Kidd, Brian A, Ho, Peggy P, Sharpe, Orr, Zhao, Xiaoyan, Tomooka, Beren H, Kanter, Jennifer L, ...
Abstract Introduction Anti-citrullinated protein antibodies have a diagnostic role in rheumatoid arthritis (RA); however, little is known about their origins and contribution to pathogenesis....
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis (2008)
Zhao, Xiaoyan, Okeke, Nwora, Sharpe, Orr, Batliwalla, Franak M, Lee, Annette T, Ho, Peggy P, ...
Abstract Introduction There is increasing evidence that autoantibodies and immune complexes (ICs) contribute to synovitis in rheumatoid arthritis (RA), yet the autoantigens incorporated in ICs in RA...
Collins, Francis S., Boehnke, Michael, Chandrasekharappa, Settara C., Shearon, Tempie H., Ho, Peggy P., Couch, Fergus J., ...
The human homolog of the Saccharomyces cerevisiae cell division control 27 gene (CDC27) was mapped to human chromosome 17q12-q21 using a panel of human/rodent somatic cell hybrids and localized...
A Radiation Hybrid Map of the BRCA1 Region of Chromosome 17q12-q21 (1993)
Abel, Kenneth J., Boehnke, Michael, Prahalad, Murali, Ho, Peggy P., Flejter, Wendy L., Watkins, Melanie, ...
The chromosomal region 17q12-q21 contains a gene (BRCA1) conferring susceptibility to early-onset familial breast and ovarian cancer. An 8000-rad radiation-reduced hybrid (RH) panel was constructed...
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
Paniagua, Ricardo T., Sharpe, Orr, Ho, Peggy P., Chan, Steven M., Chang, Anna, Higgins, John P., ...
Tyrosine kinases play a central role in the activation of signal transduction pathways and cellular responses that mediate the pathogenesis of rheumatoid arthritis. Imatinib mesylate (imatinib) is a...
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
Paniagua, Ricardo T., Sharpe, Orr, Ho, Peggy P., Chan, Steven M., Chang, Anna, Higgins, John P., ...
Tyrosine kinases play a central role in the activation of signal transduction pathways and cellular responses that mediate the pathogenesis of rheumatoid arthritis. Imatinib mesylate (imatinib) is a...
Heme oxygenase–1 and carbon monoxide suppress autoimmune neuroinflammation
Chora, Ângelo A., Fontoura, Paulo, Cunha, Andreia, Pais, Teresa F., Cardoso, Sílvia, Ho, Peggy P., ...
Heme oxygenase–1 (HO-1, encoded by HMOX1) dampens inflammatory reactions via the catabolism of heme into CO, Fe, and biliverdin. We report that expression of HO-1 dictates the pathologic outcome of...
Luo, Jian, Ho, Peggy P., Buckwalter, Marion S., Hsu, Tiffany, Lee, Lowen Y., Zhang, Hui, ...
Autoimmune encephalomyelitis, a mouse model for multiple sclerosis, is characterized by the activation of immune cells, demyelination of axons in the CNS, and paralysis. We found that TGF-β1...