the potential advantages of intensity-modulated (IM) proton therapy (IMPT) compared with IM photon therapy (IMRT) in...

Intensity Modulated Radiotherapy (IMRT) and Fractionated Stereotactic Radiotherapy (FSRT) for children with head-and-neck-rhabdomyosarcoma (2007)

Combs, Stephanie E, Behnisch, Wolfgang, Kulozik, Andreas E, Huber, Peter E, Debus, Jürgen, Schulz-Ertner, Daniela

Abstract Background The present study evaluates the outcome of 19 children with rhabdomyosarcoma of the head-and-neck region treated with Intensity Modulated Radiotherapy (IMRT) or Fractionated...

Tyrosine kinase inhibitor SU6668 represses chondrosarcoma growth via antiangiogenesis in vivo (2007)

Klenke, Frank M, Abdollahi, Amir, Bertl, Elisabeth, Gebhard, Martha-Maria, Ewerbeck, Volker, Huber, Peter E, ...

Abstract Background As chondrosarcomas are resistant to chemotherapy and ionizing radiation, therapeutic options are limited. Radical surgery often cannot be performed. Therefore, additional...

Intensity modulated radiotherapy (IMRT) in patients with carcinomas of the paranasal sinuses: clinical benefit for complex shaped target volumes (2006)

Combs, Stephanie E, Konkel, Stephan, Schulz-Ertner, Daniela, Münter, Marc W, Debus, Jürgen, Huber, Peter E, ...

Abstract Introduction The aim of the study was to evaluate the clinical outcome of intensity modulated radiotherapy (IMRT) in 46 patients with paranasal sinus tumors with special respect to...

Small molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells (2006)

Li, Minglun, Ping, Gong, Plathow, Christian, Trinh, Thuy, Lipson, Kenneth E, Hauser, Kai, ...

Abstract Background Several small receptor tyrosine kinase inhibitors (RTKI) have entered clinical cancer trials alone and in combination with radiotherapy or chemotherapy. The inhibitory spectrum of...

The selective Cox-2 inhibitor Celecoxib suppresses angiogenesis and growth of secondary bone tumors: An intravital microscopy study in mice (2006)

Klenke, Frank, Gebhard, Martha-Maria, Ewerbeck, Volker, Abdollahi, Amir, Huber, Peter E, Sckell, Axel

Abstract Background The inhibition of angiogenesis is a promising strategy for the treatment of malignant primary and secondary tumors in addition to established therapies such as surgery,...

Tumor Cytotoxicity In Vivo and Radical Formation In Vitro Depend on the Shock Wave-Induced Cavitation Dose (2001)

Peter E. Huber, Juergen Debus

Huber, P. E. and Debus, J. Tumor Cytotoxicity In Vivo and Radical Formation In Vitro Depend on the Shock Wave-Induced Cavitation Dose. Radiat. Res. 156, 301–309 (2001). Local tumor therapy using...

Transcriptional network governing the angiogenic switch in human pancreatic cancer

Abdollahi, Amir, Schwager, Christian, Kleeff, Jörg, Esposito, Irene, Domhan, Sophie, Peschke, Peter, ...

A shift of the angiogenic balance to the proangiogenic state, termed the “angiogenic switch,” is a hallmark of cancer progression. Here we devise a strategy for identifying genetic participants...

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis

Abdollahi, Amir, Li, Minglun, Ping, Gong, Plathow, Christian, Domhan, Sophie, Kiessling, Fabian, ...

Pulmonary fibrosis is the consequence of a variety of diseases with no satisfying treatment option. Therapy-induced fibrosis also limits the efficacy of chemotherapy and radiotherapy in numerous...