Per Eystein Lønning

Adjuvant treatment: the contribution of expression microarrays (2007)

Lønning, Per Eystein, Chrisanthar, Ranjan, Staalesen, Vidar, Knappskog, Stian, Lillehaug, Johan

Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters (2006)

Baumbusch, Lars O., Myhre, Simen, Langerød, Anita, Bergamaschi, Anna, Geisler, Stephanie B., Lønning, Per Eystein, ...

Background: The tumor suppressor gene p53 (TP53) controls numerous signaling pathways and is frequently mutated in human cancers. Novel p53 isoforms suggest alternative splicing as a regulatory...

Multilocus analysis of SNP and metabolic data within a given pathway (2006)

Kristensen, Vessela N., Tsalenko, Anya, Geisler, Jurgen, Faldaas, Anne, Grenaker, Grethe Irene, Lingjærde, Ole Christian, ...

Background: Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges...

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Sørlie, Therese, Perou, Charles M., Tibshirani, Robert, Aas, Turid, Geisler, Stephanie, Johnsen, Hilde, ...

The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A...

Aromatase inhibitors and inactivators in breast cancer : These potent inhibitors of oestrogen synthesis may be superior to tamoxifen

Lønning, Per Eystein

Multilocus analysis of SNP and metabolic data within a given pathway

Kristensen, Vessela N, Tsalenko, Anya, Geisler, Jurgen, Faldaas, Anne, Grenaker, Grethe Irene, Lingjærde, Ole Christian, ...

Evaluation of MetriGenix custom 4D™ arrays applied for detection of breast cancer subtypes

Muggerud, Aslaug Aamodt, Johnsen, Hilde, Barnes, Debra A, Steel, Adam, Lønning, Per Eystein, Naume, Bjørn, ...

Genetic variation in putative regulatory loci controlling gene expression in breast cancer

Kristensen, Vessela N., Edvardsen, Hege, Tsalenko, Anya, Nordgard, Silje H., Sørlie, Therese, Sharan, Roded, ...

Candidate single-nucleotide polymorphisms (SNPs) were analyzed for associations to an unselected whole genome pool of tumor mRNA transcripts in 50 unrelated patients with breast cancer. SNPs were...

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Sørlie, Therese, Perou, Charles M., Tibshirani, Robert, Aas, Turid, Geisler, Stephanie, Johnsen, Hilde, ...

The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A...

Aromatase inhibitors and inactivators in breast cancer : These potent inhibitors of oestrogen synthesis may be superior to tamoxifen

Lønning, Per Eystein

Multilocus analysis of SNP and metabolic data within a given pathway

Kristensen, Vessela N, Tsalenko, Anya, Geisler, Jurgen, Faldaas, Anne, Grenaker, Grethe Irene, Lingjærde, Ole Christian, ...

Evaluation of MetriGenix custom 4D™ arrays applied for detection of breast cancer subtypes

Muggerud, Aslaug Aamodt, Johnsen, Hilde, Barnes, Debra A, Steel, Adam, Lønning, Per Eystein, Naume, Bjørn, ...

Genetic variation in putative regulatory loci controlling gene expression in breast cancer

Kristensen, Vessela N., Edvardsen, Hege, Tsalenko, Anya, Nordgard, Silje H., Sørlie, Therese, Sharan, Roded, ...

Candidate single-nucleotide polymorphisms (SNPs) were analyzed for associations to an unselected whole genome pool of tumor mRNA transcripts in 50 unrelated patients with breast cancer. SNPs were...

Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres

Grudic, Amra, Jul-Larsen, Åsne, Haring, Stuart J., Wold, Marc S., Lønning, Per Eystein, Bjerkvig, Rolf, ...

The activation of a telomere maintenance mechanism is required for cancer development in humans. While most tumors achieve this by expressing the enzyme telomerase, a fraction (5–15%) employs a...

Adjuvant treatment: the contribution of expression microarrays

Lønning, Per Eystein, Chrisanthar, Ranjan, Staalesen, Vidar, Knappskog, Stian, Lillehaug, Johan

CHEK2 Mutations Affecting Kinase Activity Together With Mutations in TP53 Indicate a Functional Pathway Associated with Resistance to Epirubicin in Primary Breast Cancer

Chrisanthar, Ranjan, Knappskog, Stian, Løkkevik, Erik, Anker, Gun, Østenstad, Bjørn, Lundgren, Steinar, ...