Paul R. Hazelton

The Reovirus Mutant tsA279 L2 Gene Is Associated with Generation of a Spikeless Core Particle: Implications for Capsid Assembly

Hazelton, Paul R., Coombs, Kevin M.

Previous studies which used intertypic reassortants of the wild-type reovirus serotype 1 Lang and the temperature-sensitive (ts) serotype 3 mutant clone tsA279 identified two ts lesions; one lesion,...

Reovirus ςNS Protein Is Required for Nucleation of Viral Assembly Complexes and Formation of Viral Inclusions

Becker, Michelle M., Goral, Mehmet I., Hazelton, Paul R., Baer, Geoffrey S., Rodgers, Steven E., Brown, Earl G., ...

Progeny virions of mammalian reoviruses are assembled in the cytoplasm of infected cells at discrete sites termed viral inclusions. Studies of temperature-sensitive (ts) mutant viruses indicate that...

Avian Reovirus Temperature-Sensitive Mutant tsA12 Has a Lesion in Major Core Protein σA and Is Defective in Assembly

Xu, Wanhong, Patrick, Megan K., Hazelton, Paul R., Coombs, Kevin M.

Members of our laboratory previously generated and described a set of avian reovirus (ARV) temperature-sensitive (ts) mutants and assigned 11 of them to 7 of the 10 expected recombination groups,...

Role of Ebola Virus Secreted Glycoproteins and Virus-Like Particles in Activation of Human Macrophages

Wahl-Jensen, Victoria, Kurz, Sabine K., Hazelton, Paul R., Schnittler, Hans-Joachim, Ströher, Ute, Burton, Dennis R., ...

Ebola virus, a member of the family Filoviridae, causes one of the most severe forms of viral hemorrhagic fever. In the terminal stages of disease, symptoms progress to hypotension, coagulation...

The Reovirus Mutant tsA279 L2 Gene Is Associated with Generation of a Spikeless Core Particle: Implications for Capsid Assembly

Hazelton, Paul R., Coombs, Kevin M.

Previous studies which used intertypic reassortants of the wild-type reovirus serotype 1 Lang and the temperature-sensitive (ts) serotype 3 mutant clone tsA279 identified two ts lesions; one lesion,...

Reovirus ςNS Protein Is Required for Nucleation of Viral Assembly Complexes and Formation of Viral Inclusions

Becker, Michelle M., Goral, Mehmet I., Hazelton, Paul R., Baer, Geoffrey S., Rodgers, Steven E., Brown, Earl G., ...

Progeny virions of mammalian reoviruses are assembled in the cytoplasm of infected cells at discrete sites termed viral inclusions. Studies of temperature-sensitive (ts) mutant viruses indicate that...

Avian Reovirus Temperature-Sensitive Mutant tsA12 Has a Lesion in Major Core Protein σA and Is Defective in Assembly

Xu, Wanhong, Patrick, Megan K., Hazelton, Paul R., Coombs, Kevin M.

Members of our laboratory previously generated and described a set of avian reovirus (ARV) temperature-sensitive (ts) mutants and assigned 11 of them to 7 of the 10 expected recombination groups,...

Role of Ebola Virus Secreted Glycoproteins and Virus-Like Particles in Activation of Human Macrophages

Wahl-Jensen, Victoria, Kurz, Sabine K., Hazelton, Paul R., Schnittler, Hans-Joachim, Ströher, Ute, Burton, Dennis R., ...

Ebola virus, a member of the family Filoviridae, causes one of the most severe forms of viral hemorrhagic fever. In the terminal stages of disease, symptoms progress to hypotension, coagulation...