Paweł Jałoszyński

8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, ‘action-at-a-distance’ mutagenesis and inhibition of replication

Jałoszyński, Paweł, Masutani, Chikahide, Hanaoka, Fumio, Perez, Ana Blanco, Nishimura, Susumu

Mutations in particular codons of c-Ha-ras have a strong activating potential, and an activated ras oncogene has been found in a number of human cancers. Using fragments of the human c-Ha-ras gene...

8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, ‘action-at-a-distance’ mutagenesis and inhibition of replication

Jałoszyński, Paweł, Masutani, Chikahide, Hanaoka, Fumio, Perez, Ana Blanco, Nishimura, Susumu

Mutations in particular codons of c-Ha-ras have a strong activating potential, and an activated ras oncogene has been found in a number of human cancers. Using fragments of the human c-Ha-ras gene...