Paul Trayhurn

The case for strategic international alliances to harness nutritional genomics for public and personal health (2005)

Kaput, Jim, Ordovas, José, Ferguson, Lynnette, Van Ommen, Ben, Rodríguez, Raymond, Allen, Lindsay, ...

Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into...

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

Hoggard, Nigel, Hunter, Leif, Duncan, Jacqueline S., Williams, Lynda M., Trayhurn, Paul, Mercer, Julian G.

Leptin is a 167-aa protein that is secreted from adipose tissue and is important in the regulation of energy balance. It also functions in hematopoiesis and reproduction. To assess whether leptin is...

Zinc-α2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia

Bing, Chen, Bao, Yi, Jenkins, John, Sanders, Paul, Manieri, Monia, Cinti, Saverio, ...

Zinc-α2-glycoprotein (ZAG), a 43-kDa protein, is overexpressed in certain human malignant tumors and acts as a lipid-mobilizing factor to stimulate lipolysis in adipocytes leading to cachexia in...

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

Hoggard, Nigel, Hunter, Leif, Duncan, Jacqueline S., Williams, Lynda M., Trayhurn, Paul, Mercer, Julian G.

Leptin is a 167-aa protein that is secreted from adipose tissue and is important in the regulation of energy balance. It also functions in hematopoiesis and reproduction. To assess whether leptin is...

Zinc-α2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia

Bing, Chen, Bao, Yi, Jenkins, John, Sanders, Paul, Manieri, Monia, Cinti, Saverio, ...

Zinc-α2-glycoprotein (ZAG), a 43-kDa protein, is overexpressed in certain human malignant tumors and acts as a lipid-mobilizing factor to stimulate lipolysis in adipocytes leading to cachexia in...

Appetite and energy balance signals from adipocytes

Trayhurn, Paul, Bing, Chen

Interest in the biology of white adipose tissue has risen markedly with the recent surge in obesity and its associated disorders. The tissue is no longer viewed simply as a vehicle for lipid storage;...

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes

Wang, Bohan, Wood, I. Stuart, Trayhurn, Paul

The effect of hypoxia, induced by incubation under low (1%) oxygen tension or by exposure to CoCl2, on the expression and secretion of inflammation-related adipokines was examined in human...